Chronic wounds are biological computers stuck in a boot loop. Sharp debridement is Control-Alt-Delete โ the histological reboot that converts a chronic wound back into an acute one. Only then can you run the apps.
Current and Future Directions in Fluorescence Imaging Guided Debridement #ActAgainstAmputation #Diagnostics #Theragnostics @ResearchatUSC @USC_vascular @keckschool_usc
Advancements in Chronic Wound Management Chronic wounds, such as diabetic foot ulcers (DFUs), present a significant challenge in medical practice due to their susceptibility to infection and the subsequent risk of amputation. Traditional methods of detecting bacterial loads in wounds rely on costly and time-consuming lab work, which often delays treatment. However, recent advancements in... Continue Reading →
Bone Resection Versus Bone Curettage in Diabetic Foot Osteomyelitis: which is preferred? #ActAgainstAmputation #ALPSlimb
Diabetic foot osteomyelitis (DFO) requires effective management to expedite healing and mitigate complications. A recent study compared bone resection with bone curettage in treating DFO. Conducted from January 2017 to January 2022, the study retrospectively analyzed 31 patients' clinical records post-surgery. Results showcased shorter healing times in the resection group (mean: 5.70 ยฑ 6.05 weeks)... Continue Reading →
Diabetic foot ulcers: weekly versus second weekly debridement: Study #ActAgainstAmputation #WoundHealing
Title: Diabetic Foot Ulcers: Weekly vs. Second-Weekly Conservative Sharp Wound Debridement Introduction:Diabetic foot ulcers (DFU) present a significant challenge in managing patients with diabetes, as they are both common and difficult to heal. Conservative sharp wound debridement (CSWD) is a vital component of DFU care, aimed at removing necrotic tissue and promoting healing. However, determining... Continue Reading →
The influence of debridement on diabetic foot ulcers: nationwide utilization and outcomes
Tettelbach and coworkers have more compelling data supporting debridement. Objective: To determine the role of debridement when patients are using placental-derived allografts (PDAs), data from two prospective, multicentre, randomised controlled trials (RCTs) were evaluated for the quality or adequacy of debridement on diabetic foot ulcers (DFUs) treated with PDAs. Results were compared with real-world findings via... Continue Reading →
Inforatio technique in wound healing- punching your way to success?
Fascinating work from our Danish colleagues. They are testing their (and our collective) observation regarding the disconnect between why punch biopsies seem to heal quite rapidly but chronic wounds don't. Introduction Diabetic foot ulcers (DFUs) are associated with extensive consequences for the affected patients and treatment of these hard-to-heal ulcers is known for being challenging.... Continue Reading →
The Use of Point-of Care Bacterial Autofluorescence Imaging in the Management of Diabetic Foot Ulcers: A Pilot Randomized Controlled Trialย #Diagnostics #Theragnostics
Important work from our SALSAmigos in Leeds. We see a slow and steady march toward companion diagnostics for our patients. Here we see fluorescence-guided debridement as an example of this. OBJECTIVE To estimate comparative healing rates and decision-making associated with the use of bacterial autofluorescence imaging in the management of diabetic foot ulcers (DFUs). RESEARCH... Continue Reading →
Ultrasound-Assisted Wound (UAW) Debridement in the Treatment of Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis @JosLuisLzaroMa1 #Diabeticfoot @alpslimb ๏ฟผ
More and more data to support improvement in wound optimization with ultrasound assisted wound debridement from our long-time friends from the Complutense in Madrid. A systematic review and meta-analysis were carried out to investigate the effect of ultrasound-assisted wound (UAW) debridement in patients with diabetic foot ulcers (DFUs). All selected studies were evaluated using the... Continue Reading →
A microbial-load-guided debridement decision tree using bacterial fluorescence imaging #DiabeticFoot #ActAgainstAmputation
Strong concept from Cole and Coe. One can see the future of theragnostic-driven care in works like this. Use of a bacterial fluorescence imaging system to target wound debridement and accelerate healing: a pilot study Objective: Optimal wound-bed preparation consists of regular debridement to remove devitalised tissues, reduce bacterial load, and to establish an environment... Continue Reading →