Inflammation, Lipids, and Limb Risk: New Clues from Two Cohorts #ActAgainstAmputation #PAD #VascularDisease #CLTI

Peripheral artery disease (PAD) is one of the most devastating complications of diabetesโ€”contributing to ischemic pain, functional decline, and, in severe cases, amputation. Despite its prevalence, early detection remains elusive, and clinicians continue to search for simple, reliable markers of risk. A new multicohort study led by Wang and colleagues now shines a spotlight on... Continue Reading →

New Study Projects 360 Million Cases of Peripheral Artery Disease by 2050, Driven by Metabolic Risk and Aging #ActAgainstAmputation @researchatusc @alpslimb #CLTI #PAD

FOR IMMEDIATE RELEASE July 8, 2025 New Study Projects 360 Million Cases of Peripheral Artery Disease by 2050, Driven by Metabolic Risk and Aging Proactive Prevention Could Avert One in Three Cases Chongqing, Los Angeles โ€” A landmark global study published today in Research (DOI: 10.34133/research.0702) projects a 220% increase in peripheral artery disease (PAD) cases worldwide by 2050,... Continue Reading →

Exploring New Frontiers in Peripheral Artery Disease Diagnosis: The Role of Dorsal Metatarsal Artery Indices #Diagnostics #CLTI #PAD #ActAgainstAmputation

Screenshot The realm of vascular health is continuously evolving, seeking more precise and reliable methods to diagnose and manage peripheral artery disease (PAD). A recent study by Ciuti et al., published in Diabetes Research and Clinical Practice, delves into the use of the resistive index (RI) and pulsatility index (PI) of the dorsal metatarsal artery... Continue Reading →

Modified Tibial Cortex Transverse Transport (TTT): Yet more reported data for limb preservation? #ActAgainstAmputation #DiabeticFoot

Diabetic foot ulcers (DFUs) are a significant global health concern, affecting a substantial number of individuals with diabetes. These ulcers often present challenges in achieving healing, leading to prolonged non-healing and, in some cases, necessitating amputation. However, a recent study by Liu et al. (2024) offers a promising new approach to managing DFUs[1]. The Study... Continue Reading →

Early Hemodynamic Improvement after Tibial Transport in the Diabetic Foot

The study by Liao et al. (2023) suggests significant differences in early hemodynamics after tibial transverse transport in patients with diabetic foot, focusing on those with nonarterial stenosis versus arterial stenosis. High-frequency color Doppler ultrasonography and laser Doppler flowmetry were used to assess changes. The study contributes to our understanding of diabetic foot treatment by... Continue Reading →

Intersocietal PAD guidelines on the Diabetic Foot #ActAgainstAmputation #IWGDF

Here is the link to the guidelines for peripheral artery disease in people with diabetes. Diabetes-related foot complications have become a major cause of morbidity and are implicated in most major and minor amputations globally. Approximately 50% of people with diabetes and a foot ulcer have peripheral artery disease (PAD) and the presence of PAD... Continue Reading →

Journal of the American Medical Association: Diabetic Foot Ulcers @JAMA_Current #ActAgainstAmputation #DiabeticFoot

From JAMA Armstrong, Tan, Boulton, and Bus, JAMA.ย 2023;330(1):62-75. doi:10.1001/jama.2023.10578 In diabetic foot disease, tissue loss,ischemia, and infection frequentlyoverlap. However, one is frequentlymore dominant than the other atdifferent times in the life cycle of anacute-on-chronic event. Here, theamount of tissue loss, ischemia, andfoot infection can be ordinally gradedto help predict outcome and assist incommunicating a plan... Continue Reading →

Evaluating the prognostic performance of bedside tests used for peripheral arterial disease diagnosis in the prediction of diabetic foot ulcer healing

Evaluating the prognostic performance of bedside tests used for peripheral arterial disease diagnosis in the prediction of diabetic foot ulcer healing - Great work from our colleagues from Imperial College, London. Evaluating the prognostic performance of bedside tests used for peripheral arterial disease diagnosis in the prediction of diabetic foot ulcer healing WHAT IS ALREADY... Continue Reading →

New Study Reveals Racial Disparities in Treatment and Outcomes for Patients with Peripheral Artery Disease ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC

FOR IMMEDIATE RELEASE New Study Reveals Racial Disparities in Treatment and Outcomes for Patients with Peripheral Artery Disease Los Angeles, CA - March 10, 2023 - Researchers at the University of Southern California (USC) have published a new study in the journal Advanced Therapeutics revealing significant disparities in the treatment and outcomes for patients with... Continue Reading →

Senescent Diabetic Foot Disease: Upstream comprehensive management of individuals with diabetes with multimorbidity and frailty to #ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC @VirginiePhD_POD @AeroMD

This manuscript from our combined Quebec/ Palermo / USC family. Virginie Blanchette, David G. Armstrong, Laura Drudi and Manfredi Rizzo This manuscript constitutes a commentary on: โ€œRetrospective cohort study of long-term outcomes and prognostic factors for survival after lower extremity amputation in patients with diabetesโ€ by Vuorlaakso et al. (2023). We aim to contribute to... Continue Reading →

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