Health Services Forms New Limb-Preservation Workgroup @WeAreLAHealth @HarborUCLA_VS @RanchoRehab @LACUSCMedCenter @KeckSchool_USC @USC #ActAgainstAmputation @ALPSLimb

 This article from the LA County Department of Health Services via Evan Raff Diabetes-related amputations represent a major preventable health risk for patients living with diabetes and lower extremity limb loss in particular is one of the most devastating events in a patient’s life, with five-year mortality approaching 70% and even higher in the population... Continue Reading →

The influence of debridement on diabetic foot ulcers: nationwide utilization and outcomes

Tettelbach and coworkers have more compelling data supporting debridement. Objective: To determine the role of debridement when patients are using placental-derived allografts (PDAs), data from two prospective, multicentre, randomised controlled trials (RCTs) were evaluated for the quality or adequacy of debridement on diabetic foot ulcers (DFUs) treated with PDAs. Results were compared with real-world findings via... Continue Reading →

Home temperature monitoring reduces risk of diabetic foot ulcer recurrence by more than half: Meta Analysis #ActAgainstAmputation #DiabeticFoot @ALPSlimb

Superb effort as usual from Golledge and coworkers in evaulating people in diabetic foot remission. Aims: To perform an updated systematic review of randomised controlled trials examining the efficacy of at-home foot temperature monitoring in reducing the risk of a diabetes-related foot ulcer (DFU). Methods: Systematic review performed according to Preferred Reporting Items for Systematic reviews and... Continue Reading →

Flexor Tendon Tenotomy Treatment of the Diabetic Foot: A Multicenter Randomized Controlled Trial #ActAgainstAmputation @ALPSlimb @DiabetesCareADA

Important work from Andersen and coworkers on a potentially reproducible, minimally invasive clinical procedure to reduce pressure on distal digits with flexible deformities. Objective: The aim of this study was to evaluate the effects of needle flexor tendon tenotomy treatment of the diabetic hammertoe deformity. Research design and methods: A multicenter randomized controlled trial of individuals with... Continue Reading →

Meta-Analysis: Outcomes of Surgical and Medical Management of Diabetic Foot Osteomyelitis @UTSW_Plastics @UTSWOrtho

Subtle and compelling work from our toemigos Larry Lavery and Dane Wukich's team led by David Truong. Background. The aim of this study was to evaluate clinical outcomes in the published literature on medical and surgical management of diabetic foot osteomyelitis (DFO). Methods. A PubMed and Google Scholar search of articles relating to DFO was... Continue Reading →

Steps per Day and All-Cause Mortality in Middle-aged Adults in the Coronary Artery Risk Development in Young Adults Study

Insightful work from Paluch and coworkers. Bottom line: just keep walking! Key Points Question  Are step volume or intensity associated with premature mortality among middle-aged Black and White women and men? Findings  In this cohort study of 2110 adults with a mean follow-up of 10.8 years, participants taking at least 7000 steps/d, compared with those taking fewer... Continue Reading →

Investigation of a UK biobank cohort reveals causal associations of self-reported walking pace with telomere length @CommsBio

Walking pace appears to be a vital sign. Superb work from Dempsey and coworkersInvestigation of a UK biobank cohort reveals causal associations of self-reported walking pace with telomere length | Communications Biology Walking pace is a simple and functional form of movement and a strong predictor of health status, but the nature of its association... Continue Reading →

Molecular Pathophysiology of Chronic Wounds: Current State and Future Directions #Theragnostics #Diagnostics @CSHL @UnivMiami

A great perspective from Pastar and coworkers from our long-time friend Marjana Tomic-Canic's lab at University of Miami published in Cold Spring Harbor Perspectives in Biology. Molecular Pathophysiology of Chronic Wounds: Current State and Future Directions Venous leg ulcers, diabetic foot ulcers, and pressure ulcers are complex chronic wounds with multifactorial etiologies that are associated... Continue Reading →

Flap monitoring with incisional negative pressure wound therapy (#NPWT) in diabetic foot patients #ActAgainstAmputation

Clever work from Park and Park in Scientific Reports Flap monitoring with incisional negative pressure wound therapy (NPWT) in diabetic foot patients Various types of flaps are considered as reconstructive options for patients with diabetic foot ulcer. However, flap reconstruction for diabetic foot ulcer treatment is particularly challenging becauseof the relatively limited collateral perfusion in... Continue Reading →

Inforatio technique in wound healing- punching your way to success?

Fascinating work from our Danish colleagues. They are testing their (and our collective) observation regarding the disconnect between why punch biopsies seem to heal quite rapidly but chronic wounds don't. Introduction Diabetic foot ulcers (DFUs) are associated with extensive consequences for the affected patients and treatment of these hard-to-heal ulcers is known for being challenging.... Continue Reading →

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