Author: David G. Armstrong

Dedicated to amputation prevention, wound healing, diabetic foot, biotechnology and the intersection between medical devices and consumer electronics.

Incidence, hospitalization and mortality and their changes over time in people with a first ever diabetic foot ulcer

Important work from the UK’s Primary Care Database suggests that the incidence of diabetic foot ulcers, hospitalizations and mortality appears to have reduced over the past decade in people with type 2 diabetes. Aims: A diabetic foot ulcer (DFU) is a severe condition associated with morbidity and mortality. Population-based studies are rare and limited by […]

Read More Incidence, hospitalization and mortality and their changes over time in people with a first ever diabetic foot ulcer

An intelligent insole system with personalised digital feedback reduces foot pressures during daily life: an 18-month randomised controlled trial

Excellent work from our Mancunian colleagues. Highlights •An insole system continuously monitors daily plantar pressure for 18 months. •Personalised pressure feedback reduces foot pressure in feet at high-risk of ulcers. •Pressure feedback induced a learning response. Abstract Aims High plantar pressure is a major risk factor in the development of diabetic foot ulcers (DFUs) and […]

Read More An intelligent insole system with personalised digital feedback reduces foot pressures during daily life: an 18-month randomised controlled trial

Since sitting is the new smoking, should we be squatting more?

Great work from our long-time SALSAmigo, Dave Raichlen summarized in this NYT article by Gretchen Reynolds If you are sitting down to read this article, you may be doing your resting wrong, according to a fascinating new study of hunter-gatherer tribespeople and how they idle. The study finds that hunter-gatherers tend to lounge about during the day […]

Read More Since sitting is the new smoking, should we be squatting more?

@USC David G. Armstrong becomes first Podiatric Surgeon to Deliver Surgery Grand Rounds to George Washington University

David G. Armstrong, Professor of Surgery and Director of the Limb Preservation Program at Keck School of Medicine of University of Southern California (USC) became the first podiatric surgeon to deliver surgery grand rounds at George Washington University in Washington DC. His lecture, which focused on building limb preservation programs, worldwide, was moderated by Anton […]

Read More @USC David G. Armstrong becomes first Podiatric Surgeon to Deliver Surgery Grand Rounds to George Washington University

New Insights on the Effects of Dietary Omega‐3 Fatty Acids on Impaired Skin Healing in DFU and VLU #DiabeticFoot #Wound Healing

A terrific review by Rome’s Serini and Calviello Long-chain Omega-3 polyunsaturated fatty acids (Omega-3 PUFAs) are widely recognized as powerful negative regulators of acute inflammation. However, the precise role exerted by these dietary compounds during the healing process is still largely unknown, and there is increasing interest in understanding their specific effects on the implicated […]

Read More New Insights on the Effects of Dietary Omega‐3 Fatty Acids on Impaired Skin Healing in DFU and VLU #DiabeticFoot #Wound Healing

A Clinical Study to Evaluate Autofluorescence Imaging of Diabetic Foot Ulcers Using a Novel Artificial Intelligence Enabled Noninvasive Device #ActAgainstAmputation #DiabeticFoot

A Clinical Study to Evaluate Autofluorescence Imaging of Diabetic Foot Ulcers Using a Novel Artificial Intelligence Enabled Noninvasive Device Great work from our long-time friend and colleague Vijay Viswanathan and coworkers pushing diagnostics and theragnostics forward. Diabetic foot ulcers, with worldwide prevalence ranging from 12%-25%, are an important cause of nontraumatic lower limb amputation. Evidence-based […]

Read More A Clinical Study to Evaluate Autofluorescence Imaging of Diabetic Foot Ulcers Using a Novel Artificial Intelligence Enabled Noninvasive Device #ActAgainstAmputation #DiabeticFoot

The association of chronic, enhanced immunosuppression (especially dialysis) with outcomes of diabetic foot infections

Yet more information on the role that immunosuppression (including and especially renal replacement) plays on outcomes of diabetic foot infections. This from our friends and colleagues from the Balgrist in Zurich. Ilker Uçkay 1 2 3, Madlaina Schöni 2, Martin C Berli 2, Fabian Niggli 2 3, Emil Noschajew 2, Benjamin A Lipsky 4, Felix W A Waibel 2 We investigated if a chronic, enhanced immunosuppressed condition, beyond the immunodeficiency related […]

Read More The association of chronic, enhanced immunosuppression (especially dialysis) with outcomes of diabetic foot infections

Proteomics changes after negative pressure wound therapy in diabetic foot ulcers

Excellent continued efforts in elucidating the role that perturbation of the wound matrix (via NPWT) has on angiogenesis, healing and regeneration. Label‑free quantitative mass spectrometry was used to analyze the differences in the granulation tissue protein expression profiles of patients with diabetic foot ulcers (DFUs) before and after negative‑pressure wound therapy (NPWT) to understand how […]

Read More Proteomics changes after negative pressure wound therapy in diabetic foot ulcers

From our combined team: Time in Range (TIR) may help to predict amputation and mortality risk #ActAgainstAmputation @USC @USC_Vascular @KeckSchool_USC

This from our combined Chongqing/Singapore/USC team. This adds additional data pointing to a relationship with glucose, morbidity and mortality in high risk diabetic foot patients. Aims: To evaluate the association of time in range (TIR) with amputation and all-cause mortality in hospitalized patients with diabetic foot ulcers (DFUs) MATERIALS AND METHODS: A retrospective analysis was performed […]

Read More From our combined team: Time in Range (TIR) may help to predict amputation and mortality risk #ActAgainstAmputation @USC @USC_Vascular @KeckSchool_USC

@USC Armstrong Becomes First Podiatric Surgeon to Keynote Diabetic Foot Grand Challenge at International Computing Imaging Conference in Strasbourg @keckmedusc @usc_vascular @Keckschool_usc #ActAgainstAmputation @alpslimb

USC Professor of Surgery David G. Armstrong became the first podiatric surgeon to keynote a session at the 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI). Armstrong’s lecture described the toll that diabetes complications take worldwide as well as the role that advances in artificial intelligence, advanced imaging and robotics can […]

Read More @USC Armstrong Becomes First Podiatric Surgeon to Keynote Diabetic Foot Grand Challenge at International Computing Imaging Conference in Strasbourg @keckmedusc @usc_vascular @Keckschool_usc #ActAgainstAmputation @alpslimb