On diabetic foot, wound healing, amputation prevention, and the merger of consumer tech with medical devices
Vitamin D has been medicine for millennia — we just didn't know it. A tour through its history, its biology, and what the evidence now says about its role in diabetic foot ulcer healing.
A new study from our USC group shows Medicaid patients with diabetic foot ulcers face 18% higher odds of infection hospitalization and 72% higher odds of major amputation — despite being younger and having comparable comorbidity burden after matching. The data point to structural vulnerability, not biology.
Our new paper is out today in Diabetology, and I'm really proud of this one. It's a narrative review—co-authored with Bijan Najafi and Shervanthi Homer-Vanniasinkam—that traces the entire arc of offloading from the 1930s to right now. We called it "From Plaster to Pixels" because that's genuinely what's happened. From plaster-of-Paris casts in leprosy clinics... Continue Reading →
A landmark Singapore study of 2,798 patients shows podiatric care associated with 69% lower mortality and 26% better amputation-free survival in diabetic foot ulcers. Podiatrists don't just save limbs — they save lives.
Three decades of putting weird ideas together with weird people — now you can see and share the whole thing. 👉 Explore the DGA Research Constellation For more than three decades, I've had the pleasure of doing something that doesn't have a clear name. It doesn't fit neatly on a CV. There's no NIH study... Continue Reading →
We talk a lot about the big-ticket items in diabetic peripheral neuropathy (DPN)—glucose control, hemoglobin A1c, advanced glycation end products. But what about the stuff sitting quietly in your multivitamin? A new review from Ntoga and colleagues out of the Diabetic Foot Clinic at Democritus University of Thrace—working with collaborators at Aristotle University of Thessaloniki—makes... Continue Reading →
Natalie Armstrong presents on the Food-Energy-Water nexus and the public health impacts of data center development at the NSF C2SHiP weekly ThinkTank. A framework for decision makers, hyperscalers, industry, and communities to get to yes — or no — faster.
There's a moment in most engineering disciplines when you have to confront an uncomfortable truth: the "best" solution on paper isn't always the best solution in the field. NASA learned this with the Space Shuttle — a magnificent machine that required 25,000 people and six months to turn around between flights. The Saturn V, by... Continue Reading →
Nearly a Million Words Later: What 17 Years of DiabeticFootOnline Look Like in a Word Cloud I recently did something I probably should have done a long time ago. I pointed an AI at every single blog post on this site—all 3,835 of them—and asked it to show me what nearly two decades of writing... Continue Reading →
For years, we’ve looked at chronic wounds through a relatively narrow lens—clean them, debride them, and hope the host's biology eventually kicks into gear. But as our understanding of the wound microbiome deepens, it’s becoming clear that these microbial communities aren't just "there"—they are active architects of the healing (or non-healing) environment. A recent review... Continue Reading →
