Application and Clinical Effectiveness of Antibiotic-Loaded Bone Cement in the Treatment of Neuropathic Diabetic Foot Ulcers Complicated by Osteomyelitis: A Randomized Controlled Trial

Intriguing work by Ehya and coworkers. Abstract This study explored the clinical effectiveness of antibiotic-loaded bone cement on primary treatment of diabetic foot infection. This is a randomized controlled study, including thirty-six patients with diabetic foot ulcer complicated by osteomyelitis who had undergone treatment between May 2018 and December 2019. Patients were randomly divided into... Continue Reading →

Efficacy of topical vancomycin and gentamicin loaded calcium sulfate beads or systemic antibiotics in eradicating polymicrobial biofilms isolated from diabetic foot infections

Crowther and coworkers publish this work in Antimicrobial Agents and Chemotherapy lending further strength to the goal of maximizing antimicrobial therapy at the site of infection. Diabetic foot ulcers are notoriously difficult to heal, with ulcers often becoming chronic, in many cases leading to amputation despite weeks or months of antibiotic therapy in addition to... Continue Reading →

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