Tibial Transverse Transport (TTT), Angiogenesis, and Limb Preservation: More support as an adjunct to care? #ActAgainstAmputation #DiabeticFoot #CLTI

A recent study published in ScienceDirect has explored the role of tibial transport in limb preservation and wound healing for patients with diabetes and peripheral artery disease8. Tibial transport is a surgical technique that can improve blood circulation and promote healing in diabetic foot ulcers. In this blog post, we will discuss the findings of this... Continue Reading →

Medial Arterial Calcification Score is Associated with Increased Risk of Major Limb Amputation #DiabeticFoot #ActAgainstAmputation #Diabetes #PAD #CLTI

Congratulations to our combined UNC and USC team led by Kate McGinigle and Alex DiBartolomeo. This provides further data supporting the use of medial arterial calcification (MAC) score as a useful surrogate for risk. Alexander D DiBartolomeo 1, Sydney E Browder 2, Sebouh Bazikian 1, Diwash Thapa 2, Sooyeon Kim 2, Avital Yohann 2, David... Continue Reading →

Combined evaluation of blood flow and tissue perfusion in diabetic feet by intra-arterial dynamic 4DCT imaging #ActAgainstAmputation #DiabeticFoot #Radiology

Fascinating continued work from our Belgian colleagues. Critical limb ischemia is associated with high mortality and major amputations. Intra-arterial digital subtraction angiography (IADSA) has been the reference standard but has some shortcomings including the two-dimensional projection and the lack of tissue perfusion information. The aim of this exploratory study is to examine four-dimensional computed tomography... Continue Reading →

Apples and oranges? A comparison of BEST-CLI to BASIL-2 #JVascSurg #UCSFVascular

Insightful, data-rich commentary as expected from our flowmigos Conte and O'Banion The Battle of the Limb Preservation Trials: BEST-CLI vs. BASIL-2 Two major randomized clinical trials comparing endovascular and open surgical approaches for patients with chronic limb-threatening ischemia (CLTI) - BEST-CLI and BASIL-2 - reported seemingly contradictory results recently. In the larger BEST-CLI trial, patients... Continue Reading →

Intersocietal PAD guidelines on the Diabetic Foot #ActAgainstAmputation #IWGDF

Here is the link to the guidelines for peripheral artery disease in people with diabetes. Diabetes-related foot complications have become a major cause of morbidity and are implicated in most major and minor amputations globally. Approximately 50% of people with diabetes and a foot ulcer have peripheral artery disease (PAD) and the presence of PAD... Continue Reading →

Journal of the American Medical Association: Diabetic Foot Ulcers @JAMA_Current #ActAgainstAmputation #DiabeticFoot

From JAMA Armstrong, Tan, Boulton, and Bus, JAMA. 2023;330(1):62-75. doi:10.1001/jama.2023.10578 In diabetic foot disease, tissue loss,ischemia, and infection frequentlyoverlap. However, one is frequentlymore dominant than the other atdifferent times in the life cycle of anacute-on-chronic event. Here, theamount of tissue loss, ischemia, andfoot infection can be ordinally gradedto help predict outcome and assist incommunicating a plan... Continue Reading →

American Heart Association Advocates for Early Detection and Team-Based Care in Response to Disproportionate Impact of Peripheral Artery Disease in People of Color #ActAgainstAmputation #AmericanHeartAssociation

FOR IMMEDIATE RELEASE AMERICAN HEART ASSOCIATION ADVOCATES FOR EARLY DETECTION AND TEAM-BASED CARE IN RESPONSE TO DISPROPORTIONATE IMPACT OF PERIPHERAL ARTERY DISEASE IN PEOPLE OF COLOR LOS ANGELES, June 18, 2023 — In a new scientific statement published in the renowned Journal 'Circulation', a collective of esteemed medical researchers, including David G. Armstrong, Professor of... Continue Reading →

BASIL-2 points towards endovascular-first revascularisation strategy in CLTI patients @VascularNews

In the BASIL-2 (Bypass versus angioplasty for severe ischaemia of the leg) trial of 345 patients with chronic limb-threatening ischaemia (CLTI), a best endovascular treatment-first revascularisation strategy was associated with better amputation-free survival than a vein bypass-first strategy in those who required an infrapopliteal repair—with or without a more proximal infrainguinal procedure. This result was... Continue Reading →

Cost of Treatment of Neuroischemic Ulcers of the Lower Extremity in Patients with Peripheral Artery Disease in the United States ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC @JAPMAFeetTweets @APMA

This from our team USC and colleagues Paul Saatsoglou and Susan Pitman-Lowenthal. Bottom line: This study analyzed the cost of treating neuroischemic ulcers (a type of wound) on the lower extremities in patients with peripheral artery disease using medical and hospital claims records submitted for reimbursement to private insurance, Medicare, and Medicaid. The study population... Continue Reading →

BEST-CLI: The results are in and they’re likely practice-altering ActAgainstAmputation @ALPSlimb @Best_CLI #AHA22

This from our colleagues Alik Farber, Matt Menard and Ken Rosenfeld. Likely to be a game-changer in how patients with CLTI are addressed. The first results from the BEST-CLI randomised controlled trial (RCT) of 1,830 patients show that surgical bypass with adequate single-segment great saphenous vein (GSV) is a more effective revascularisation strategy for patients with chronic limb-threatening ischaemia (CLTI) who are deemed to be suitable... Continue Reading →

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