On diabetic foot, wound healing, amputation prevention, and the merger of consumer tech with medical devices
Congratulations to our friend and Schaeffer CenterUniversity of Southern California research partner Ritika Chaturvedi on this monumental effort. American Life in Realtime (ALiR) FTW! See the compelling article about this program here.
Compelling work from Elsherif and coworkers Abstract Diabetes mellitus is a chronic disease requiring a careful management to prevent its collateral complications, such as cardiovascular and Alzheimer's diseases, retinopathy, nephropathy, foot and hearing impairment, and neuropathy. Self-monitoring of blood glucose at point-of-care settings is an established practice for diabetic patients. However, current technologies for glucose... Continue Reading →
Great work from our colleagues at IKEM and Manchester. Bottom line: Pay attention to CRP, polymorphisms to methylenetetrahydrofolate reductase (MTHFR) as well as low TCPO2 Key points: The aim of our study was to assess the risk factors for major amputation in patients with CLTI and DFU during a 2-year follow-up after ACT.One hundred and... Continue Reading →
This from Rong and coworkers Summary Points: Diabetic foot ulcer (DFU) is a complex and devastating complication of diabetes mellitus that are usually stagnant in the inflammatory phase.However, oral wound healing, which is characterized by a rapid and scarless healing process, is regarded an ideal model of wound healing.Thus, we performed a comprehensive bioinformatics analysis... Continue Reading →
A superb manuscript from Meghan Brennan and coworkers from Wisconsin. This so clearly shows the overlap of socioeconomic status, rurality, and ethnicity. Key Points Question Is the intersection of race, ethnicity, rurality, and/or neighborhood disadvantage associated with outcomes among US patients with diabetic foot ulcers? Findings In this cohort study of 124 487 patients hospitalized with diabetic foot... Continue Reading →
More work supporting the ongoing efforts to create a deep learning/AI model to assist in diagnosis of diabetic foot ulcer/wound healing images J Yogapriya 1, Venkatesan Chandran 2, M G Sumithra 3, B Elakkiya 4, A Shamila Ebenezer 5, C Suresh Gnana Dhas 6 A bacterial or bone infection in the feet causes diabetic foot infection (DFI), which results in reddish skin in the wound and... Continue Reading →
Important work from our colleagues throughout the Gulf states. Anchored by Rayaz Malik of Cornell/Doha. Bottom line- the largest ever study in the region shows that so much of this is silent and sinister. For instance: 43% prevalence of painful diabetic neuropathy of whom 54% were undiagnosed. Risk factors for painless, painful neuropathy and diabetic... Continue Reading →
Gassel and coworkers report DOWNREGULATION of WNT signaling in Charcot Arthropathy published in BMC Musculoskeletal Disorders Background Type 2 diabetes mellitus (T2DM) patients show a markedly higher fracture risk and impaired fracture healing when compared to non-diabetic patients. However in contrast to type 1 diabetes mellitus, bone mineral density in T2DM is known to be... Continue Reading →
This from our colleagues at Charing Cross Hospital. Offloading treatment in people with diabetic foot disease: A systematic scoping review on adherence to foot offloading Highlights A review of adherence to offloading treatment for people with diabetes and foot disease.• Adherence to offloading treatment is influenced by biological and psychosocial factors.• Abnormal gait and postural... Continue Reading →
More and more data to support improvement in wound optimization with ultrasound assisted wound debridement from our long-time friends from the Complutense in Madrid. A systematic review and meta-analysis were carried out to investigate the effect of ultrasound-assisted wound (UAW) debridement in patients with diabetic foot ulcers (DFUs). All selected studies were evaluated using the... Continue Reading →
