Can GLP-1 Receptor Agonists Help Prevent Amputations? A New National Study from USC Suggests Yes @KeckSchool_USC @USC_Vascular @ALPSlimb #ActAgainstAmputation

GLPโ€‘1 Receptor Agonists and Limb Outcomes: What a 645,000โ€‘Patient Study Tells Us A nationwide retrospective cohort analysis published this week in Diabetes Care explores whether glucagonโ€‘like peptideโ€‘1 receptor agonists (GLPโ€‘1 RAs) confer advantages over sodiumโ€“glucose cotransporterโ€‘2 inhibitors (SGLT2i) for lowerโ€‘extremity events in type 2 diabetes. Led by Drโ€ฏTzeโ€‘Woei Tan, the investigation examined 645,121 individuals newly started on either drug class between... Continue Reading →

What’s the prevalence of prediabetes, worldwide? @DiabetesCareADA

Click above for superb data from Rooney and coworkers. OBJECTIVE To estimate the global, regional, and national prevalence of prediabetes, defined by impaired glucose tolerance (IGT) or impaired fasting glucose (IFG). RESEARCH DESIGN AND METHODS We reviewed 7,014 publications for high-quality estimates of IGT (2-h glucose, 7.8โ€“11.0 mmol/L [140โ€“199 mg/dL]) and IFG (fasting glucose, 6.1โ€“6.9... Continue Reading →

Flexor Tendon Tenotomy Treatment of the Diabetic Foot: A Multicenter Randomized Controlled Trial #ActAgainstAmputation @ALPSlimb @DiabetesCareADA

Important work from Andersen and coworkers on a potentially reproducible, minimally invasive clinical procedure to reduce pressure on distal digits with flexible deformities. Objective: The aim of this study was to evaluate the effects of needle flexor tendon tenotomy treatment of the diabetic hammertoe deformity. Research design and methods: A multicenter randomized controlled trial of individuals with... Continue Reading →

The At Risk Foot: Time to Focus on Prevention #DiabeticFoot #ActAgainstAmputation @DiabetesCareADA @USC_Vascular@USC @KeckSchool_USC @APMA @ALPSlimb

The At-Risk Diabetic Foot: Time to Focus on Prevention Just published in the journal Diabetes Care by our combined team including Bob Frykberg, Loretta Vileikyte, Andrew Boulton and me

An Enigma Wrapped in Edema: Charcot Neuropathic OsteoArthropathy @DiabetesCareADA @ALPSlimb #ActAgainstAmputation

Important work from Jeffcoate and Game in Diabetes Care continues the slow, steady march toward measuring, managing, and understanding what I like to call an enigma wrapped in edema. The Charcot Foot Reflects a Response to Injury That Is Critically Distorted by Preexisting Nerve Damage: An Imperfect Storm William Jeffcoate and Fran Game It has... Continue Reading →

Health Care Service and Outcomes Among an Estimated 6.7 Million Ambulatory Care Diabetic Foot Cases in the U.S.ย 

This from our @UofA / @BCM, UTSouthwestern and Oklahoma SALSA team. 6.7 million diabetic foot ulcers, 785 million diabetes-related outpatient visits and 5.5 billion visits overall suggest that diabetic foot ulcers are common, complex, and costly. Compareย this frequently silent and sinister problem to CHF, MI, stroke. OBJECTIVE: To evaluate ambulatory clinical cases of diabetic foot... Continue Reading →

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