pMAC / Pedal Medial Arterial Calcification Score Yet more important work from our Toe- and Flowmigos @ UCSF. Objective: Pedal medial arterial calcification (pMAC) is associated with major amputation in patients with chronic limb-threatening ischemia (CLTI). We hypothesize that this association would be related to unresolved distal ischemia. We investigated relationships across pMAC score, hemodynamic change,... Continue Reading →