“Spooky Action at a Distance”: The Most Comprehensive Review Yet of Physiologic Neuromodulation for Limb Preservation #ActAgainstAmputation #Neuromodulation #SpinalCordStimulation #CLTI @BurnsTrauma @KeckSchool_USC @ResearchatUSC @USC

Our new paper in Burns and Trauma presents the most comprehensive review yet of spooky action at a distance therapies for diabetic limb preservation — from spinal cord stimulation and splenic ultrasound to remote ischemic conditioning and tibial transport. Five modalities, three mechanistic pathways, one shared destination: tissue repair at a distance.

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Dosing Walking Like a Drug: An AI Chatbot for Diabetic Foot Remission Following Limb Reconstruction #ActAgainstAmputation #DiabeticFoot #Remission #AI #Chatbot @SensorsMDPI @KeckSchool_USC @ALPSLimb @USC_Vascular

A new protocol paper in Sensors describes a chatbot that doses walking like a drug for patients in diabetic foot remission.

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You Are What You Eat — And That’s Pretty Inflammatory: A New Composite Biomarker for DFU Risk #ActAgainstAmputation #DFU #Nutrition @ALPSLimb

A novel inflammation-nutrition biomarker — the neutrophil percentage-to-albumin ratio (NPAR) — shows strong association with diabetic foot ulcer risk in a 1,002-patient study from Xi'an, China, reinforcing that what patients eat and how they inflame are inseparable in the diabetic foot.

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Your Phone Already Knows What You Can’t Feel: There’s an app for that…A Smartphone App for Detecting Diabetic Neuropathy #ActAgainstAmputation #DPN #DigitalHealth #Neuropathy @JDSTonline @Stanford @ALPSLimb

A Stanford team demonstrates that a smartphone app measuring vibration perception thresholds can detect large-fiber sensory deficits in patients with diabetes — a potential advance for accessible, patient-operated neuropathy screening.

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Sunday Morning Wish Fulfilled: AI Meets Thermometry in Diabetic Foot Remission — A Scoping Review of 60 Studies #ActAgainstAmputation #AI #Thermography #DFU

A scoping review from Kanazawa University maps 60 studies on AI-powered thermography for diabetic foot detection — and reveals a critical gap: nearly half of all studies were tested only in controlled environments, not the real world where feet actually live.

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The Pressure Is Worth It: Custom Footwear Guided by In-Shoe Pressure Data Is Cost-Effective for Preventing DFU Recurrence #ActAgainstAmputation #DFU #Remission @DiabetologyMdpi @ALPSLimb

A cost-effectiveness analysis of the DIAFOS trial shows that in-shoe plantar pressure-guided custom footwear saves over €8,000 per ulcer prevented — and adherent patients push the probability of cost-effectiveness to 94%. The economic case for prevention just got stronger.

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From Foot to Fatality: The #DiabeticFootAttack Is Real, and It’s Worse Than You Think @alpslimb #ActAgainstAmputation

A new single-center study from the Netherlands quantifies the devastating outcomes of the diabetic foot attack: only 48.5% wound closure, 46% major amputation by 12 months, 26% one-year mortality, and 12-month amputation-free survival of just 39.7%. Time is tissue.

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25 Years of Plantar Pressure Research in #DiabeticFoot Ulcers: A Bibliometric Deep Dive @MDABORATORY #ActAgainstAmputation

A new bibliometric analysis from Wei and colleagues at Capital Medical University in Beijing maps 25 years (2000–2024) of global research on plantar pressure and diabetic foot ulcers — over 2,100 publications indexed in the Web of Science Core Collection. The findings tell a story that will feel familiar to many of us who have... Continue Reading →

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Are We Flying Blind? Largest Study Yet Shows Some Bedside Tests for PAD in Diabetes Are Barely Better Than a Coin Flip #DiabeticFoot #PAD #LimbPreservation #VascularMedicine @NormahaniP @AlunDavies @ImperialCollege #ActAgainstAmputation #Diagnostics

This is the kind of study that should make every clinician who manages the diabetic foot sit up a little straighter. The DM PAD study — a prospective, multicentre diagnostic accuracy study across 16 NHS centres and 604 patients — just landed in Health Technology Assessment. Led by Burgess, Normahani, and colleagues at Imperial College... Continue Reading →

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Limb Preservation: The Global State of Play in 2026 — Keynote at ADFA’s Inaugural Meeting in Paris #ActAgainstAmputation @ALPSLimb #DiabeticFoot #LimbPreservation #Paris

Honored to deliver the keynote at the inaugural meeting of ADFA in Paris.

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