Tag: gene therapy

Gene Therapy Emerges as a Potentially New Tool in Wound Healing for People with Vascular Disease: The LEGenD-1 Trial

Published today in Circulation: Cardiovascular Interventions, the LEGenD-1 trial represents a step toward a potential milestone in regenerative medicine and limb preservation. The study, titled “Anatomically Directed Lower Extremity Gene Therapy for Ulcer Healing: A Double-Blind, Randomized, Placebo-Controlled Study,” demonstrates that gene therapy can safely potentially accelerate wound healing in patients with chronic limb-threatening ischemia... Continue Reading →

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Armstrong reports on early results from first-ever gene therapy in wound healing study at vascular biology symposium @USC @ResearchatUSC @USC_vascular

David G. Armstrong, Professor of Surgery and Director of the Southwestern Academic Limb Salvage Alliance (SALSA) at Keck School of Medicine of University of Southern California (USC), reported on the first results of a novel phase 2 study of gene therapy to heal wounds and reduce amputations in people with vascular disease at the International... Continue Reading →

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Two-Stage Gene Therapy (VEGF, HGF and ANG1 Plasmids) as Adjunctive Therapy in the Treatment of Critical Lower Limb Ischemia in Diabetic Foot Syndrome #ActAgainstAmputation #DiabeticFoot @ALPSlimb

It's superb work from our Polish colleagues. One of the most serious problems in people with diabetes is diabetic foot syndrome. Due to the peripheral location of atherosclerotic lesions in the arterial system of the lower extremities, endovascular treatment plays a dominant role. However, carrying out these procedures is not always possible and does not... Continue Reading →

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