Our new paper in Burns and Trauma presents the most comprehensive review yet of spooky action at a distance therapies for diabetic limb preservation — from spinal cord stimulation and splenic ultrasound to remote ischemic conditioning and tibial transport. Five modalities, three mechanistic pathways, one shared destination: tissue repair at a distance.
A 3D Panoramic View Into the Body: Introducing RUS-PAT Imaging #ActAgainstAmputation @Caltech @USC_Vascular @NeurosurgeryUSC @KeckSchool_USC @USC @NatBME
Our colleagues at Caltech and USC Vascular Surgery and Neurosurgery, including Lihong Wang, Charles Liu, Tze Woei Tan, and Jonathan Russin, have unveiled a major leap in medical imaging. Published in Nature Biomedical Engineering, the team introduces Hybrid Rotational Ultrasound and Photoacoustic Tomography (RUS-PAT). Think of it as a high-speed, 3D panoramic camera for our... Continue Reading →
Unlocking the Potential of Pedal Acceleration Time in Peripheral Artery Disease Diagnosis: The Latest Data #ActAgainstAmputation #Diagnostics #CLTI
Peripheral artery disease (PAD) is a widespread but often underdiagnosed condition affecting millions worldwide. Traditional diagnostic tools like the ankle-brachial index (ABI) and toe-brachial index (TBI) have limitations, particularly in patients with diabetes or medial arterial calcification. A newly published study in the European Journal of Vascular & Endovascular Surgery by Sommerset et al. introduces pedal acceleration time... Continue Reading →
Accuracy of the pedal acceleration time to diagnose limb ischemia in patients with and without diabetes using the WIfI classification #ActAgainstAmputation @ALPSlimb
Accuracy of the pedal acceleration time to diagnose limb ischemia in patients with and without diabetes using the WIfI classification Excellent work from Castro-Santos and coworkers. Accuracy of the pedal acceleration time to diagnose limb ischemia in patients with and without diabetes using the WIfI classification Introduction: Evaluation of limb hemodynamics using the ankle–brachial index... Continue Reading →
Potential Utility of Ultrasound-Enhanced Delivery of Antibiotics, Anti-Inflammatory Agents, and Nutraceuticals @USC @USC_Vascular #ActAgainstAmputation @ALPSLimb
Potential Utility of Ultrasound-Enhanced Delivery of Antibiotics, Anti-Inflammatory Agents, and Nutraceuticals: A Mini Review This from our USC SALSA Team led by Karim Ead and Arjun Sharma. Abstract: Ultrasound technology has therapeutic properties that can be harnessed to enhance topical drug delivery in a process known as phonophoresis. The literature on this method of drug... Continue Reading →
Ultrasound-Assisted Wound (UAW) Debridement in the Treatment of Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis @JosLuisLzaroMa1 #Diabeticfoot @alpslimb 
More and more data to support improvement in wound optimization with ultrasound assisted wound debridement from our long-time friends from the Complutense in Madrid. A systematic review and meta-analysis were carried out to investigate the effect of ultrasound-assisted wound (UAW) debridement in patients with diabetic foot ulcers (DFUs). All selected studies were evaluated using the... Continue Reading →
An in vivo model for overloading-induced soft tissue injury #ActAgainstAmputation #DiabeticFoot #Theragnostics #Diagnostics @ALPSlimb @Staffsbiomech
Strong work from our Staffordshire colleagues Chatzistergos and Chockalingam who continue to help push the envelope in helping us collectively measure what we manage. An in vivo model for overloading-induced soft tissue injury This proof of concept study demonstrates that repetitive loading to the pain threshold can safely recreate overloading induced soft tissue damage and... Continue Reading →
@USC Limb Preservation Program gets $1.43 million Dept. of Defense grant @KeckMedUSC
VIA Keck School News The USC Limb Preservation Program has been awarded an 18-month, $1.43 million grant from the Department of Defense to support an innovative wound-healing program. The group will be studying the effects of stimulating the spleen in people with catastrophic tissue loss to promote the release of anti-inflammatory cells and cytokines. The... Continue Reading →