Gut Microbiota and Complications of Type-2 Diabetes

Gut Microbiota and Complications of Type-2 Diabetes The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance. Uncontrolled diabetes can lead to serious health consequences such as impaired kidney function, blindness, stroke, myocardial infarction and lower limb amputation. […]

Read More Gut Microbiota and Complications of Type-2 Diabetes

Diabetic peripheral neuropathy linked to cognitive decline in type 2 diabetes

Diabetic peripheral neuropathy is associated with a decline in cognition for people with type 2 diabetes, according to study findings published in the Journal of Diabetes and its Complications. In findings from the Glycemia Reduction Approaches in Diabetes Study (GRADE), diabetic peripheral neuropathy was associated with worse results in cognitive tests, but no association was found with […]

Read More Diabetic peripheral neuropathy linked to cognitive decline in type 2 diabetes

Screening, diagnosis and management of diabetic sensorimotor polyneuropathy in clinical practice: International expert consensus recommendations #Neuropathy #DiabeticFoot #PDN #ActAgainstAmputation

Great work by an all-star consensus panel with practical recommendations. Diabetic sensorimotor polyneuropathy (DSPN) affects around one third of people with diabetes and accounts for considerable morbidity, increased risk of mortality, reduced quality of life, and increased health care costs resulting particularly from neuropathic pain and foot ulcers. Painful DSPN is encountered in 13-26% of […]

Read More Screening, diagnosis and management of diabetic sensorimotor polyneuropathy in clinical practice: International expert consensus recommendations #Neuropathy #DiabeticFoot #PDN #ActAgainstAmputation

Diabetic Foot in Mouth Disease?

Yet more data to support the contention that different matrices are deleteriously and similarly affected by this silent sinister syndrome Proportion and severity of periodontitis and correlation of periodontal inflamed surface area with glycemic status in type 2 diabetic neuropathy patients with and without diabetic foot Background The association between diabetic neuropathy with and without […]

Read More Diabetic Foot in Mouth Disease?

Validity and Reliability of a Vibration-Based Cell Phone in Detecting Peripheral Neuropathy among Patients with a Risk of Diabetic Foot Ulcer

After describing this concept some years ago, we’re so happy to see this kind of idea finally be validated! Congratulations to Jasmin and coworkers for this effort that might help bring semi-quantitative nerve testing out into the community. The aim of this study was to determine the validity and reliability of a vibration-based cell phone […]

Read More Validity and Reliability of a Vibration-Based Cell Phone in Detecting Peripheral Neuropathy among Patients with a Risk of Diabetic Foot Ulcer

Telemedicine and the Foot Selfie helped providers deliver diabetic foot care during the pandemic @amdiabetesassn @apma @usc @usc_vascular @umich #ADA2021 @alpslimb #FootSelfie

Podiatric Surgeons Dr. Shin of USC and Brian Schmidt of University of MIchigan are front and center at this year’s end American Diabetes Association. For people with diabetic foot complications, access to care and regular physical examinations are crucial to achieving good outcomes and avoiding hospitalizations. Both were a challenge in 2020, especially during the […]

Read More Telemedicine and the Foot Selfie helped providers deliver diabetic foot care during the pandemic @amdiabetesassn @apma @usc @usc_vascular @umich #ADA2021 @alpslimb #FootSelfie

Cutaneous Innervation in Impaired Diabetic Wound Healing

From Nowak and coworkers at Northwestern. Type 2 diabetes (T2D) is associated with several potential comorbidities, among them impaired wound healing, chronic ulcerations, and the requirement for lower extremity amputation. Disease-associated abnormal cellular responses, infection, immunological and microvascular dysfunction, and peripheral neuropathy are implicated in the pathogenesis of the wound healing impairment and the diabetic […]

Read More Cutaneous Innervation in Impaired Diabetic Wound Healing

Effect of High-frequency Spinal Cord Stimulation in Patients With Painful Diabetic #Neuropathy: A Randomized Clinical Trial @JAMANeuro

Intriguing report from Petersen and coworkers for a common, complex and costly condition. Importance  Many patients with diabetic peripheral neuropathy experience chronic pain and inadequate relief despite best available medical treatments. Objective  To determine whether 10-kHz spinal cord stimulation (SCS) improves outcomes for patients with refractory painful diabetic neuropathy (PDN). Design, Setting, and Participants  The prospective, multicenter, open-label […]

Read More Effect of High-frequency Spinal Cord Stimulation in Patients With Painful Diabetic #Neuropathy: A Randomized Clinical Trial @JAMANeuro

Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults @annalsofIM @CaitlinWHicks #PeripheralNeuropathy

Important work from Hicks and coworkers from Hopkins. Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults Background: Growing evidence indicates that peripheral neuropathy (PN) is common even in the absence of diabetes. How- ever, the clinical sequelae of PN have not been quantified in the general population. Objective: To assess the associations of […]

Read More Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults @annalsofIM @CaitlinWHicks #PeripheralNeuropathy