Tag: theragnostic

Skin autofluorescence for non-enzymatic glycation end products in Diabetic Foot Ulcers (DFUs)- A meta analysis

Continued efforts to create companion diagnostics and theragnostics to help us measure what we manage and predict DFU risk. Imagine diagnosing "friable" tissue and then doing something about it?! Objective: Skin autofluorescence (SAF) has been suggested as a novel and noninvasive technique for assessing tissue accumulation of advanced glycation end products in diabetes and related complications.... Continue Reading →

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The Rebirth of Matrix Metalloproteinase (MMP) Inhibitors?

Compelling work from Fields at Scripps, Florida suggest that we may be entering a new era of selective MMP inhibitors that may have profound implications from wound healing to cancer therapy. Buckle up!

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Study: People with Diabetic Foot Ulcers Don’t Vasodilate after Pressure Challenge. A New Marker for Risk (and Treatment Target)?

Important new work from our Lyonnaise and German colleagues published in the journal Diabetes. Neurovascular response to pressure in patients with diabetic foot ulcer Julien Vouillarmet MD1, Audrey Josset-Lamaugarny2,3, Paul Michon MD1, Jean Louis Saumet MD, PhD2,3, Audrey Koitka-Weber PhD4,5, Samir Henni MD4, Berengere Fromy PhD2,3, Dominique Sigaudo-Roussel PhD2,3 Diabetic foot ulcer (DFU) is a... Continue Reading →

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High-Resolution Spectral Analysis Accurately Identifies the Bacterial Signature in Infected Chronic Foot Ulcers in People With Diabetes

Will we soon see more visual diagnostics for wounds? Congratulations to our colleagues in Melbourne for these intriguing data. Diabetic foot infections are a major cause of hospitalization, and delayed treatment can lead to numerous complications. The aim of this research was to investigate high-resolution spectroscopy of the wound center and periwound area for real-time... Continue Reading →

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