Tag: moleculight

The Use of Point-of Care Bacterial Autofluorescence Imaging in the Management of Diabetic Foot Ulcers: A Pilot Randomized Controlled Trial #Diagnostics #Theragnostics

Important work from our SALSAmigos in Leeds. We see a slow and steady march toward companion diagnostics for our patients. Here we see fluorescence-guided debridement as an example of this. OBJECTIVE To estimate comparative healing rates and decision-making associated with the use of bacterial autofluorescence imaging in the management of diabetic foot ulcers (DFUs). RESEARCH... Continue Reading →

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Skin autofluorescence for non-enzymatic glycation end products in Diabetic Foot Ulcers (DFUs)- A meta analysis

Continued efforts to create companion diagnostics and theragnostics to help us measure what we manage and predict DFU risk. Imagine diagnosing "friable" tissue and then doing something about it?! Objective: Skin autofluorescence (SAF) has been suggested as a novel and noninvasive technique for assessing tissue accumulation of advanced glycation end products in diabetes and related complications.... Continue Reading →

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Diagnostic Accuracy of Point-of-Care Fluorescence Imaging for the Detection of Bacterial Burden in Wounds

This excellent work from Le and coworkers strongly suggests that using a point of care diagnostic device (Moleculight) can identify elevated bacterial load and influence medical decision making. Objective: High bacterial load contributes to chronicity of wounds and is diagnosed based on assessment of clinical signs and symptoms (CSS) of infection, but these characteristics are poor... Continue Reading →

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A microbial-load-guided debridement decision tree using bacterial fluorescence imaging #DiabeticFoot #ActAgainstAmputation

Strong concept from Cole and Coe. One can see the future of theragnostic-driven care in works like this. Use of a bacterial fluorescence imaging system to target wound debridement and accelerate healing: a pilot study Objective: Optimal wound-bed preparation consists of regular debridement to remove devitalised tissues, reduce bacterial load, and to establish an environment... Continue Reading →

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