Breakthrough treatments for wound healing @scienceadvances #ActAgainstAmputation @alpslimb

This manuscript from Freeman and coworkers Skin injuries across the body continue to disrupt everyday life for millions of patients and result in prolonged hospital stays, infection, and death. Advances in wound healing devices have improved clinical practice but have mainly focused on treating macroscale healing versus underlying microscale pathophysiology. Consensus is lacking on optimal... Continue Reading →

Chronic Wounds @DiseasePrimers @Nature

A magnum opus from Vince Falanga, Rosyln Isseroff, Athena Soulika, Marco Romanelli, Dave Margolis, Suzanne Kapp, Mark Granick, and Keith Harding. Chronic wounds Abstract | Chronic wounds are characterized by their inability to heal within an expected time frame and have emerged as an increasingly important clinical problem over the past several decades, owing to... Continue Reading →

A systematic review of outcome reporting for interventions to treat people with diabetic foot ulceration @robhinchliffe1 #ActAgainstAmputation #diabeticfoot

Superb review and recommendations from Dovell and coworkers Background Diabetic foot ulceration (DFU) is a challenging clinical problem that affects up to a quarter of patients with diabetes in their lifetime. An agreed set of outcomes for assessing treatments or interventions for DFU has not previously been considered. The aim of this study was to... Continue Reading →

Pharmacotherapy for Diabetic Foot Ulcers- Topical and Systemic

A superb technical review from our SALSAmigos Dixon and Edmonds from King's. Historically, there has been a scarcity of evidence-based topical therapy to hasten the healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged from multicentre, randomised, controlled trials. This article highlights those trials, and describes the current pharmacological management of the... Continue Reading →

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