A vicious cycle: employment challenges associated with diabetes foot ulcers in an economically marginalized Southwest US sample ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC @TzeWoeiTan @VascularAZ

Great work from Tze Woei Tan and coworkers. Aim: To describe patients’ reported employment challenges associated with diabetic foot ulcers (DFUs). Methods: Fifteen patients from under-resourced communities in Southern Arizona, with a history of DFUs and/or amputations, were recruited from a tertiary referral center from June 2020 to February 2021. Participants consented to an audio-recorded semi-structured phone... Continue Reading →

@USC Prof. David G. Armstrong honored with Distinguished Investigator Award at Association for Clinical and Translational Research ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC

https://youtu.be/P1qv0Qg_EWM The ACTS Distinguished Investigator Award for Translation from Proof of Concept toWidespread Clinical Practice recognizes the senior investigator whose innovative research oreducation leadership has had a major impact on or through clinical and translational science,specifically in the realm of implementation and dissemination of translational solutions to illnessand clinical problems.  For Immediate Release David G.... Continue Reading →

Loss of Insurance Leads to Loss of Limb: An Eye-opening Study in the Annals of Vascular Surgery ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC @AVSgJournal

Loss of Insurance Leads to Loss of Limb: An Eye-opening Study in the Annals of Vascular Surgery April 8, 2023 - A significant study recently published in the Annals of Vascular Surgery has uncovered a troubling correlation between loss of health insurance coverage and increased risk of amputation. Led by Dr. Tze Woei Tan, a... Continue Reading →

Unmet needs in diabetes-related foot ulcer (DFU) treatment

Diabetic foot ulcers (DFUs) are a common and severe complication of diabetes, affecting approximately 34% of people with the disease. Despite advancements in treatment, there are still several unmet needs in the care of diabetic foot ulcers that can lead to poor outcomes, including prolonged healing time, infection, hospitalization, and amputation. Some of the key... Continue Reading →

Outcomes of integrated surgical wound treatment mode based on tibial transverse transport for diabetic foot wound #ActAgainstAmputation @ALPSLimb #DiabeticFoot

Congratulations to Chang and coworkers on this effort. This makes us want to reach back to work from our team a dozen or so years ago, where we failed to really explore this fascinating area of creating, in essence, a distress signal in the bone leading to upregulation of factors that can potentially help toward... Continue Reading →

Senescent Diabetic Foot Disease: Upstream comprehensive management of individuals with diabetes with multimorbidity and frailty to #ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC @VirginiePhD_POD @AeroMD

This manuscript from our combined Quebec/ Palermo / USC family. Virginie Blanchette, David G. Armstrong, Laura Drudi and Manfredi Rizzo This manuscript constitutes a commentary on: “Retrospective cohort study of long-term outcomes and prognostic factors for survival after lower extremity amputation in patients with diabetes” by Vuorlaakso et al. (2023). We aim to contribute to... Continue Reading →

Allogenic Adipose-Derived Stem Cells in Diabetic Foot Ulcer Treatment: Clinical Effectiveness

Intriguing work from our friend and colleague Prof. Beata Rakowska and coworkers from Poland Although encouraging results of adipose-derived stem cell (ADSC) use in wound healing are available, the mechanism of action has been studied mainly in vitro and in animals. This work aimed to examine the safety and efficacy of allogenic ADSCs in human... Continue Reading →

Effects of wear and tear of therapeutic footwear in patients remission. A 5-year follow-up study @ALPSlimb #ActAgainstAmputation #DiabeticFoot

From our colleagues in Madrid anchored by our long-time friend Jose Luis Lazaro Martinez. This was posted previously here. Aims To assesses the relationship between the wear and tear of therapeutic footwear (TF) and the risk of recurrence in diabetes remission patients. Methods Remission patients (N = 115) participated in this 5-year prospective study in a specialized Diabetic Foot Unit between... Continue Reading →

Do Anti-Biofilm Antibiotics Have A Place in the Treatment of Diabetic Foot Osteomyelitis? @ALPSlimb #ActAgainstAmputation

Here is a copy of a preprint from our long-time friend and colleague Eric Senneville and coworkers. The choice of antibiotic regimens to use in patients presenting with diabetic foot osteomyelitis and their duration differs according to the situation. Antibiotics play a more important role in the medical option where no infected bone has been... Continue Reading →

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