On diabetic foot, wound healing, amputation prevention, and the merger of consumer tech with medical devices
An email from Ben Lipsky brings new biomarker data — IL-17, IL-12p70, HMGB1, IL-8, CRP — that may be the strongest case yet for splitting "moderate" and "severe" diabetic foot infections in the IDSA and WIfI classification.
In a recent study by Coye et al. (2023), with many of long-time SALSAmigos as coauthors , the effectiveness of C-reactive protein (CRP)/albumin, erythrocyte sedimentation rate (ESR)/albumin ratio, ESR, CRP, and albumin were evaluated to differentiate bone and soft tissue infection in persons with diabetes[1]. The study retrospectively evaluated 242 individuals admitted to the hospital... Continue Reading →
Great work from our colleagues at IKEM and Manchester. Bottom line: Pay attention to CRP, polymorphisms to methylenetetrahydrofolate reductase (MTHFR) as well as low TCPO2 Key points: The aim of our study was to assess the risk factors for major amputation in patients with CLTI and DFU during a 2-year follow-up after ACT.One hundred and... Continue Reading →
