Absence of Evidence or Evidence of Absence? @SennevilleEric and Ben Lipsky on Bone Biopsy in Diabetic Foot Osteomyelitis #DFO #osteomyelitis #DFU #DFI #ActAgainstAmputation

Senneville and Lipsky return with a measured rejoinder in Clinical Infectious Diseases (April 2026), arguing that the Lagrand trial shows the absence of evidence of superiority โ€” not definitive equivalence โ€” between ulcer-bed and bone biopsy for guiding antibiotic therapy in diabetic foot osteomyelitis.

Empirical Antibiotic Therapy in Diabetic Foot Ulcers: A Double-Edged Sword? #DiabeticFootUlcers #AntibioticTherapy #HospitalizationRates #ActAgainstAmputation @absteward #IDSA

In a landscape where clinicians are increasingly exploring novel approaches to diabetic foot ulcer management, a recent study led by Brian Schmidt from the University of Michiganโ€”co-authored by Rodica Pop-Busui, president of the American Diabetes Association, Keith Kaye, of the Robert Wood Johnson Medical School and Dr. David G. Armstrong, a leading podiatric surgeon and... Continue Reading →

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