David G. Armstrong, DPM, MD, PhD, of the Keck School of Medicine of USC, has concluded a 13-day, five-city academic tour of China โ delivering keynotes at the SIDC meeting in Shijiazhuang, the 14th CODHy China Congress in Shanghai, and the 6th Yat-sen Endocrine and Metabolism Forum in Guangzhou, and being conferred an Honorary Visiting Professorship at Peking University First Hospital.
Notes from #Guangzhou: The Yat-sen (้ธไป) Forum, Macrophage Modulation, and the City Where the Doctor Became a Revolutionary @alpslimb #ActAgainstAmputation
The final stop of our China tour: the SUNYIXIAN (้ธไป) Forum in Guangzhou, hosted alongside Prof. Li Yan's group at Sun Yat-sen Memorial Hospital. A talk on the global evidence for macrophage modulation in diabetic foot ulcers โ delivered, fittingly, in the city where Sun Yat-sen trained as a physician before he ever led a revolution. Medicine and revolution, born in the same place.
When to Apply (and When to Wait): Bacterial Fluorescence as a Theragnostic Gate for Skin Substitutes in DFUs and VLUs #ActAgainstAmputation #Diagnostics #Theragnostics #MolecuLight #CAMPs @AlishaOropallo @USC_Vascular @KeckSchool_USC @ALPSlimb
A lovely piece by our friend and colleague Alisha Oropallo and her team at Northwell, just out in the International Wound Journal. The question they ask is one we should be asking more loudly: before you reach for a CAMP (cellular/acellular/matrix-like product, i.e., a "skin substitute") on a chronic DFU or VLU, what is the... Continue Reading →
More Podiatrists, Fewer Amputations: A New JAMA Network Open Study Maps Geographic Variation in Medicare Diabetic Foot Wounds #ActAgainstAmputation @alpslimb
A new paper from Ioana Popescu and colleagues โ including Aksone Nouvong and Vincent Rowe at UCLA Geffen, with the RAND Corporation team โ just landed in JAMA Network Open. It is, to my eye, the strongest population-level evidence yet that access to podiatry is access to limb preservation. The setup: 707,971 Medicare fee-for-service beneficiaries... Continue Reading →
Notes from #Shijiazhuang: Delivering the Keynote on the Team Approach to #LimbPreservation #ActAgainstAmputation @alpslimb
Notes from Shijiazhuang: two SIDC talks with China Resources Double-Crane on the Team Approach to Limb Preservation and a hands-on WIfI classification consultation with Prof. Lianrui Guo. The classification works. The team works. The language is portable.
Notes from #Shanghai: The First-Ever #LimbPreservation Session at #CODHy China โ Standing Between Generations with Profs. Boulton and Prof. Wuquan Deng
CODHy China in Shanghai: the first-ever Diabetic Foot and Limb Preservation session in the 14-year history of the meeting. Co-chairing alongside my mentor Prof. Andrew Boulton on one side and my mentee Prof. Wuquan Deng of Chongqing on the other. The lineage works. The language is portable. The team approach travels.
Peking University First Hospital Confers Visiting Professorship on USC’s David G. Armstrong
Ceremony at Beijing's historic teaching hospital marks new chapter in transpacific collaboration on diabetic foot disease and limb preservation.
Malvern at 40, and 30 Years On: One Last Bow for Profs. Boulton and Rayman, and a Long Road Ahead #Malvern40 #ActAgainstAmputation #DFCon #LimbPreservation @ALPSLimb
Forty years of the Malvern Diabetic Foot Meeting. Thirty years of mine. One last bow from Andrew Boulton in the chair. A look back at the long arc โ from a Benedictine priory in 1085 to Joslin in 1928 to DFCon in 2000 to ALPS in 2020 โ and a look forward to DFCon 26, DFUpdate, traveling fellowships, and the next generation already climbing the hill.
From Scar to Salamander? Adult Mice Regrow Amputated Digits After Sequential FGF2 โ BMP2 #regeneration #amputation @NatureComms
Yu and colleagues from Ken Muneoka's group show that sequential FGF2 then BMP2 treatment flips an adult mouse digit amputation from fibrosis to regeneration โ rebuilding the distal phalanx with a growth plate, plus a parallel response that regenerates a synovial joint complex with tendon, ligament, and a sesamoid-like bone. The regeneration-competent cells are already in our wound beds. We just have to learn what to say to them.
“No DFU Goes Unstudied”: The Diabetic Foot Consortium #DFC Biomarker Platform Study from Brings Master-Protocol Design to Wound Healing #DFU #DiabeticFoot
Our colleagues at the NIDDK Diabetic Foot Consortium have published the methodologic scaffolding the field has needed: a platform studyโmaster-protocol trial design borrowed from oncology and COVID-19 vaccinesโapplied for the first time to DFU biomarker validation. Their mantra: No DFU Goes Unstudied.