Reduced Mortality: Why GLP-1s and the “Dream Team” of Podiatry, Diabetes Care, and Opthalmology Are Changing the DFU Game @DiabetesCareADA #ActAgainstAmputation #Survival

We’ve known for a long time that a diabetic foot ulcer (DFU) isn’t just a wound on the bottom of a foot—it’s a massive red flare for a patient’s overall health. But a recent nationwide study in Diabetes Care just put some sobering, and ultimately hopeful, numbers behind that reality. The data from this massive... Continue Reading →

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Measuring what we Manage: Why the Mother of Modern Nursing is the Grandmother of Big-Time Data Viz

You'll often hear us saying "you can't manage what you can't measure", but for those of us in the trenches of limb salvage and wound healing, this isn't just a mantra—it is a moral imperative. And if we want to see the future of how we treat the "patient-in-place," we need to look back nearly... Continue Reading →

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The “Iron Curtain” of the Foot: More Insights into Arterial Obstruction in CLTI #ActAgainstAmputation #PAD #DiabeticFoot

When we talk about Chronic Limb-Threatening Ischemia (CLTI), we often focus on what we can see on an angiogram. But what is actually happening inside those vessels at a microscopic level? A comprehensive histopathological analysis of amputated limbs is shedding new light on the specific patterns of arterial obstruction that lead to limb loss. This... Continue Reading →

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Marrying Data with Common Sense: Is it Safe to Amputate a Toe at Bedside in an Inpatient Unit? #ActAgainstAmputation

In the world of diabetic foot care, we often find ourselves at a crossroads when a patient presents with isolated toe necrosis. Traditionally, this meant an automatic ticket to the operating room (OR) for a conventional amputation surgery (CAS). But as operating rooms become increasingly crowded and resources stretched thin, we have to ask: is... Continue Reading →

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Disruptive Tech in the Clinic: AI-Powered Thermography for Early DFU Detection #ActAgainstAmputation

A new diagnostic accuracy study demonstrates how the combination of smartphone-based thermography and artificial intelligence (AI) could revolutionize routine screening for diabetic foot ulcers (DFUs). This technology offers a scalable, objective alternative to traditional manual exams, which are often episodic and highly dependent on examiner expertise. The Tech: TFScan The study evaluated TFScan, a system... Continue Reading →

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Imaging Infected Bone: WBC SPECT/CT vs. MRI in Diabetic Foot Osteomyelitis #ActAgainstAmputation

Our colleagues Larry Lavery and Andrew Crisologo, alongside lead author Orhan Öz, have published a significant prospective study in Diabetologia. Their work tackles one of the most difficult challenges in limb preservation: accurately diagnosing diabetic foot osteomyelitis (DFO) and, crucially, knowing when the infection is actually gone. The Challenge of the "Gold Standard" While bone... Continue Reading →

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A 3D Panoramic View Into the Body: Introducing RUS-PAT Imaging #ActAgainstAmputation @Caltech @USC_Vascular @NeurosurgeryUSC @KeckSchool_USC @USC @NatBME

Our colleagues at Caltech and USC Vascular Surgery and Neurosurgery, including Lihong Wang, Charles Liu, Tze Woei Tan, and Jonathan Russin, have unveiled a major leap in medical imaging. Published in Nature Biomedical Engineering, the team introduces Hybrid Rotational Ultrasound and Photoacoustic Tomography (RUS-PAT). Think of it as a high-speed, 3D panoramic camera for our... Continue Reading →

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An Enigma Wrapped in Edema: Rethinking Charcot Arthropathy #ActAgainstAmputation #DiabeticFoot

Please see our manuscript here. Winston Churchill famously described Russia as ‘a riddle,wrapped in a mystery, inside an enigma’ in a 1939 broadcast .Indeed, two centuries after the birth of Jean-­ Martin Charcot, thecondition that bears his name remains, as Churchill might say,an enigma wrapped in oedema—an inflammatory mystery toooften misread or misdiagnosed as mundane.... Continue Reading →

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Phage Therapy: A Precision Strike Against Diabetic Foot Osteomyelitis #ActAgainstAmputation

Exciting new data from our friend and colleague Ben Lipsky and his team highlights a potential shift in how we approach one of our most stubborn challenges: Staphylococcus aureus (StA) in diabetic foot osteomyelitis (DFO). Current standards of care for DFO are often unsatisfactory. This Phase 2, randomized, double-blind, placebo-controlled trial investigated BX211, a personalized... Continue Reading →

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Another Frontier in Limb Preservation: Automated Periosteal Distraction? #ActAgainstAmputation #WoundHealing

In the journey to eliminate preventable amputations, we continue to look for ways to harness the body’s own regenerative potential. Our latest brief communication describes a significant “first” in the field: the application of fully automated tibial periosteal distraction (PD) for limb preservation. While it has long been understood that applying controlled “tension-stress” to tissue... Continue Reading →

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