@USC Podiatric Surgeon Armstrong Named Inaugural @UTHealthSA Lawrence B. Harkless Leadership Awardee #ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC @APMA

David G. Armstrong, Professor of Surgery and Director of the Southwestern Academic Limb Salvage Alliance (SALSA) at Keck School of Medicine of University of Southern California (USC) became the inaugural recipient of the University of Texas Health Science Center of San Antonio's Lawrence B. Harkless Leadership Award.The award, created in honor of long-time podiatric surgeon... Continue Reading →

Pedal arterial calcification score is associated with hemodynamic change and major amputation after infrainguinal revascularization for chronic limb-threatening ischemia #ActAgainstAmputation @ALPSlimb @UCSFVascular

pMAC / Pedal Medial Arterial Calcification Score Yet more important work from our Toe- and Flowmigos @ UCSF. Objective: Pedal medial arterial calcification (pMAC) is associated with major amputation in patients with chronic limb-threatening ischemia (CLTI). We hypothesize that this association would be related to unresolved distal ischemia. We investigated relationships across pMAC score, hemodynamic change,... Continue Reading →

Biomarkers of Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) in the Diabetic Foot: A Medical Record Review

Make the link between chronic kidney disease, pedal calcification...and even Charcot? This from our SALSAmigos at Washington University, St. Louis. Aims: Determine the prevalence and relative risk of having single and combinations of biomarkers of chronic kidney disease-mineral bone disorder (CKD-MBD) syndrome in the diabetic foot from an electronic medical record (EMR) review. Methods: Review of 152... Continue Reading →

Microenvironment-Based Diabetic Foot Ulcer Nanomedicine #ActAgainstAmputation @ALPSlimb

An ambitious review from Huang and coworkers Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial infection. Given its pathogenesis, the DFU microenvironment is rather complicated and characterized by hyperglycemia, ischemia, hypoxia, hyperinflammation, and persistent infection. However, the current... Continue Reading →

Outcomes of short versus long duration of antibiotic therapy for residual osteomyelitis in surgically resected diabetic foot infection #ActAgainstAmputation @ALPSlimb

More data (this report from Motaganahalli and coworkers to support the likely contention that, in general, shorter may be better - or at very least not worse. Introduction: Optimal treatment duration for residual osteomyelitis (OM) post-amputation in diabetic foot infection (DFI) remains unclear, with resultant heterogeneity in prescribing noted in clinical practice. We aimed to identify... Continue Reading →

Smart Wearable Systems for the Remote Monitoring of Selected Vascular Disorders of the Lower Extremity: A Systematic Review #C2SHiP #Wearable #Diagnostic #Theragnostic

A good contribution from Souza and coworkers This systematic review aims at providing an overview of the state of the art regarding smart wearable systems (SWS) applications to monitor the status of patients suffering from vascular disorders of the lower extremity. Peer-reviewed literature has been analyzed to identify employed data collection methods, system characteristics, and... Continue Reading →

Relationship between WIfI Stage and Quality of Life at the time of Revascularization in the @BEST_CLI Trial #ActAgainstAmputation @ALPSlimb

Another important contribution to the literature from the Best CLI trial from Jeff Syracuse and coworkers. Type of Research: This is prospectively collected data from a randomized clinical trial. Key Findings: Patients presenting with WIfI stage 4 were more often current smokers, had end stage renal disease, diabetes, and were not independently ambulatory. WIfI stage 4, compared... Continue Reading →

Surgery without postoperative antibiotic treatment in diabetic foot #osteomyelitis is not associated with recurrence or limb loss #ActAgainstAmputation @ALPSlimb

Compelling findings from our long-time SALSAmigo, the pride of Gran Canaria, Javier Aragon-Sanchez and coworkers Surgery without postoperative antibiotic treatment in diabetic foot osteomyelitis is not associated with recurrence or limb loss Not using antibiotics after surgical treatment of diabetic foot osteomyelitis was not associated with failure of the surgery, recurrences, or limb loss. Antibiotics... Continue Reading →

Diabetic foot disease in subjects with End-stage renal Disease: A nationwide study over 14 years highlighting an emerging threat ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC

This from our colleagues YY Huang and coworkers along with our unit. Diabetic foot disease in subjects with End-stage renal Disease: A nationwide study over 14 years highlighting an emerging threat Cheng-Wei Lin David G. Armstrong Chung-Huei Huang Shih-Yuan Hung Pi-Hua Liu 1 Yu-Yao Huang 1 Show all authors Show footnotes Open AccessPublished:October 28, 2022DOI:https://doi.org/10.1016/j.diabres.2022.110134 Highlights •This nationwide... Continue Reading →

Gut Dysbiosis and Diabetic Foot Ulcer: Role of Probiotics @ALPSLimb #Nutrition

As we continue to explore the complex interaction between us and our microbial/bacterial overlords, here is another addition to the literature Gut Dysbiosis and Diabetic Foot Ulcer: Role of Probiotics Citation: Awasthi, A.; Corrie, L.; Vishwas, S.; Gulati, M.; Kumar, B.; Chellappan, D.K.; Gupta, G.; Eri, R.D.; Dua, K.; Singh, S.K. Gut Dysbiosis and Diabetic... Continue Reading →

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