Relevance of BEST-CLI trial endpoints in a tertiary care limb preservation program

In a recent study conducted by a team from the University of California, San Francisco (UCSF), including Iris H. Liu, MD, Rym El Khoury, MD, Jade S. Hiramoto, MD MAS, Warren J. Gasper, MD, Peter A. Schneider, MD, Shant M. Vartanian, MD, and Michael S. Conte, MD, the relevance of the BEST-CLI trial endpoints was... Continue Reading →

Apples and oranges? A comparison of BEST-CLI to BASIL-2 #JVascSurg #UCSFVascular

Insightful, data-rich commentary as expected from our flowmigos Conte and O'Banion The Battle of the Limb Preservation Trials: BEST-CLI vs. BASIL-2 Two major randomized clinical trials comparing endovascular and open surgical approaches for patients with chronic limb-threatening ischemia (CLTI) - BEST-CLI and BASIL-2 - reported seemingly contradictory results recently. In the larger BEST-CLI trial, patients... Continue Reading →

Relationship between WIfI Stage and Quality of Life at the time of Revascularization in the @BEST_CLI Trial #ActAgainstAmputation @ALPSlimb

Another important contribution to the literature from the Best CLI trial from Jeff Syracuse and coworkers. Type of Research: This is prospectively collected data from a randomized clinical trial. Key Findings: Patients presenting with WIfI stage 4 were more often current smokers, had end stage renal disease, diabetes, and were not independently ambulatory. WIfI stage 4, compared... Continue Reading →

BEST-CLI: The results are in and they’re likely practice-altering ActAgainstAmputation @ALPSlimb @Best_CLI #AHA22

This from our colleagues Alik Farber, Matt Menard and Ken Rosenfeld. Likely to be a game-changer in how patients with CLTI are addressed. The first results from the BEST-CLI randomised controlled trial (RCT) of 1,830 patients show that surgical bypass with adequate single-segment great saphenous vein (GSV) is a more effective revascularisation strategy for patients with chronic limb-threatening ischaemia (CLTI) who are deemed to be suitable... Continue Reading →

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