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Current Management of Peripheral Artery Disease: Focus on Pharmacotherapy @ALPSlimb @USC_Vascular @JCU @ResearchatUSC #ActAgainstAmputation

This from our combined USC and James Cook University team. Bottom line: There are lots of opportunities to make an impact to optimize best medical therapy. Jonathan Golledge, Malindu E. Fernando & David G. Armstrong Peripheral artery disease (PAD) is the occlusion or narrowing of the arteries supplying the lower extremities. Peripheral artery disease has been estimated to... Continue Reading →

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@USC Podiatric Surgeon David G. Armstrong First to Reach 60,000 Citations of Peer Reviewed Publications @KECKSchool_USC @USC_Vascular @alpslimb @ResearchAtUSC @APMA

David G. Armstrong, Professor of Surgery and Director of the Southwestern Academic Limb Salvage Alliance (SALSA) became the first podiatric surgeon in the history of the specialty to reach 60,000 citations of more than 600 peer reviewed publications.   He and his colleagues have become the first podiatric surgeons to publish in a multitude of... Continue Reading →

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Study: Nutritional Interventions May Improve Outcomes of Patients Operated on for Diabetic Foot Infections

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Nutritional Interventions May Improve Outcomes of Patients Operated on for Diabetic Foot Infections: A Single-Center Case-Control Study Nutritional Interventions May Improve Outcomes of Patients Operated on for Diabetic Foot Infections: A Single-Center Case-Control Study Great work from our long-time friend and colleague Prof. Ilker Uckay of Zurich's Balgrist hospital. JDR_9546144 1..6 Nutritional Interventions May Improve... Continue Reading →

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Chronic Wounds @DiseasePrimers @Nature

A magnum opus from Vince Falanga, Rosyln Isseroff, Athena Soulika, Marco Romanelli, Dave Margolis, Suzanne Kapp, Mark Granick, and Keith Harding. Chronic wounds Abstract | Chronic wounds are characterized by their inability to heal within an expected time frame and have emerged as an increasingly important clinical problem over the past several decades, owing to... Continue Reading →

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Barriers to care-seeking for diabetic foot ulceration across multiple levels of the healthcare system @USC_Vascular @USC @ALPSlimb @TzeWoeiTan @JFootAnkleRes

This from our SALSA team let by Tze Woei Tan Introduction The mechanisms for the observed disparities in diabetes-related amputation are poorly understood and could be related to access for diabetic foot ulceration (DFU) care. This qualitative study aimed to understand patients’ personal experiences navigating the healthcare system and the barriers they faced. Methods Fifteen... Continue Reading →

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SC CTSI grant jump-starts first-ever countywide limb preservation program for people with diabetes @SoCalCTSI @USC_Vascular @USC @ResearchatUSC @WeAreLAHealth @RanchoRehab

This from John Tibbetts If untreated, chronic foot wounds threaten the limbs and lives of diabetic patients. High blood sugar associated with diabetes can lead to complications in sensation and circulation limit blood circulation needed to fight off foot infections, leading to diabetic foot ulcers. Many wounds become infected, leading to amputation. More than half... Continue Reading →

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Diabetic Foot Risk Classification at the Time of Type 2 Diabetes Diagnosis and Subsequent Risk of Mortality: 75% Increased Risk for Declining Screening #ActAgainstAmputation @alpslimb

Important work from Wang and coworkers. This from a large population based cohort in the UK. Bottom line: screening matters and identifying those that decline foot exam can be life-extending Diabetic Foot Risk Classification at the Time of Type 2 Diabetes Diagnosis and Subsequent Risk of Mortality: A Population-Based Cohort Study Aim: We aimed to... Continue Reading →

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Exosome-cargoed microRNAs: potential therapeutic molecules for diabetic wound healing

Imagine an exosome cargo delivery system for mRNAs... Diabetic foot ulcers are one of the most common complications of diabetes, requiring repeated surgical intervention and leading to amputation. Owing to the lack of effective drugs, novel therapeutics need to be explored. Decreased angiogenic factors, endothelial cell dysfunction and vascular lumen stenosis impair angiogenesis in diabetic... Continue Reading →

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