Cutting the Cord: Oral Cefadroxil Holds Its Own for Gram-Positive Bacteremia—and Osteomyelitis

Graphical abstract comparing continued intravenous therapy, cefadroxil, and alternative oral therapy for gram-positive bacteremia with or without nonvertebral osteomyelitis, showing similar 90-day survival without clinical failure.

For generations, bacteremia—especially Staphylococcus aureus bacteremia—has almost reflexively meant prolonged IV therapy. But the evidence base continues to chip away at the idea that the route of administration is itself the treatment. A terrific new multicenter study in Open Forum Infectious Diseases, including our world-class infectious-disease colleagues at LA General Medical Center and the Los... Continue Reading →

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Saving Limbs by Design: Opening APMA National in Nashville

Patrick A. DeHeer, Lawrence E. Burns, David G. Armstrong, Shanika L. Hill, and Joseph L. Mills following the APMA 2026 opening session in Nashville.

Nashville, Tennessee — August 6, 2026 There are few better ways to start a national meeting than looking out at a packed room of mission driven folks at 7:30 in the morning. I had the privilege of chairing and lecturing in the opening session of the 2026 American Podiatric Medical Association Annual Scientific Meeting—The National,... Continue Reading →

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The Clean Margin in Diabetic Foot Osteomyelitis: Conceptual Appeal, Practical Uncertainty

Original infographic showing one resected bone margin through three overlapping lenses labeled Surgery, Pathology, and Microbiology, emphasizing that each perspective may define the margin differently.

Margin-directed antibiotic therapy after surgery for diabetic foot osteomyelitis is appealing, but surgical assessment, histopathology, and microbiology often provide different answers. A new Clinical Infectious Diseases Viewpoint explains why multidisciplinary interpretation and prospective standardization are essential.

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Charcot Is a Five-Year Survival Signal #CharcotFoot #ActAgainstAmputation

Charcot neuro-osteoarthropathy outcomes in 140 adults with diabetes: 67% emergency admission by one year, 31% lower-extremity amputation by five years, 33% all-cause mortality by five years, and 44% amputation-free survival by five years.

A new Diabetes Care registry study shows that Charcot neuro-osteoarthropathy is far more than a local foot disorder. Following diagnosis, nearly nine in ten patients required emergency hospitalization, almost one-third underwent amputation, and only 44% were alive and amputation-free at five years.

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When AI Grows Hands: From the Factory Floor to the Hospital Hallway—and Finally, Home

An assistive humanoid robot progresses from a structured factory through a hospital corridor into a warm home, representing the rising trust required of embodied AI.

Large language models can describe the world. Embodied AI must act in it. The likely progression—from factories, to hospitals, to homes—is a rising test of repeatability, accountability, and trust.

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The Wound Pulls the Trigger: Force-Responsive Biomaterials Put Cells in Charge of Repair

Scientific cutaway of a healing skin wound showing repair cells gripping force-responsive molecular tethers in a collagen-like scaffold. As the cells pull, the tethers unfold and release localized golden growth-factor signals at the cell-material interface.

In a new Nature Materials study, traction-force-activated payloads capture the body's own growth factors and release them when repairing cells pull on the scaffold. The work spans living bone and skin models and ex vivo human skin - a striking preclinical step, not yet a treatment for diabetic foot ulcers.

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If the Shoe Fits, Will They Wear It? DIASSIST Shows Adherence Is a Design Problem—not a Patient Problem #ActAgainstAmputation

DIASSIST graphical abstract: a personalized multimodal intervention combining pressure-optimized custom footwear, indoor footwear, education, and motivational interviewing improved prescribed-footwear adherence at 6 and 12 months.

One of the persistent paradoxes in diabetic foot prevention is simple: Diabetes Care, Volume 49, Issue 8. The world’s best protective shoe does no good while sitting beside the door. Now, an important multicenter randomized controlled trial from our longtime Dutch friends and colleagues—led by Lisa Vossen with Jaap van Netten, Sicco Bus, and their... Continue Reading →

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The Foot Selfie Grows Up: From Smartphone Photos to Smart Scales #ActAgainstAmputation

Timeline of home plantar imaging: 2010 home photography, 2017 FootSnap, pre-COVID AI foundations, DFU Challenge 2020, pandemic acceleration, Peru co-creation, BlueDrop in 2025, and the 2026 Empo feasibility study.

A new formative study of an in-home full-color imaging scale offers a glimpse of the Foot Selfie’s next chapter—from early home plantar photography and smartphones to AI, co-creation, and ambient monitoring.

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Every Wound Needs a Passport: The Core Descriptor Set for Diabetes-Related Foot Ulcer Studies #ActAgainstAmputation

An open research passport for diabetes-related foot-ulcer studies, surrounded by the nine domains of the 28-item core descriptor set. The visual shows that common baseline data enable fairer study comparisons and stronger evidence.

A new 28-item core descriptor set gives diabetes-related foot-ulcer studies a common baseline language—so treatments can be compared more fairly and evidence can travel farther.

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Three Generations, Six Pages: APMA News Features USC’s Prof. David G. Armstrong and Daughter Dr. Alexandria Armstrong, #ActAgainstAmputation #DiabeticFoot

APMA News May/June 2026 feature spreads collage

Originally published in APMA News, May/June 2026, pages 16–23. The May/June 2026 issue of APMA News devotes eight pages to a two-part feature: a profile of David G. Armstrong, DPM, MD, PhD, Distinguished Professor of Surgery and Neurological Surgery at the Keck School of Medicine of USC, followed by a companion interview with Alexandria Armstrong,... Continue Reading →

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