On diabetic foot, wound healing, amputation prevention, and the merger of consumer tech with medical devices
In recent years, the therapeutic potential of probiotics has gained considerable attention, particularly in the context of gut health and immune modulation. However, their role in cutaneous immunity and wound healing remains an emerging field of study. A fascinating study published in The FASEB Journal sheds light on the promising effects of postbiotic lactobacilli on... Continue Reading →
Advancements in Chronic Wound Management Chronic wounds, such as diabetic foot ulcers (DFUs), present a significant challenge in medical practice due to their susceptibility to infection and the subsequent risk of amputation. Traditional methods of detecting bacterial loads in wounds rely on costly and time-consuming lab work, which often delays treatment. However, recent advancements in... Continue Reading →
Diabetic foot ulcers (DFUs) remain a serious concern for clinicians, researchers, and patients alike, posing risks that range from infection to amputation. However, new research led by Amy Cambpbell and coworkers from Elizabeth Grice’s lab at the University of Pennsylvania provides fresh insights into the role of bacterial factors, specifically staphyloxanthin in Staphylococcus aureus, in... Continue Reading →
As we continue to explore the complex interaction between us and our microbial/bacterial overlords, here is another addition to the literature Gut Dysbiosis and Diabetic Foot Ulcer: Role of Probiotics Citation: Awasthi, A.; Corrie, L.; Vishwas, S.; Gulati, M.; Kumar, B.; Chellappan, D.K.; Gupta, G.; Eri, R.D.; Dua, K.; Singh, S.K. Gut Dysbiosis and Diabetic... Continue Reading →
This initial look into what may be a routine survey of metagenomic data from week to week. Led by FASMA's Adam Isaac, CosmosID's (National Science Foundation Director Emerita) Prof. Rita Colwell and our team. Objective: Diabetic foot ulcers (DFUs) are characterised by the presence of many microbes, some of which may not be identified by traditional... Continue Reading →
A Clinical Study to Evaluate Autofluorescence Imaging of Diabetic Foot Ulcers Using a Novel Artificial Intelligence Enabled Noninvasive Device Great work from our long-time friend and colleague Vijay Viswanathan and coworkers pushing diagnostics and theragnostics forward. Fluorescence of Bacteria Diabetic foot ulcers, with worldwide prevalence ranging from 12%-25%, are an important cause of nontraumatic lower... Continue Reading →
This excellent work from Le and coworkers strongly suggests that using a point of care diagnostic device (Moleculight) can identify elevated bacterial load and influence medical decision making. Objective: High bacterial load contributes to chronicity of wounds and is diagnosed based on assessment of clinical signs and symptoms (CSS) of infection, but these characteristics are poor... Continue Reading →
Will we soon see more visual diagnostics for wounds? Congratulations to our colleagues in Melbourne for these intriguing data. Diabetic foot infections are a major cause of hospitalization, and delayed treatment can lead to numerous complications. The aim of this research was to investigate high-resolution spectroscopy of the wound center and periwound area for real-time... Continue Reading →
Dakin’s solution, also known as diluted sodium hypochlorite (0.5%), is an antiseptic used to kill germs and prevent bacterial growth in wounds. It was first developed during World War I by Henry Drysdale Dakin and Alexis Carrel. Their collaboration arose from the urgent need to reduce the very high rates of wound infection, morbidity, and... Continue Reading →
