Association between elevated skin temperature of the foot callus and inflammatory marker in people with diabetes #ActAgainstAmputation #Diagnostic #Theragnostic #DiabeticFoot

Calluses are defined as “hyperkeratosis caused by excessive mechanical loading in particular areas” and can contribute to the development of diabetic foot ulcers(DFUs). Callus inflammation is a premonitory symptom of DFUs. To prevent DFUs, recent studies have recommended thermographic monitoring of foot skin temperature, which is recognized as a sign of skin inflammation. However, no... Continue Reading →

Effects of Special Therapeutic Footwear on the Prevention of #DiabeticFoot Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials @ALPSlimb #ActAgainstAmputation

This manuscript from Luo and coworkers provides an update on one of the most important interventions we can provide our patients. Objective: To reduce diabetic foot ulcer (DFU) occurrence or recurrence, diabetic therapeutic footwear is widely recommended in clinical practice for at-risk patients. However, the effectiveness of therapeutic footwear is controversial. Thus, we performed a systematic... Continue Reading →

Top 10 research priorities in diabetic foot ulcer prevention and care

Good work from Kumlien and coworkers published in Diabetic Medicine Aim: To establish outcomes of a priority setting partnership between participants with diabetes mellitus and clinicians to identify the top 10 research priorities for preventing and treating diabetic foot ulcers (DFUs).Methods: Due to the COVID-19 pandemic, the James Lind Alliance Priority Setting Partnership process was adapted into... Continue Reading →

Association between Preventive Podiatric Care and Outcomes of New Diabetic Foot Ulceration among Patients with End Stage Renal Disease @USC @KeckSchool_USC, @USC_Vascular @TzeWoeiTan @APMA @ALPSLIMB @VascularCures @VascularSVS

This was just presented by our team at the American Diabetes Association annual symposium. We're thrilled that Tze Woei Tan, lead author, was awarded the Marvin Levin Award for top abstract in its category. The study, the first of its kind, evaluated more than 50,000 patients. Those that received podiatric care prior to developing a... Continue Reading →

Intensive Diabetes Control Reduces Incidence of a Diabetic Foot Ulcer by 23%: DCCT @ALPSlimb #ActAgainstAmputation

Great work from Ed Boyko and coworkers who mined the Diabetes Control and Complications Trial (DCCT) for these golden data. Abstract Objective: Intensive glycemic control reduces the risk of kidney, retinal, and neurologic complications in type 1 diabetes (T1D), but whether it reduces the risk of lower-extremity complications is unknown. We examined whether former intensive versus... Continue Reading →

An explainable machine learning model for predicting in‐hospital amputation rate of patients with diabetic foot ulcer

Just published this past week by our collective Chongqing/Singapore/and local LA squad. Diabetic foot ulcer (DFU) is one of the most serious and alarming diabetic complications, which often leads to high amputation rates in diabetic patients. Machine learning is a part of the field of artificial intelligence, which can automatically learn models from data and... Continue Reading →

Pay For Performance Reduces Incident Ulceration, Amputation, Death in the Diabetic Foot: Nationwide Study

A key Taiwanese nationwide study suggests that focusing on quality can improve outcomes. See for yourself: A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes Highlights The nationwide population-base investigation unlinked vascular benefit of... Continue Reading →

Thermometry reduces risk for reucleration in remission– in patients who reduce their activity

Important work from Sicco Bus, et al. published in BMJ Diabetes This RCT (DIATEMP) suggests that it's not enough just to know that you've a preulcerative hot spot-- but you need to do something about it. In this case, patients were told to reduce activity. Effectiveness of at-home skin temperature monitoring in reducing the incidence... Continue Reading →

@CDCgov Analysis of Cost Effectiveness in #Diabetes: Hypertension Control and Foot Care top the list @alpslimb #DiabeticFoot #ActAgainstAmputation @apma

This superb report from Siegel and coworkers from the Centers for Disease Control and Prevention. OBJECTIVE To synthesize updated evidence on the cost-effectiveness (CE) of interventions to manage diabetes, its complications, and comorbidities. RESEARCH DESIGN AND METHODS We conducted a systematic literature review of studies from high-income countries evaluating the CE of diabetes management interventions recommended by... Continue Reading →

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