On diabetic foot, wound healing, amputation prevention, and the merger of consumer tech with medical devices
Chronic wounds are biological computers stuck in a boot loop. Sharp debridement is Control-Alt-Delete — the histological reboot that converts a chronic wound back into an acute one. Only then can you run the apps.
Biofilms are the silent drivers of chronicity in diabetic foot ulcers (DFUs). We talk about them constantly. We blame them for stalled healing. But when you peel back the layers of current literature, how much hard clinical evidence do we actually have that our interventions are destroying them? In our latest systematic review, published in... Continue Reading →
In the complex world of wound care, innovation often finds inspiration in nature. Nitric oxide (NO), a simple yet potent molecule, is gaining recognition for its remarkable antimicrobial and antibiofilm properties. A recent review by Roberts et al., Harnessing the Power of Our Immune System: The Antimicrobial and Antibiofilm Properties of Nitric Oxide, highlights the growing... Continue Reading →
Diabetic foot ulcers (DFUs) remain a serious concern for clinicians, researchers, and patients alike, posing risks that range from infection to amputation. However, new research led by Amy Cambpbell and coworkers from Elizabeth Grice’s lab at the University of Pennsylvania provides fresh insights into the role of bacterial factors, specifically staphyloxanthin in Staphylococcus aureus, in... Continue Reading →
Important work from our SALSAmigos in Leeds. We see a slow and steady march toward companion diagnostics for our patients. Here we see fluorescence-guided debridement as an example of this. OBJECTIVE To estimate comparative healing rates and decision-making associated with the use of bacterial autofluorescence imaging in the management of diabetic foot ulcers (DFUs). RESEARCH... Continue Reading →
