Screening, diagnosis and management of diabetic sensorimotor polyneuropathy in clinical practice: International expert consensus recommendations #Neuropathy #DiabeticFoot #PDN #ActAgainstAmputation

Great work by an all-star consensus panel with practical recommendations. Diabetic sensorimotor polyneuropathy (DSPN) affects around one third of people with diabetes and accounts for considerable morbidity, increased risk of mortality, reduced quality of life, and increased health care costs resulting particularly from neuropathic pain and foot ulcers. Painful DSPN is encountered in 13-26% of […]

Read More Screening, diagnosis and management of diabetic sensorimotor polyneuropathy in clinical practice: International expert consensus recommendations #Neuropathy #DiabeticFoot #PDN #ActAgainstAmputation

Diabetic Foot in Mouth Disease?

Yet more data to support the contention that different matrices are deleteriously and similarly affected by this silent sinister syndrome Proportion and severity of periodontitis and correlation of periodontal inflamed surface area with glycemic status in type 2 diabetic neuropathy patients with and without diabetic foot Background The association between diabetic neuropathy with and without […]

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Validity and Reliability of a Vibration-Based Cell Phone in Detecting Peripheral Neuropathy among Patients with a Risk of Diabetic Foot Ulcer

After describing this concept some years ago, we’re so happy to see this kind of idea finally be validated! Congratulations to Jasmin and coworkers for this effort that might help bring semi-quantitative nerve testing out into the community. The aim of this study was to determine the validity and reliability of a vibration-based cell phone […]

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Telemedicine and the Foot Selfie helped providers deliver diabetic foot care during the pandemic @amdiabetesassn @apma @usc @usc_vascular @umich #ADA2021 @alpslimb #FootSelfie

Podiatric Surgeons Dr. Shin of USC and Brian Schmidt of University of MIchigan are front and center at this year’s end American Diabetes Association. For people with diabetic foot complications, access to care and regular physical examinations are crucial to achieving good outcomes and avoiding hospitalizations. Both were a challenge in 2020, especially during the […]

Read More Telemedicine and the Foot Selfie helped providers deliver diabetic foot care during the pandemic @amdiabetesassn @apma @usc @usc_vascular @umich #ADA2021 @alpslimb #FootSelfie

Cutaneous Innervation in Impaired Diabetic Wound Healing

From Nowak and coworkers at Northwestern. Type 2 diabetes (T2D) is associated with several potential comorbidities, among them impaired wound healing, chronic ulcerations, and the requirement for lower extremity amputation. Disease-associated abnormal cellular responses, infection, immunological and microvascular dysfunction, and peripheral neuropathy are implicated in the pathogenesis of the wound healing impairment and the diabetic […]

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Effect of High-frequency Spinal Cord Stimulation in Patients With Painful Diabetic #Neuropathy: A Randomized Clinical Trial @JAMANeuro

Intriguing report from Petersen and coworkers for a common, complex and costly condition. Importance  Many patients with diabetic peripheral neuropathy experience chronic pain and inadequate relief despite best available medical treatments. Objective  To determine whether 10-kHz spinal cord stimulation (SCS) improves outcomes for patients with refractory painful diabetic neuropathy (PDN). Design, Setting, and Participants  The prospective, multicenter, open-label […]

Read More Effect of High-frequency Spinal Cord Stimulation in Patients With Painful Diabetic #Neuropathy: A Randomized Clinical Trial @JAMANeuro

Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults @annalsofIM @CaitlinWHicks #PeripheralNeuropathy

Important work from Hicks and coworkers from Hopkins. Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults Background: Growing evidence indicates that peripheral neuropathy (PN) is common even in the absence of diabetes. How- ever, the clinical sequelae of PN have not been quantified in the general population. Objective: To assess the associations of […]

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Does Normalizing Vitamin B12 Improve Signs and Symptoms of Neuropathy? Results of a One-Year Randomized Controlled Trial

Intriguing data from Thessaloniki, Tubingen and Sheffield seem to lend more credence to normalizing methylcobalamin (Vitamin B12) in people with diabetic neuropathy. Aim: To investigate the effect of normalizing vitamin B12 (B12) levels with oral B12 (methylcobalamin) 1000 μg/day for one year in patients with diabetic neuropathy (DN). Patients and methods: In this prospective, double-blind, placebo-controlled trial, […]

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Corneal confocal microscopy identifies small fibre damage and progression of diabetic neuropathy @SciReports @WCMQatar

Important work from our long-time SALSAmigo, Rayaz Malik and team. Corneal confocal microscopy identifies small fibre damage and progression of diabetic neuropathy published in Nature Scientific Reports. Corneal confocal microscopy identifies small fibre damage and progression of diabetic neuropathy Accurately quantifying the progression of diabetic peripheral neuropathy is key to identify individuals who will progress […]

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