Bone Voyage: Navigating Updates in the Management of Bone and Joint Infections #Osteomyelitis #ActAgainstAmputation

Current Infectious Disease Reports Volume 27, Article Number 5 (2025) Published: 02 January 2025 Steering Toward Innovation in Bone and Joint Infection Management The management of bone and joint infections (BJIs) has undergone significant evolution, as highlighted in the latest review by Barbara A. Santevecchi, Kayihura Manigaba, and Lindsey M. Childs-Kean. Published in Current Infectious Disease... Continue Reading →

Amputation versus circular external fixation in the treatment of diabetic foot with osteomyelitis: a cost and quality-of-life analysis #ActAgainstAmputation

A recent study published in Therapeutic Advances in Endocrinology and Metabolism compares two approaches for managing diabetic foot with osteomyelitis: amputation versus circular external fixation (CEF). The research highlights a pressing issue in diabetes care, as Charcot foot—a severe complication involving infected ulcers—often leads to amputation, with five-year mortality rates reaching as high as 70%.... Continue Reading →

Does complete resection of infected bone improve clinical outcomes in patients with diabetic foot osteomyelitis #ActAgainstAmputation

Osteomyelitis in patients with diabetes presents significant clinical challenges, often leading to prolonged treatments and complex surgical decisions. A recent study by our long-time toemigo Lavery et al. (2024) published in The International Wound Journal delves into whether complete resection of infected bone improves outcomes in these patients. Screenshot Screenshot The study analyzed data from... Continue Reading →

New Study Highlights Prevalence and Treatment Challenges of Diabetic Sausage Toe #ActAgainstAmputation #Osteomyelitis #DiabeticFoot

New Study Highlights Prevalence and Treatment Challenges of Diabetic Sausage Toe A recent study led by Yammine et al. (2024) sheds light on the underrecognized condition known as the "diabetic sausage toe," a presentation of osteomyelitis (OM) in diabetic patients. This study, published in the International Wound Journal, emphasizes the prevalence, clinical characteristics, and treatment... Continue Reading →

Decoding Diabetic Foot Osteomyelitis: A Comparative Study of Biomarkers

In a recent study by Coye et al. (2023), with many of long-time SALSAmigos as coauthors , the effectiveness of C-reactive protein (CRP)/albumin, erythrocyte sedimentation rate (ESR)/albumin ratio, ESR, CRP, and albumin were evaluated to differentiate bone and soft tissue infection in persons with diabetes[1]. The study retrospectively evaluated 242 individuals admitted to the hospital... Continue Reading →

Comorbid status in patients with #osteomyelitis is associated with long-term incidence of extremity amputation #ActAgainstAmputation #Diabetes

Comorbid status in patients with osteomyelitis is associated with long- term incidence of extremity amputation The study by Schmidt et al. (2023) examines the long-term incidence of extremity amputation in osteomyelitis patients, emphasizing the impact of comorbidities. Key findings include: Diabetic patients had a 3.65-fold higher likelihood of lower extremity amputation. Male gender, Black race,... Continue Reading →

Bone Resection Versus Bone Curettage in Diabetic Foot Osteomyelitis: which is preferred? #ActAgainstAmputation #ALPSlimb

Diabetic foot osteomyelitis (DFO) requires effective management to expedite healing and mitigate complications. A recent study compared bone resection with bone curettage in treating DFO. Conducted from January 2017 to January 2022, the study retrospectively analyzed 31 patients' clinical records post-surgery. Results showcased shorter healing times in the resection group (mean: 5.70 ± 6.05 weeks)... Continue Reading →

Residual Osteomyelitis after Conservative Surgery for Diabetic Foot Infection Does Not Increase Recurrence Risk, Study Finds #Diabetes #DiabeticFoot #Osteomyelitis

Introduction:A recent study conducted by our colleagues from the Canary Islands, Aragon-Sanchez et al., investigated the association between residual osteomyelitis at the resection margin and the recurrence of diabetic foot infection. The researchers aimed to determine if positive bone margins, confirmed by microbiology and pathology, were linked to worse outcomes. The findings provide valuable insights... Continue Reading →

Preliminary evaluation of dual-energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis

Preliminary evaluation of dual‐energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis Great work as usual from our Dutch compatriots Objectives The purpose of this study is to evaluate the value of dual-energy CT (DECT) with virtual non-calcium (VNCa) in quantitatively assessing the presence of bone marrow... Continue Reading →

Level of 25-hydroxyvitamin D and vitamin D receptor in diabetic foot ulcer and factor associated with diabetic foot ulcers #ActAgainstAmputation @ALPSlimb

Tang and coworkers present these data. Bottom line: The study aimed to investigate the correlation between vitamin D deficiency and diabetic foot osteomyelitis (DFO) in patients with type 2 diabetes mellitus (T2DM) and diabetic foot ulcer (DFU). The levels of serum 25-hydroxyvitamin D [25(OH)VD] and vitamin D receptor (VDR) expression in wound margin tissues were... Continue Reading →

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