“Spooky Action at a Distance”: The Most Comprehensive Review Yet of Physiologic Neuromodulation for Limb Preservation #ActAgainstAmputation #Neuromodulation #SpinalCordStimulation #CLTI @BurnsTrauma @KeckSchool_USC @ResearchatUSC @USC

Our new paper in Burns and Trauma presents the most comprehensive review yet of spooky action at a distance therapies for diabetic limb preservation โ€” from spinal cord stimulation and splenic ultrasound to remote ischemic conditioning and tibial transport. Five modalities, three mechanistic pathways, one shared destination: tissue repair at a distance.

Dosing Walking Like a Drug: An AI Chatbot for Diabetic Foot Remission Following Limb Reconstruction #ActAgainstAmputation #DiabeticFoot #Remission #AI #Chatbot @SensorsMDPI @KeckSchool_USC @ALPSLimb @USC_Vascular

A new protocol paper in Sensors describes a chatbot that doses walking like a drug for patients in diabetic foot remission.

You Are What You Eat โ€” And That’s Pretty Inflammatory: A New Composite Biomarker for DFU Risk #ActAgainstAmputation #DFU #Nutrition @ALPSLimb

A novel inflammation-nutrition biomarker โ€” the neutrophil percentage-to-albumin ratio (NPAR) โ€” shows strong association with diabetic foot ulcer risk in a 1,002-patient study from Xi'an, China, reinforcing that what patients eat and how they inflame are inseparable in the diabetic foot.

25 Years of Plantar Pressure Research in #DiabeticFoot Ulcers: A Bibliometric Deep Dive @MDABORATORY #ActAgainstAmputation

A new bibliometric analysis from Wei and colleagues at Capital Medical University in Beijing maps 25 years (2000โ€“2024) of global research on plantar pressure and diabetic foot ulcers โ€” over 2,100 publications indexed in the Web of Science Core Collection. The findings tell a story that will feel familiar to many of us who have... Continue Reading →

Limb Preservation: The Global State of Play in 2026 — Keynote at ADFA’s Inaugural Meeting in Paris #ActAgainstAmputation @ALPSLimb #DiabeticFoot #LimbPreservation #Paris

Honored to deliver the keynote at the inaugural meeting of ADFA in Paris.

Control-Alt-Delete: Rebooting the Chronic Wound #ActAgainstAmputation #DFU #WoundHealing @ALPSLimb @KeckSchool_USC @USC_Vascular

Chronic wounds are biological computers stuck in a boot loop. Sharp debridement is Control-Alt-Delete โ€” the histological reboot that converts a chronic wound back into an acute one. Only then can you run the apps.

One in Three: What the First Year of DFU Remission Really Looks Like #ActAgainstAmputation @DiabetologyMdpi @ALPSLimb @KeckSchool_USC #DFU #Remission #Survivorship

A new systematic review finds that roughly one in three adults in remission after a healed diabetic foot ulcer develop a recurrent ulcer within 12 months โ€” a risk comparable to several common cancers. Healing is the beginning of the next chapter, not the end of the story.

Nearly a Million Words Later: What 17 Years of DiabeticFootOnline Look Like in a Word Cloud #ActAgainstAmputation @ALPSlimb

Nearly a Million Words Later: What 17 Years of DiabeticFootOnline Look Like in a Word Cloud I recently did something I probably should have done a long time ago. I pointed an AI at every single blog post on this siteโ€”all 3,835 of themโ€”and asked it to show me what nearly two decades of writing... Continue Reading →

Marrying Data with Common Sense: Is it Safe to Amputate a Toe at Bedside in an Inpatient Unit? #ActAgainstAmputation

In the world of diabetic foot care, we often find ourselves at a crossroads when a patient presents with isolated toe necrosis. Traditionally, this meant an automatic ticket to the operating room (OR) for a conventional amputation surgery (CAS). But as operating rooms become increasingly crowded and resources stretched thin, we have to ask: is... Continue Reading →

Another Frontier in Limb Preservation: Automated Periosteal Distraction? #ActAgainstAmputation #WoundHealing

In the journey to eliminate preventable amputations, we continue to look for ways to harness the bodyโ€™s own regenerative potential. Our latest brief communication describes a significant โ€œfirstโ€ in the field: the application of fully automated tibial periosteal distraction (PD) for limb preservation. While it has long been understood that applying controlled โ€œtension-stressโ€ to tissue... Continue Reading →

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