Tag: Imaging

Imaging Infected Bone: WBC SPECT/CT vs. MRI in Diabetic Foot Osteomyelitis #ActAgainstAmputation

Our colleagues Larry Lavery and Andrew Crisologo, alongside lead author Orhan Öz, have published a significant prospective study in Diabetologia. Their work tackles one of the most difficult challenges in limb preservation: accurately diagnosing diabetic foot osteomyelitis (DFO) and, crucially, knowing when the infection is actually gone. The Challenge of the "Gold Standard" While bone... Continue Reading →

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A 3D Panoramic View Into the Body: Introducing RUS-PAT Imaging #ActAgainstAmputation @Caltech @USC_Vascular @NeurosurgeryUSC @KeckSchool_USC @USC @NatBME

Our colleagues at Caltech and USC Vascular Surgery and Neurosurgery, including Lihong Wang, Charles Liu, Tze Woei Tan, and Jonathan Russin, have unveiled a major leap in medical imaging. Published in Nature Biomedical Engineering, the team introduces Hybrid Rotational Ultrasound and Photoacoustic Tomography (RUS-PAT). Think of it as a high-speed, 3D panoramic camera for our... Continue Reading →

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🩸 PET Scans Reveal Localized Hyper-Perfusion in Diabetic Foot Ulcers #ActAgainstAmputation

Understanding the Vascular Dynamics of DFU Healing and Pathology A recent study published in the Journal of Clinical Medicine by Christensen et al. (2025) utilized Oxygen-15 Labeled Water PET imaging to investigate resting skeletal muscle perfusion in patients with Type 2 Diabetes Mellitus (T2DM) and diabetic foot ulcers (DFUs), comparing them to healthy controls. This... Continue Reading →

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MRI Monitoring in Charcot Foot: Valuable Insight or Victim of Modern Imaging Technology? #VOMIT #ActAgainstAmputation #CharcotArthropathy

Our colleagues from Lund, Sweden, have just added a valuable new data point to a growing conversation about the role—and risks—of imaging in Charcot foot care. Their retrospective cohort study, published in the Journal of Foot and Ankle Research, analyzed 143 Charcot events in 122 individuals, comparing those who were monitored using follow-up MRI with those... Continue Reading →

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Current and Future Directions in Fluorescence Imaging Guided Debridement #ActAgainstAmputation #Diagnostics #Theragnostics @ResearchatUSC @USC_vascular @keckschool_usc

Advancements in Chronic Wound Management Chronic wounds, such as diabetic foot ulcers (DFUs), present a significant challenge in medical practice due to their susceptibility to infection and the subsequent risk of amputation. Traditional methods of detecting bacterial loads in wounds rely on costly and time-consuming lab work, which often delays treatment. However, recent advancements in... Continue Reading →

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Understanding Muscle Quality and Function in Diabetic Peripheral Neuropathy: Insights from Foot-Level Computed Tomography #ActAgainstAmputation #DiabeticFoot

June 2024 Diabetic Peripheral Neuropathy (DPN) is a prevalent complication among individuals with diabetes, affecting nearly half of this population and significantly impacting foot function and overall quality of life. Recent research led by Emilia M. Kaszyk, Mary Hastings, Mike Muller, and colleagues from the Washington University School of Medicine has utilized advanced imaging techniques... Continue Reading →

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Harnessing AI in Diabetic Foot Disease: A Leap into 3D Imaging

Harnessing AI in Diabetic Foot Disease: A Leap into 3D Imaging Diabetic foot disease (DFD) is a serious complication of diabetes, often leading to lower limb amputations. With the global prevalence of diabetes on the rise, the urgency to improve early detection and management of DFD has never been greater. A recent systematic review by... Continue Reading →

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Diabetic Foot Ulcer Imaging: An Overview and Future Directions #C2SHiP #ActAgainstAmputation #Imaging #Diabetes #DiabeticFoot #Diagnostics

This from our combined team from FIU, UCSF, and USC led by Anu Godavarty Diabetic foot ulcers (DFUs) affect one in every three people with diabetes. Imaging plays a vital role in objectively complementing the gold-standard visual yet subjective clinical assessments of DFUs during the wound treatment process. Herein, an overview of the various imaging... Continue Reading →

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Combined evaluation of blood flow and tissue perfusion in diabetic feet by intra-arterial dynamic 4DCT imaging #ActAgainstAmputation #DiabeticFoot #Radiology

Fascinating continued work from our Belgian colleagues. Critical limb ischemia is associated with high mortality and major amputations. Intra-arterial digital subtraction angiography (IADSA) has been the reference standard but has some shortcomings including the two-dimensional projection and the lack of tissue perfusion information. The aim of this exploratory study is to examine four-dimensional computed tomography... Continue Reading →

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Preliminary evaluation of dual-energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis

Preliminary evaluation of dual‐energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis Great work as usual from our Dutch compatriots Objectives The purpose of this study is to evaluate the value of dual-energy CT (DECT) with virtual non-calcium (VNCa) in quantitatively assessing the presence of bone marrow... Continue Reading →

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