Tag: repair regeneration replacement revisited

From Scar to Salamander? Adult Mice Regrow Amputated Digits After Sequential FGF2 → BMP2 #regeneration #amputation @NatureComms

Yu and colleagues from Ken Muneoka's group show that sequential FGF2 then BMP2 treatment flips an adult mouse digit amputation from fibrosis to regeneration — rebuilding the distal phalanx with a growth plate, plus a parallel response that regenerates a synovial joint complex with tendon, ligament, and a sesamoid-like bone. The regeneration-competent cells are already in our wound beds. We just have to learn what to say to them.

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When Noncommunicable Diseases Overtook the World: Where We Stand Today and a Peek into the Future #NCDs #Lancet

Probability of dying from a non communicable disease: Change between 2010 and 2020, worldwide For much of human history, infectious diseases, maternal and neonatal conditions, and nutritional deficiencies defined the leading edge of mortality. Plagues, diarrheal disease, and tuberculosis were the archetypal killers. By contrast, noncommunicable diseases (NCDs)—heart disease, cancer, diabetes, chronic lung disease—were rare,... Continue Reading →

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Repair, Regeneration, and Replacement—Redux: A Look into the Future of Medicine @USC @CalTech @UCSF @Rancho_ResearchI @UCLA

How Do We Delay Decay? In 2012, the Repair, Regeneration, and Replacement Revisited lecture posed a fundamental question: How do we delay the inevitable decline of the human body? Now, 13 years later, that question is more relevant than ever. With AI-driven health technologies, regenerative medicine, and bioengineered solutions, we stand at the edge of a new medical revolution. We revisit... Continue Reading →

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Watch: Repair, Regeneration and Replacement, Revisited

For those who have been asking, here is the video, now available on YouTube and iTunesU. https://youtu.be/HHoGZ4qZTfs here is a manuscript revisiting this 13 years later Repair, Regeneration, and Replacement, Revisited (Redux) Armstrong, et al, J Diab Sci Technology

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