SALSA/Rancho Los Amigos Guidelines for Return To Activity in Remission #ToeFlowandGo @USC @RanchoResearchI @USC_Vascular

Here are the instructions we give our patients upon returning to prescriptive shoes / activity following healing of a diabetic foot ulcer, foot reconstruction or partial foot amputation in remission. Dosing Activity and Returning to Pre-Ulcer function in Diabetic Foot Remission: Guidelines from SALSA and Rancho Los Amigos Introduction Shoe Wear Schedule: Day 1 Day […]

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Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds

Intriguing work from Verbanic and coworkers from UCSB and UCLA. Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds Chronic wounds represent a large and growing disease burden. Infection and biofilm formation are two of the leading impediments of wound healing, suggesting an important role for the microbiome of […]

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Spread on skin- Complete wound closure following a single topical application of a novel autologous homologous skin construct: first evaluation in diabetic foot ulcers

This early experience from our pan-university team from Keck of USC, Brigham and Women’s/HMS, Northwestern and Drexel.

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Increase of stiffness in plantar fat tissue in diabetic patients

This from Gwak and coworkers in the Journal of Biomechanics. Plantar soft tissue stiffening in diabetes leads to a risk of developing ulcers. There are relatively few studies providing methods for quantifying the mechanical properties of skin and fat in the plantar tissue of diabetic patients. Previous studies used linear or non-linear single layer deformable […]

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Limb Salvage: The Heart and Soul (Sole?) of Vascular Surgery

Compelling stuff from Behrendt and Debus in European Journal of Vascular and Endovascular Surgery It can sometimes be challenging to understand the self concept of vascular surgery in a time where the aorta dominates both conferences and journals. While pioneers in interventional vascular surgery use highly innovative techniques to climb mount vascular, the vast majority […]

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Glycemic control and diabetic foot ulcer outcomes: A systematic review and meta-analysis of observational studies

Superb work from our Hopkins colleagues Lane and coworkers Highlights Role of glycemic control in diabetic foot ulcers (DFUs) is unclear. Previous meta-analyses have included small numbers of studies. Higher A1C and fasting glucose are associated with increased amputation risk in patients with DFUs. A1C and glucose were not associated with wound healing. Abstract Objective […]

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Making the equivocal unequivocal: standardization of clean margins in diabetic foot osteomyelitis

This from Brian Schmidt and Christine Jarocki of University of Michigan Background The prevalence of diabetes mellitus continues to rise. Diabetic foot ulcers with osteomyelitis are a diabetes-related complication presenting a significant burden to this cohort. A cure to diabetic foot osteomyelitis remains elusive and standard of care has failed to improve outcomes. To advance […]

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“Nature’s Microsurgeons” Star in Innovative Telemedicine Procedure @USC @KeckMedUSC

This by way of Lex Davis of KSOM’s public affairs department! David G. Armstrong, DPM, MD, PhD , co-director of Keck Medicine of USC’s limb salvage program, had a patient with a problem. Post-surgery, the patient had developed necrotic tissue at the site of the wound—according to an AI algorithm, the wound was 46% necrotic. […]

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Where did “10,000 steps a day” come from? What do the data say, anyway?

A really thoughtful piece from Tanner Garrity in Inside Hook asks “Where does 10,000 steps really come from? Enjoy Welcome to The Workout From Home Diaries. Throughout our national self-isolation period, we’ll be sharing single-exercise deep dives, offbeat belly-busters and general get-off-the-couch inspiration that doesn’t require a visit to your (now-shuttered) local gym. Once a day, […]

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