Implementation of corneal confocal microscopy for screening and early detection of diabetic neuropathy in primary care alongside retinopathy #screening: Results from a feasibility study #DiabeticFoot @ALPSlimb

Continued strong work from our friends and colleagues making the link between the eyes and the sole Objective: Screening for diabetic peripheral neuropathy (DPN) is essential for early detection and timely intervention. Quantitative assessment of small nerve fiber damage is key to the early diagnosis and assessment of its progression. Corneal confocal microscopy (CCM) is a... Continue Reading →

Diabetic Peripheral Neuropathy Associated with Foot Ulcer: One of a Kind #ActAgainstAmputation #WoundHealing

Diabetic Peripheral Neuropathy Associated with Foot Ulcer: One of a Kind Compelling and insightful work from Chandan Sen and coworkers. Diabetic Peripheral Neuropathy Associated with Foot Ulcer: One of a Kind Significance: Diabetic peripheral neuropathy (DPN) associated with a diabetic foot ulcer (DFU) is likely to be complicated with critical factors such as biofilm infection... Continue Reading →

Gut Microbiota and Complications of Type-2 Diabetes

Gut Microbiota and Complications of Type-2 Diabetes The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance. Uncontrolled diabetes can lead to serious health consequences such as impaired kidney function, blindness, stroke, myocardial infarction and lower limb amputation.... Continue Reading →

Diabetic peripheral neuropathy linked to cognitive decline in type 2 diabetes

Diabetic peripheral neuropathy is associated with a decline in cognition for people with type 2 diabetes, according to study findings published in the Journal of Diabetes and its Complications. In findings from the Glycemia Reduction Approaches in Diabetes Study (GRADE), diabetic peripheral neuropathy was associated with worse results in cognitive tests, but no association was found with... Continue Reading →

Screening, diagnosis and management of diabetic sensorimotor polyneuropathy in clinical practice: International expert consensus recommendations #Neuropathy #DiabeticFoot #PDN #ActAgainstAmputation

Great work by an all-star consensus panel with practical recommendations. Diabetic sensorimotor polyneuropathy (DSPN) affects around one third of people with diabetes and accounts for considerable morbidity, increased risk of mortality, reduced quality of life, and increased health care costs resulting particularly from neuropathic pain and foot ulcers. Painful DSPN is encountered in 13-26% of... Continue Reading →

Diabetic Foot in Mouth Disease?

Yet more data to support the contention that different matrices are deleteriously and similarly affected by this silent sinister syndrome Proportion and severity of periodontitis and correlation of periodontal inflamed surface area with glycemic status in type 2 diabetic neuropathy patients with and without diabetic foot Background The association between diabetic neuropathy with and without... Continue Reading →

Validity and Reliability of a Vibration-Based Cell Phone in Detecting Peripheral Neuropathy among Patients with a Risk of Diabetic Foot Ulcer

After describing this concept some years ago, we're so happy to see this kind of idea finally be validated! Congratulations to Jasmin and coworkers for this effort that might help bring semi-quantitative nerve testing out into the community. The aim of this study was to determine the validity and reliability of a vibration-based cell phone... Continue Reading →

Telemedicine and the Foot Selfie helped providers deliver diabetic foot care during the pandemic @amdiabetesassn @apma @usc @usc_vascular @umich #ADA2021 @alpslimb #FootSelfie

Podiatric Surgeons Dr. Shin of USC and Brian Schmidt of University of MIchigan are front and center at this year’s end American Diabetes Association. For people with diabetic foot complications, access to care and regular physical examinations are crucial to achieving good outcomes and avoiding hospitalizations. Both were a challenge in 2020, especially during the... Continue Reading →

Cutaneous Innervation in Impaired Diabetic Wound Healing

From Nowak and coworkers at Northwestern. Type 2 diabetes (T2D) is associated with several potential comorbidities, among them impaired wound healing, chronic ulcerations, and the requirement for lower extremity amputation. Disease-associated abnormal cellular responses, infection, immunological and microvascular dysfunction, and peripheral neuropathy are implicated in the pathogenesis of the wound healing impairment and the diabetic... Continue Reading →

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