Tag: amputation prevention

Malvern at 40, and 30 Years On: One Last Bow for Profs. Boulton and Rayman, and a Long Road Ahead #Malvern40 #ActAgainstAmputation #DFCon #LimbPreservation @ALPSLimb

Forty years of the Malvern Diabetic Foot Meeting. Thirty years of mine. One last bow from Andrew Boulton in the chair. A look back at the long arc — from a Benedictine priory in 1085 to Joslin in 1928 to DFCon in 2000 to ALPS in 2020 — and a look forward to DFCon 26, DFUpdate, traveling fellowships, and the next generation already climbing the hill.

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From Scar to Salamander? Adult Mice Regrow Amputated Digits After Sequential FGF2 → BMP2 #regeneration #amputation @NatureComms

Yu and colleagues from Ken Muneoka's group show that sequential FGF2 then BMP2 treatment flips an adult mouse digit amputation from fibrosis to regeneration — rebuilding the distal phalanx with a growth plate, plus a parallel response that regenerates a synovial joint complex with tendon, ligament, and a sesamoid-like bone. The regeneration-competent cells are already in our wound beds. We just have to learn what to say to them.

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Mönckeberg: How a Quiet 1903 Autopsy Became the Loudest Plain Film in Limb Preservation #DiabeticFoot #PAD #CLTI #LimbPreservation #ActAgainstAmputation #PMAC #Calcification

Johann Georg Mönckeberg was a Hamburg patrician, born in 1877. His father — same name — was a senator of the free city, with the Mönckebergstrasse running from the Rathaus to the Hauptbahnhof named after him. The son grew up in a household where the name was already on the streets. He studied medicine at... Continue Reading →

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Ninety-Five Thousand Hands on the Work: A #Citation Milestone, and Why This is Always a Team Sport #ActAgainstAmputation #LimbPreservation @ALPSLimb @KeckSchool_USC @USC_Vascular

Google Scholar ticked over to 95,006 citations overnight. The number is real — the story behind it isn't mine. An h-index of 134 and an i10-index of 568 reflect 568 conversations between collaborators, residents, fellows, patients, and friends. A note on what citations actually are, why limb preservation is and always will be a team sport, and gratitude to everyone whose hand has been on the work.

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When it comes to #DiabeticFoot infections, Moderate ≠ Severe: New #Biomarker Data Reignite and Support the Case for Splitting Categories #IDSA #WIfI #ActAgainstAmputation

An email from Ben Lipsky brings new biomarker data — IL-17, IL-12p70, HMGB1, IL-8, CRP — that may be the strongest case yet for splitting "moderate" and "severe" diabetic foot infections in the IDSA and WIfI classification.

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The Lennon and McCartney of the Diabetic Foot, Remastered: Rescuing a Hilarious 2008 @ABoultonMD Toast for #Malvern40 #ActAgainstAmputation #DFCon #LimbPreservation @ALPSLimb

Eighteen years ago, Larry Lavery and I stood up at the Malvern Diabetic Foot Meeting dinner and performed four Beatles rewrites in honor of Andrew Boulton. It brought the house down. As Malvern turns 40, here are the videos — writers' room, performance, applause, and Abbey walls — rescued, remastered, and archived for the record.

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“Spooky Action at a Distance”: The Most Comprehensive Review Yet of Physiologic Neuromodulation for Limb Preservation #ActAgainstAmputation #Neuromodulation #SpinalCordStimulation #CLTI @BurnsTrauma @KeckSchool_USC @ResearchatUSC @USC

Our new paper in Burns and Trauma presents the most comprehensive review yet of spooky action at a distance therapies for diabetic limb preservation — from spinal cord stimulation and splenic ultrasound to remote ischemic conditioning and tibial transport. Five modalities, three mechanistic pathways, one shared destination: tissue repair at a distance.

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You Are What You Eat — And That’s Pretty Inflammatory: A New Composite Biomarker for DFU Risk #ActAgainstAmputation #DFU #Nutrition @ALPSLimb

A novel inflammation-nutrition biomarker — the neutrophil percentage-to-albumin ratio (NPAR) — shows strong association with diabetic foot ulcer risk in a 1,002-patient study from Xi'an, China, reinforcing that what patients eat and how they inflame are inseparable in the diabetic foot.

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Your Phone Already Knows What You Can’t Feel: There’s an app for that…A Smartphone App for Detecting Diabetic Neuropathy #ActAgainstAmputation #DPN #DigitalHealth #Neuropathy @JDSTonline @Stanford @ALPSLimb

A Stanford team demonstrates that a smartphone app measuring vibration perception thresholds can detect large-fiber sensory deficits in patients with diabetes — a potential advance for accessible, patient-operated neuropathy screening.

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Sunday Morning Wish Fulfilled: AI Meets Thermometry in Diabetic Foot Remission — A Scoping Review of 60 Studies #ActAgainstAmputation #AI #Thermography #DFU

A scoping review from Kanazawa University maps 60 studies on AI-powered thermography for diabetic foot detection — and reveals a critical gap: nearly half of all studies were tested only in controlled environments, not the real world where feet actually live.

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