Excellent work from Zhang and coworkers. Screenshot Screenshot Negative pressure injury is one of the auxiliary methods of treating diabetes foot ulcers. It has been shown to be superior to conventional techniques in randomized controlled trials (RCTs). Nevertheless, the results of observational research are still scarce. A systematic review of RCTs and observations was carried... Continue Reading →
Harnessing WhatsApp to Monitor Negative Pressure Wound Therapy
In the realm of diabetic foot ulcer (DFU) management, a recent study has shed light on the potential of WhatsApp, a popular instant messaging application, as a tool for monitoring wound progress. This innovative approach could revolutionize the way we manage DFUs, particularly in the context of telemedicine. The Burden of Diabetic Foot Ulcers Diabetic... Continue Reading →
Accelerating Diabetic Wound Healing: A Leap Through Mechano-Activated Cell Therapy #ActAgainstAmputation #WoundHealing #DiabeticFoot
This, ladies and gents, reminds me of the mechanism of action of negative pressure wound therapy-- matrix perturbation! In the relentless pursuit of groundbreaking solutions to address diabetic wound healing, a recent manuscript by Shou et al., unveils a promising stride in the realm of regenerative medicine. The collaborative research initiative led by our esteemed... Continue Reading →
Negative Pressure Wound Therapy Promotes Wound Healing by Inhibiting Inflammation in Diabetic Foot Wounds: A Role for NOD1 Receptor
Yet more insight into the mechanism of action of NPWT. From Wang and coworkers in the International Journal of Lower Extremity Wounds (IJLEW). Aims: Diabetic foot results in frequent amputation and quality-of-life reduction in diabetes population. These lesions are featured by a prolonged and exaggerated inflammation with a significant impairment in local bacterial invasion. Negative pressure... Continue Reading →
Flap monitoring with incisional negative pressure wound therapy (#NPWT) in diabetic foot patients #ActAgainstAmputation
Clever work from Park and Park in Scientific Reports Flap monitoring with incisional negative pressure wound therapy (NPWT) in diabetic foot patients Various types of flaps are considered as reconstructive options for patients with diabetic foot ulcer. However, flap reconstruction for diabetic foot ulcer treatment is particularly challenging becauseof the relatively limited collateral perfusion in... Continue Reading →
Proteomics changes after negative pressure wound therapy in diabetic foot ulcers
Excellent continued efforts in elucidating the role that perturbation of the wound matrix (via NPWT) has on angiogenesis, healing and regeneration. = Label‑free quantitative mass spectrometry was used to analyze the differences in the granulation tissue protein expression profiles of patients with diabetic foot ulcers (DFUs) before and after negative‑pressure wound therapy (NPWT) to understand... Continue Reading →