The Global and Regional Burden of Diabetic Peripheral Neuropathy: A Call to Action #Neuropathy #Diabetes

A recent review article in Nature Reviews Neurology highlights the pressing global and regional burden of diabetic peripheral neuropathy (DPN), a condition that affects up to 50% of people with type 1 or type 2 diabetes. The article, authored by Savelieff et al., not only underscores the profound individual and socioeconomic toll of DPN but also calls... Continue Reading →

From a Spark to a Flame: The Evolution of Diabetic Foot Disease in the Last Two Decades #DiabeticFoot #ActAgainstAmputation

The Evolution of Diabetic Foot Disease Over the Past Generation Diabetes-related foot complications have long been a significant health concern, but recent research from our friends and colleagues-- international experts Marco Meloni, Alberto Piaggesi, and Luigi Uccioli offers new insights into the evolution of diabetic foot disease (DFD) over the past two decades. Their comprehensive... Continue Reading →

Thermometry in the Diabetic Foot: See The Results of A Bibliographic Analysis

A recent bibliographic review by Marina Faus Camarena and colleagues, published in the journal Sensors, provides an update on the use of infrared thermography for the early detection of diabetic foot complications[1]. This non-invasive diagnostic tool could revolutionize the way we approach diabetic foot care, offering a means to detect early-stage ulcers and potentially prevent... Continue Reading →

Breakthrough treatments for wound healing @scienceadvances #ActAgainstAmputation @alpslimb

This manuscript from Freeman and coworkers Skin injuries across the body continue to disrupt everyday life for millions of patients and result in prolonged hospital stays, infection, and death. Advances in wound healing devices have improved clinical practice but have mainly focused on treating macroscale healing versus underlying microscale pathophysiology. Consensus is lacking on optimal... Continue Reading →

Chronic Wounds @DiseasePrimers @Nature

A magnum opus from Vince Falanga, Rosyln Isseroff, Athena Soulika, Marco Romanelli, Dave Margolis, Suzanne Kapp, Mark Granick, and Keith Harding. Chronic wounds Abstract | Chronic wounds are characterized by their inability to heal within an expected time frame and have emerged as an increasingly important clinical problem over the past several decades, owing to... Continue Reading →

A systematic review of outcome reporting for interventions to treat people with diabetic foot ulceration @robhinchliffe1 #ActAgainstAmputation #diabeticfoot

Superb review and recommendations from Dovell and coworkers Background Diabetic foot ulceration (DFU) is a challenging clinical problem that affects up to a quarter of patients with diabetes in their lifetime. An agreed set of outcomes for assessing treatments or interventions for DFU has not previously been considered. The aim of this study was to... Continue Reading →

Pharmacotherapy for Diabetic Foot Ulcers- Topical and Systemic

A superb technical review from our SALSAmigos Dixon and Edmonds from King's. Historically, there has been a scarcity of evidence-based topical therapy to hasten the healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged from multicentre, randomised, controlled trials. This article highlights those trials, and describes the current pharmacological management of the... Continue Reading →

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