Tag: remission

An in vivo model for overloading-induced soft tissue injury #ActAgainstAmputation #DiabeticFoot #Theragnostics #Diagnostics @ALPSlimb @Staffsbiomech

Strong work from our Staffordshire colleagues Chatzistergos and Chockalingam who continue to help push the envelope in helping us collectively measure what we manage. An in vivo model for overloading-induced soft tissue injury This proof of concept study demonstrates that repetitive loading to the pain threshold can safely recreate overloading induced soft tissue damage and... Continue Reading →

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Custom-made footwear designed for indoor use increases short-term and long-term adherence in people with diabetes at high ulcer risk #ActAgainstAmputation #Shoes #DiabeticFoot @diabetesRC

Important work from our Dutch SALSAmigos. Can it help guide us to work with our patients to improve adherence and #ActAgainstAmputation? Renske Keukenkamp, Jaap J van Netten, Tessa E Busch-Westbroek, Sicco A BusCorrespondence to Dr Sicco A Bus; s.a.bus@amsterdamumc.nl Introduction To explore changes in footwear adherence following provision of custom-made indoor footwear in people with diabetes at high risk for plantar... Continue Reading →

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Is a Left-to-Right >2.2°C Difference a Valid Measurement to Predict Diabetic Foot Ulceration in People in Diabetic Foot Remision? #Thermometry

Terrific work from Featherson and coworkers lending further light on the role (and limitations) of thermometry/thermography in predicting reulceration in diabetic foot remission Monitoring foot skin temperatures at home have been shown to be effective at preventing the occurrence of diabetic foot ulcers. In this study, the construct validity of using >2.2°C difference between contralateral... Continue Reading →

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Thermometry reduces risk for reucleration in remission– in patients who reduce their activity

Important work from Sicco Bus, et al. published in BMJ Diabetes This RCT (DIATEMP) suggests that it's not enough just to know that you've a preulcerative hot spot-- but you need to do something about it. In this case, patients were told to reduce activity. Effectiveness of at-home skin temperature monitoring in reducing the incidence... Continue Reading →

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Development of a prediction model for foot ulcer recurrence in people with diabetes using easy-to-obtain clinical variables #Remission #DiabeticFoot #UlcerFreeDays #Thermometry

Here is important work from our long-time Dutch friends and colleagues. Bottom line: there are now key factors that can be inputted into models to predict (and therefore reduce) risk for reulceration in patients in diabetic foot remission. This is the first multivariate model we've seen include use of personal thermometry. Wouter B Aan de... Continue Reading →

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The effects of different accumulated pressure-time integral stimuli on plantar blood flow in people with diabetes mellitus #diabeticfoot

This study from Duan and coworkers. Bottom line: people with diabetes do not recover as rapidly following activity-- particularly following repetitive activity. It is yet more data to guide us in better dosing activity and predicting diabetic foot ulcers. The effects of different accumulated pressure-time integral stimuli on plantar blood flow in people with diabetes... Continue Reading →

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Lower extremity reamputation in people with diabetes: a systematic review and meta-analysis @ALPSlimb #ActAgainstAmputation @USC_vascular @apma @keckmedusc @DiabetesRC

Lower extremity reamputation in people with diabetes: a systematic reviewand meta-analysis This from Liu and our group evaluating the best available evidence on reamputation. The bottom line: 1 year reamputation: 19%, 5 year reamputation 37.1%, 5 year contralateral reamputation: 20.5%. No trend for improvement or worsening over the past 2 decades. Lower extremity reamputation in... Continue Reading →

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Poor sleep and hypoxemia may be associated with longer wound healing and more frequent ulcer recurrence in remission

Fascinating work from Chen and coworkers. Perhaps something else we need to focus on that we often acknowledge but frequently neglect! STUDY OBJECTIVES: Sleep-disordered breathing (SDB) is prevalent and associated with increased risk of morbidity and mortality. However, whether SDB has an adverse impact on wound healing in patients with diabetic foot ulcers (DFUs) is... Continue Reading →

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Guidelines for Return To Activity in Diabetic Foot Ulcer Remission #ToeFlowandGo @USC @RanchoResearchI @USC_Vascular #Healing

Here are the instructions we give our patients upon returning to prescriptive shoes / activity following healing of a diabetic foot ulcer, foot reconstruction or partial foot amputation in remission. Courtesy of our "Gomiga" Stephanie Woelfel and the team at USC Physical Therapy / PT Wound Care. Dosing Activity and Returning to Pre-Ulcer function in... Continue Reading →

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Preventing foot ulceration in diabetes: systematic review and meta-analyses of RCT data #DiabeticFoot #Remission #ActAgainstAmputation @Diabetologia

Strong work from Fay Crawford and team! Aims/hypothesis Foot ulceration is a serious complication for people with diabetes that results in high levels of morbidity for individuals and significant costs for health and social care systems. Nineteen systematic reviews of preventative interventions have been published, but none provides a reliable numerical summary of treatment effects.... Continue Reading →

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