Hemoglobin A1c predicts healing rate in diabetes?

Hemoglobin A1c predicts healing rate in diabetic wounds

Before this study from colleagues from Hopkins and Penn, really very few manuscripts have shown a strong correlation.

Adjusted β-coefficients and 95% confidence intervals for the relationship between change in wound area per day and other variables.
Variable* Change in Wound Area Per Day (β) (cm2/day) P-Value
Age (per 12 years) 0.017 (−0.065, 0.100) 0.680
Female (versus male) 0.038 (−0.132, 0.209) 0.659
African American race (versus white race) −0.063 (−0.174, 0.048) 0.263
Body mass index (per 9.76 kg/m2), 0.053 (−0.032, 0.139) 0.220
Wound number (per 1.54 wounds) −0.001 (−0.059, 0.058) 0.982
Total cholesterol (per 44.7 mg/dl) −0.060 (−0.137, 0.017) 0.126
LDL cholesterol (per 41.5 mg/dl) 0.035 (−0.025, 0.094) 0.250
HDL cholesterol (per 15.9 mg/dl) −0.020 (−0.069, 0.029) 0.414
Triglycerides (per 75.4 mmol/l) −0.016 (−0.085, 0.052) 0.641
Systolic blood pressure (per 23.3 mmHg) 0.020 (−0.063, 0.102) 0.641
Diastolic blood pressure (per 13.5 mmHg) −0.074 (−0.151, 0.003) 0.060
Pulse (per 14.3 bpm) 0.025 (−0.037, 0.087) 0.432
Temperature (per 0.58 ° Fahrenheit) 0.015 (−0.048, 0.078) 0.639
White blood cell count (per 2490.42 cells/microliter) 0.118 (−0.085, 0.266) 0.119
Former smoker (versus never smoker) −0.015 (−0.224, 0.067) 0.862
Current smoker (versus never smoker) 0.054 (−0.103, 0.212) 0.496
Neuropathy (versus no neuropathy) −0.079 (−0.224, 0.067) 0.287
Peripheral artery disease (versus no peripheral artery disease) −0.053 (−0.144, 0.038)
HbA1c (per 1.0% point) −0.028 (−0.054, −0.003) 0.027

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.