Tag: calcification

We Moved to the Toe to Escape Calcification — and It Followed Us There: Digital Artery Calcification, Falsely-High Toe Pressures, and a 20–30 mmHg Temporary Fix #DiabeticFoot #PAD #CLTI #ToePressure #Calcification #LimbPreservation #ActAgainstAmputation @alpslimb

We moved to the toe pressure precisely because digital arteries were supposed to be spared from calcification. A new JVS-Vascular Insights study from Welling, Bakker, Ferraresi and colleagues finds digital artery calcification in nearly 30% of limbs, shows it doubles one-year limb-event risk, and that it falsely elevates toe pressure — with a simple fix: when calcium shows on the foot film, subtract 20–30 mmHg.

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Mönckeberg: How a Quiet 1903 Autopsy Became the Loudest Plain Film in Limb Preservation #DiabeticFoot #PAD #CLTI #LimbPreservation #ActAgainstAmputation #PMAC #Calcification

Johann Georg Mönckeberg was a Hamburg patrician, born in 1877. His father — same name — was a senator of the free city, with the Mönckebergstrasse running from the Rathaus to the Hauptbahnhof named after him. The son grew up in a household where the name was already on the streets. He studied medicine at... Continue Reading →

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The “Iron Curtain” of the Foot: More Insights into Arterial Obstruction in CLTI #ActAgainstAmputation #PAD #DiabeticFoot

When we talk about Chronic Limb-Threatening Ischemia (CLTI), we often focus on what we can see on an angiogram. But what is actually happening inside those vessels at a microscopic level? A comprehensive histopathological analysis of amputated limbs is shedding new light on the specific patterns of arterial obstruction that lead to limb loss. This... Continue Reading →

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Calcium makes everything harder :) – Predicting Microsurgical Morbidity with PAD Grading in Limb Preservation #GLASS #MAC #ActAgainstAmputation

Screenshot Screenshot Screenshot Microsurgical limb salvage is one of the most complex, high-stakes interventions in modern reconstructive surgery. For patients with peripheral artery disease (PAD), the decision to proceed with free tissue transfer (FTT) is fraught with uncertainty—especially when calcified, fragile vessels may compromise flap viability from the outset. A new study by Felder and colleagues,... Continue Reading →

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Medial Arterial Calcification Score is Associated with Increased Risk of Major Limb Amputation #DiabeticFoot #ActAgainstAmputation #Diabetes #PAD #CLTI

Congratulations to our combined UNC and USC team led by Kate McGinigle and Alex DiBartolomeo. This provides further data supporting the use of medial arterial calcification (MAC) score as a useful surrogate for risk. Alexander D DiBartolomeo 1, Sydney E Browder 2, Sebouh Bazikian 1, Diwash Thapa 2, Sooyeon Kim 2, Avital Yohann 2, David... Continue Reading →

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Pedal arterial calcification score is associated with hemodynamic change and major amputation after infrainguinal revascularization for chronic limb-threatening ischemia #ActAgainstAmputation @ALPSlimb @UCSFVascular

pMAC / Pedal Medial Arterial Calcification Score Yet more important work from our Toe- and Flowmigos @ UCSF. Objective: Pedal medial arterial calcification (pMAC) is associated with major amputation in patients with chronic limb-threatening ischemia (CLTI). We hypothesize that this association would be related to unresolved distal ischemia. We investigated relationships across pMAC score, hemodynamic change,... Continue Reading →

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Biomarkers of Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) in the Diabetic Foot: A Medical Record Review

Make the link between chronic kidney disease, pedal calcification...and even Charcot? This from our SALSAmigos at Washington University, St. Louis. Aims: Determine the prevalence and relative risk of having single and combinations of biomarkers of chronic kidney disease-mineral bone disorder (CKD-MBD) syndrome in the diabetic foot from an electronic medical record (EMR) review. Methods: Review of 152... Continue Reading →

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Below-the-ankle arterial disease: a new marker of coronary artery disease in patients with diabetes and foot ulcers

Important work from our long-time friends Luigi Uccioli and coworkers. Some, including our friend Elissa Altin of Yale, have suggested that this might lead to us getting radiographs to identify arterial calcification that could help identify PAD, CLTI and even CAD. What do you think? Aim: The aim of the current study is to evaluate the... Continue Reading →

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