Digging Deep vs. Scratching the Surface: Is the “Gold Standard” for DFO Biopsies Losing its Shine? #ActAgainstAmputation #Infection #Osteomyelitis

Friends, we have some serious dogma-busting data to discuss today. For as long as most of us have been in the limb salvage game, the percutaneous bone biopsy has been preached as the absolute "Gold Standard" for guiding antibiotic therapy in Diabetic Foot Osteomyelitis (DFO). The logic was sound: if you want to know whatโ€™s... Continue Reading →

Remember to Take Your Vitamins (and Sprinkle Them on Biofilm)ย ๐Ÿงซย A Look at Vitamin C #ActAgainstAmputation

Weโ€™ve long been told to take our vitaminsโ€”but recent research suggests we might also want to โ€œprescribeโ€ them directly to our most persistent microbial adversaries. A striking 2025 study published in BMC Microbiology reveals that vitamin C (sodium ascorbate) may do more than bolster immune function: it can weaken drug-resistant bacterial biofilms and restore the efficacy of... Continue Reading →

Harnessing Probiotics: A Leap Towards Managing Diabetic Foot Infections?

Harnessing Probiotics: A Leap Towards Alleviating Diabetic Foot Infections In the battle against diabetic foot infections, a beacon of hope emerges from the heart of Baghdad. A recent manuscript published in the Iraqi Journal of Science, penned by Haneen Majid Abdulkareem AlAsadi and Khalid Jaber Kadhum Luti from the Department of Biotechnology, College of Science,... Continue Reading →

The Use of Point-of Care Bacterial Autofluorescence Imaging in the Management of Diabetic Foot Ulcers: A Pilot Randomized Controlled Trialย #Diagnostics #Theragnostics

Important work from our SALSAmigos in Leeds. We see a slow and steady march toward companion diagnostics for our patients. Here we see fluorescence-guided debridement as an example of this. OBJECTIVE To estimate comparative healing rates and decision-making associated with the use of bacterial autofluorescence imaging in the management of diabetic foot ulcers (DFUs). RESEARCH... Continue Reading →

The microbiology of diabetic foot infections: a meta-analysis

The microbiology of diabetic foot infections: a meta-analysisExcellent work from MacDonald and coworkers from Edinburgh. The microbiology of diabetic foot infections: a meta-analysis Background: Diabetic foot ulcers are a common complication of poorly controlled diabetes and often become infected, termed diabetic foot infection. There have been numerous studies of the microbiology of diabetic foot infec-... Continue Reading →

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