A terrific review by Rome’s Serini and Calviello Long-chain Omega-3 polyunsaturated fatty acids (Omega-3 PUFAs) are widely recognized as powerful negative regulators of acute inflammation. However, the precise role exerted by these dietary compounds during the healing process is still largely unknown, and there is increasing interest in understanding their specific effects on the implicated […]Read More New Insights on the Effects of Dietary Omega‐3 Fatty Acids on Impaired Skin Healing in DFU and VLU #DiabeticFoot #Wound Healing
A great review from Queensland that should help put some of the confusing M1-M2 phenotype story into sharper relief. Skin Wound Healing: Normal Macrophage Function and Macrophage Dysfunction in Diabetic Wounds Abstract: Macrophages play a prominent role in wound healing. In the early stages, they promote inflammation and remove pathogens, wound debris, and cells that […]Read More Mixed up Macrophages: M1/M2 Dysregulation in Diabetic Foot Ulcers
The Thermo-Pressure Concept: A New Model in Diabetic Foot Risk Stratification This from our Maltese SALSAmigos, Perren and coworkers Abstract: Elevated foot pressure and high temperatures have been proposed as predictive factors for diabetic foot ulceration; however, on their own, their predictive value is still questionable. This pilot study hypothesized that combining these two measurements […]Read More The Thermo-Pressure Concept: A New Model in Diabetic Foot Risk Stratification
Compelling work from Fields at Scripps, Florida suggest that we may be entering a new era of selective MMP inhibitors that may have profound implications from wound healing to cancer therapy. Buckle up!Read More The Rebirth of Matrix Metalloproteinase (MMP) Inhibitors?