Forty years of the Malvern Diabetic Foot Meeting. Thirty years of mine. One last bow from Andrew Boulton in the chair. A look back at the long arc โ from a Benedictine priory in 1085 to Joslin in 1928 to DFCon in 2000 to ALPS in 2020 โ and a look forward to DFCon 26, DFUpdate, traveling fellowships, and the next generation already climbing the hill.
From Scar to Salamander? Adult Mice Regrow Amputated Digits After Sequential FGF2 โ BMP2 #regeneration #amputation @NatureComms
Yu and colleagues from Ken Muneoka's group show that sequential FGF2 then BMP2 treatment flips an adult mouse digit amputation from fibrosis to regeneration โ rebuilding the distal phalanx with a growth plate, plus a parallel response that regenerates a synovial joint complex with tendon, ligament, and a sesamoid-like bone. The regeneration-competent cells are already in our wound beds. We just have to learn what to say to them.
“No DFU Goes Unstudied”: The Diabetic Foot Consortium #DFC Biomarker Platform Study from Brings Master-Protocol Design to Wound Healing #DFU #DiabeticFoot
Our colleagues at the NIDDK Diabetic Foot Consortium have published the methodologic scaffolding the field has needed: a platform studyโmaster-protocol trial design borrowed from oncology and COVID-19 vaccinesโapplied for the first time to DFU biomarker validation. Their mantra: No DFU Goes Unstudied.
Hold the Antibiotics Before Bone BiopsyโOr Not? A Provocative New Meta-Analysis from #Lavery, #Wukich, #Peters and Team #DFO #Osteomyelitis #DiabeticFoot
A new systematic review and meta-analysis from Lavery, Wukich, Peters and team asks whether pre-biopsy antibiotics actually reduce bacterial culture yield in suspected diabetic foot osteomyelitis. Spoiler: maybe not.
The Doctor Is In (the Wound Clinic): Dan Powell, MD on Embedding Behavioral Health in Limb Preservation #MalvernDFC2026 #DiabeticFoot @alpslimb
At today's Malvern Diabetic Foot Conference, Georgetown psychiatrist Dan Powell, MD made the case for embedding behavioral health into wound healing and limb preservation programs โ with Hopkins data showing a 3-day median reduction in length of stay when psychiatric consultation is proactive rather than reactive.
98.4%: What Fran Game’s National Diabetic Foot Audit Lecture Should Change About How We Talk About the Diabetic Foot and DFUs #DiabeticFoot #Malvern2026 #ToeFlowGo #NDFA #LimbPreservation @alpslimb
Field notes from Malvern, year 40. With thanks to @FranGame for the slide that should hang in every multidisciplinary clinic in the world. I came in this morning expecting another graceful walk through the National Diabetes Foot Care Audit dashboard. What I got instead was the most useful reframe I have heard in a long... Continue Reading →
Who’s in Charge of the OR? Granados et al. Reimagine the Surgical Team in the Age of #AI and #Robotics
A new Frontiers in Science Lead Article from Granados, Khanna, Fischer, and colleagues at King's College London โ with Prokar Dasgupta as senior author โ takes a swing at one of the harder questions in modern surgery. When the operating room becomes a sensorized, situationally aware ecosystem with embodied AI agents, robotic scrub assistants, and... Continue Reading →
Mรถnckeberg: How a Quiet 1903 Autopsy Became the Loudest Plain Film in Limb Preservation #DiabeticFoot #PAD #CLTI #LimbPreservation #ActAgainstAmputation #PMAC #Calcification
Johann Georg Mรถnckeberg was a Hamburg patrician, born in 1877. His father โ same name โ was a senator of the free city, with the Mรถnckebergstrasse running from the Rathaus to the Hauptbahnhof named after him. The son grew up in a household where the name was already on the streets. He studied medicine at... Continue Reading →
If It Doesn’t Look Like a Tree: #Fractals, #Microcirculation, and Why Small Artery Disease Is So Easy to See
A long-time friend's offhand observation in Bremen โ that small artery disease is easy to see on an angiogram because it doesn't look like nature โ leads to Mandelbrot, Murray's law, and a quantifiable complexity index for the diabetic foot.
On the Whole Etymology of the Hole in Skin: Wound, Ulcer & a Dinner in Bremen with Sicco Bus #DiabeticFoot #Etymology #LimbPreservation
Over dinner at EWMA-DEWU in Bremen with longtime collaborator and renowned biomechanist Prof. Sicco Bus, talk drifted from classification to language โ and to why English insists on two words for the same hole in the body. A slow look at what wound vs. ulcer is silently encoding every time we write it down.