Armstrong Keynotes International Foot and Ankle Biomechanics (#iFAB2021) symposium from Rancho Los Amigos @RanchoRehab RanchoResearchI @KeckMedUSC @USC_Vascular @USC

David G. Armstrong, Professor of Surgery at the Keck School of Medicine of University of Southern California joined physicians, surgeons, engineers and scientists from around the world for the International Foot and Ankle Biomechanics conference. Originally scheduled for Rio De Janiero, Brazil in April of 2020 and chaired by Prof. Isabelle Sacco, the symposium- known […]

Read More Armstrong Keynotes International Foot and Ankle Biomechanics (#iFAB2021) symposium from Rancho Los Amigos @RanchoRehab RanchoResearchI @KeckMedUSC @USC_Vascular @USC

Long-term followup of conservative management of Charcot feet – 93% amputation-free survival at 5 years

Excellent work from our friends and colleagues at the Balgrist in Zurich. Abstract Background: Charcot arthropathy (CN) can ultimately lead to limb loss despite appropriate treatment. Initial conservative treatment is the accepted treatment in case of a plantigrade foot. The aim of this retrospective study was to investigate the mid- to long-term clinical course of CN […]

Read More Long-term followup of conservative management of Charcot feet – 93% amputation-free survival at 5 years

Effect of High-frequency Spinal Cord Stimulation in Patients With Painful Diabetic #Neuropathy: A Randomized Clinical Trial @JAMANeuro

Intriguing report from Petersen and coworkers for a common, complex and costly condition. Importance  Many patients with diabetic peripheral neuropathy experience chronic pain and inadequate relief despite best available medical treatments. Objective  To determine whether 10-kHz spinal cord stimulation (SCS) improves outcomes for patients with refractory painful diabetic neuropathy (PDN). Design, Setting, and Participants  The prospective, multicenter, open-label […]

Read More Effect of High-frequency Spinal Cord Stimulation in Patients With Painful Diabetic #Neuropathy: A Randomized Clinical Trial @JAMANeuro

Scientists connect human brain to computer wirelessly for first time ever

Via the Independent: The first wireless commands to a computer have been demonstrated in a breakthrough for people with paralysis. The system is able to transmit brain signals at “single-neuron resolution and in full broadband fidelity”, say researchers at Brown University in the US. A clinical trial of the BrainGate technology involved a small transmitter […]

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Reading Minds With Ultrasound: Caltech’s New Brain–Machine Interface

Via SciTech Daily What is happening in your brain as you are scrolling through this page? In other words, which areas of your brain are active, which neurons are talking to which others, and what signals are they sending to your muscles? Mapping neural activity to corresponding behaviors is a major goal for neuroscientists developing […]

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Efficacy of topical vancomycin and gentamicin loaded calcium sulfate beads or systemic antibiotics in eradicating polymicrobial biofilms isolated from diabetic foot infections

Crowther and coworkers publish this work in Antimicrobial Agents and Chemotherapy lending further strength to the goal of maximizing antimicrobial therapy at the site of infection. Diabetic foot ulcers are notoriously difficult to heal, with ulcers often becoming chronic, in many cases leading to amputation despite weeks or months of antibiotic therapy in addition to […]

Read More Efficacy of topical vancomycin and gentamicin loaded calcium sulfate beads or systemic antibiotics in eradicating polymicrobial biofilms isolated from diabetic foot infections

6.3 fold greater risk for mortality in people presenting with heel ulcers vs. forefoot ulcers

Intriguing work from Schofield and coworkers from the Salford Royal Infirmary report an independent risk of hindfoot DFU vs forefoot in the journal Diabetic Medicine. Introduction: We previously demonstrated in both a longitudinal study and in meta-analysis (pooled relative-risk RR, 2.45) that all-cause mortality is significantly higher in people with diabetes foot ulceration (DFU) than with […]

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A Meta-Analysis of the Outcomes of Resection Arthroplasty for Resistant Hallucal Diabetic Ulcers – PubMed

Great work from Yammine and Assi summarizing the state of play for this useful and still likely underutilized procedure for hallux ulcers. The standard medical care (SC) of non-infected diabetic foot ulcers (DFUs) has been reported to yield varying rates of wound healing with high recurrence rate in non-infected wounds. Conservative surgery has been advanced […]

Read More A Meta-Analysis of the Outcomes of Resection Arthroplasty for Resistant Hallucal Diabetic Ulcers – PubMed