Get the Balance Right: How Much Pressure Is Too Much for the Diabetic Foot? #ActAgainstAmputation

When it comes to neuropathic (and likely neuroischemic) diabetic foot ulcers (DFUs), pressure and perfusion are often at odds. In an elegant study, Zhang and colleagues from Fudan University and Shanghai Jiao Tong University have quantified how the skinโ€™s microcirculation responds to physiologic, gait-like pressureโ€”and when that response begins to failย . ๐Ÿšถโ€โ™‚๏ธWalking the Line: Pressure... Continue Reading →

The Thermo-Pressure Concept: A New Model in Diabetic Foot Risk Stratification

The Thermo-Pressure Concept: A New Model in Diabetic Foot Risk Stratification This from our Maltese SALSAmigos, Perren and coworkers Abstract: Elevated foot pressure and high temperatures have been proposed as predictive factors for diabetic foot ulceration; however, on their own, their predictive value is still questionable. This pilot study hypothesized that combining these two measurements... Continue Reading →

Study: People with Diabetic Foot Ulcers Don’t Vasodilate after Pressure Challenge. A New Marker for Risk (and Treatment Target)?

Important new work from our Lyonnaise and German colleagues published in the journal Diabetes. Neurovascular response to pressure in patients with diabetic foot ulcer Julien Vouillarmet MD1, Audrey Josset-Lamaugarny2,3, Paul Michon MD1, Jean Louis Saumet MD, PhD2,3, Audrey Koitka-Weber PhD4,5, Samir Henni MD4, Berengere Fromy PhD2,3, Dominique Sigaudo-Roussel PhD2,3 Diabetic foot ulcer (DFU) is a... Continue Reading →

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