A Foot Ulcer Is a Whole-Body Diagnosis: New 5698 Patient Cohort Puts DFU Survival Back in the Cancer Conversation — But There’s Hope #DiabeticFoot #ActAgainstAmputation #ToeandFlow

A new 5,698-patient real-world cohort from Valladolid (Del Río-Solá et al., Adv Wound Care 2026) reports 61.8% five-year survival overall, falling to 32.1% after major amputation — and concludes the diabetic foot ulcer should be treated as a marker of advanced systemic disease, not an isolated wound. The newest entry in a fifteen-year line of evidence putting DFU mortality squarely in the cancer conversation.

Two thirds of high-level amputations in those with PAD received low-intensity assessment. Here are the details on how to #ActAgainstAmputation

Using Medicare claims data from over 33,000 beneficiaries between 2016 and 2019, the investigators identified nearly 8,000 patients who underwent a major lower extremity amputation due to chronic limb-threatening ischemia (CLTI). Their findings offer a window into the continuum—or lack thereof—of care before amputation, and the inequities that pervade it. Among their key findings: 63%... Continue Reading →

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