The Crucial Role of pH in Healing Diabetic Foot Ulcers:

Screenshot Diabetic foot ulcers (DFUs) are a common and severe complication of diabetes, leading to significant morbidity and, in severe cases, amputation. The healing process of these ulcers is complex and can be hindered by various factors, including infection and poor blood circulation. A recent observational study conducted by Yiru Wang and colleagues at Huadong... Continue Reading →

Do diabetes-related foot ulcer wound fluid measures have clinical utility as biomarkers for healing? A systematic review @ALPSlimb #ActAgainstAmputation

This work from Longfield and coworkers from Stephen Twigg's unit further highlight the potential benefit of measuring what we manage. Objective: This study aimed to identify potential biomarkers reported in wound fluid of diabetes-related foot ulcers (DRFUs), and their ability to reflect current and prospective wound healing. Method: A systematic search was executed following the PRISMA methodology... Continue Reading →

A wound alkalinity measurement to predict non-healing wound outcomes: A literal litmus test #Diagnostics #Theragnostics #WoundHealiing #Diabetic Foot

Again, a literal litmus test to help guide therapy. From Senkowsky and coworkers in JWC More work can be found here and here and here and here (etc). Abstract Objective: As wound pH could influence wound healing rates, this study examined the alkalinity of the entire wound during patients' follow-up visits to predict the final non-healing... Continue Reading →

The effect of inflammation management on pH, temperature, and bacterial burden #ActAgainstAmputation #WoundHealing

Important work from Derwin and coworkers in Zena Moore's group. The aim of this feasibility study was to investigate the impact of inflammation management on wound pH, temperature, and bacterial burden, using the principles of TIME and Wound Bed Preparation. A quantitative non-comparative, prospective, descriptive observational design. Following ethical approval, 26 participants with 27 wounds... Continue Reading →

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