On diabetic foot, wound healing, amputation prevention, and the merger of consumer tech with medical devices
The logic behind antibiotic-loaded bone cement (ALBC) in the infected diabetic foot gets more attractive the longer you stare at it. Pack a debrided, infected wound with PMMA carrying vancomycin or gentamicin and you buy three things at once: a local antibiotic depot eluting at concentrations no IV line could safely deliver, obliteration of dead... Continue Reading →
Intriguing work by Ehya and coworkers. Abstract This study explored the clinical effectiveness of antibiotic-loaded bone cement on primary treatment of diabetic foot infection. This is a randomized controlled study, including thirty-six patients with diabetic foot ulcer complicated by osteomyelitis who had undergone treatment between May 2018 and December 2019. Patients were randomly divided into... Continue Reading →
Crowther and coworkers publish this work in Antimicrobial Agents and Chemotherapy lending further strength to the goal of maximizing antimicrobial therapy at the site of infection. Diabetic foot ulcers are notoriously difficult to heal, with ulcers often becoming chronic, in many cases leading to amputation despite weeks or months of antibiotic therapy in addition to... Continue Reading →
