Negative Pressure Wound Therapy Promotes Wound Healing by Inhibiting Inflammation in Diabetic Foot Wounds: A Role for NOD1 Receptor

Yet more insight into the mechanism of action of NPWT. From Wang and coworkers in the International Journal of Lower Extremity Wounds (IJLEW). Aims: Diabetic foot results in frequent amputation and quality-of-life reduction in diabetes population. These lesions are featured by a prolonged and exaggerated inflammation with a significant impairment in local bacterial invasion. Negative pressure... Continue Reading →

Flap monitoring with incisional negative pressure wound therapy (#NPWT) in diabetic foot patients #ActAgainstAmputation

Clever work from Park and Park in Scientific Reports Flap monitoring with incisional negative pressure wound therapy (NPWT) in diabetic foot patients Various types of flaps are considered as reconstructive options for patients with diabetic foot ulcer. However, flap reconstruction for diabetic foot ulcer treatment is particularly challenging becauseof the relatively limited collateral perfusion in... Continue Reading →

Proteomics changes after negative pressure wound therapy in diabetic foot ulcers

Excellent continued efforts in elucidating the role that perturbation of the wound matrix (via NPWT) has on angiogenesis, healing and regeneration. = Label‑free quantitative mass spectrometry was used to analyze the differences in the granulation tissue protein expression profiles of patients with diabetic foot ulcers (DFUs) before and after negative‑pressure wound therapy (NPWT) to understand... Continue Reading →

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