Author: David G. Armstrong

Dedicated to amputation prevention, wound healing, diabetic foot, biotechnology and the intersection between medical devices and consumer electronics.

Three Nutritional Indices Are Effective Predictors of Mortality in Patients With Type 2 Diabetes and Foot Ulcers #Nutrition @ALPSLimb #ActAgainstAmputation

Hong and coworkers with some pragmatic predictive work Introduction Malnutrition has been associated with mortality in various diseases. This retrospective cohort study aimed to investigate the relationship between three nutritional indices and all-cause mortality in patients with diabetic foot ulcers (DFUs). Materials and Methods A total of 771 patients diagnosed with DFUs in the First... Continue Reading →

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Metagenomics of Diabetic Foot Ulcer Undergoing Treatment with Total Contact Casting (TCC) @USC_vascular @USC @ALPSlimb @CosmosID

This initial look into what may be a routine survey of metagenomic data from week to week. Led by FASMA's Adam Isaac, CosmosID's (National Science Foundation Director Emerita) Prof. Rita Colwell and our team. Objective: Diabetic foot ulcers (DFUs) are characterised by the presence of many microbes, some of which may not be identified by traditional... Continue Reading →

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@VascularSVS Webinar Highlights WIfI, Global Vascular Guidelines to help #ActAgainstAmputation @ALPSlimb @jmills1955 @USCFVascular @UWSurgery @USC_Vascular @USC @VascularCures @APMA

Profs. DG Armstrong (USC) Noboyushi Azuma (Asahikawa University), Sanjay Misra (Mayo) and Elina Quiroga (University of Washington) joined chairs Profs. Michael Conte (UCSF), John White (Advocate) and Joseph Mills (Baylor College of Medicine) to review implementation of Global Vascular Guidelines in limb preservation. David G. Armstrong, Professor of Surgery and Director of the Southwestern Academic... Continue Reading →

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@USC Professor Armstrong Keynotes Polish Wound Healing Symposium, Features Diabetic Limb Preservation with Focus on Ukraine @ALPSlimb @KeckSchool_USC @USC_Vascular

David G. Armstrong, Professor of Surgery and Director of the Southwestern Academic Limb Salvage Alliance at USC, joined more than 500 colleagues in Gdansk, Poland for the 20th Jubilee of the Polish Scientific Congress on Wound Healing. His lecture focused on the state of play for efforts in limb preservation, worldwide. This was followed by... Continue Reading →

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Outpatient clinic attendance and outcomes among patients hospitalized with diabetic foot ulcers

Important, revealing work from Emory's diabetic foot team featuring Marcos Schechter from a county hospital system. Background: There are limited data on post-hospital discharge clinic attendance rates and outcomes among patients with diabetic foot ulcers (DFUs). Methods: Retrospective study of patients hospitalized with a DFU from 2016 to 2019 in a large public hospital. We measured rates... Continue Reading →

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Delayed Diagnosis of Charcot Foot: A Systematic Review

From Daniel Jupiter's team in Galveston, led by Korst. This study aims to examine the duration and rate of delayed diagnosis in Charcot foot. We systematically reviewed articles published in Medline, SCOPUS, and Cumulative Index of Nursing and Allied Health Literature to identify articles discussing delayed or misdiagnosis of Charcot foot. Random-effects models were generated... Continue Reading →

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Racial Disparities in Health Care With Timing to Amputation Following Diabetic Foot Ulcer @ALPSlimb #ActAgainstAmputation

Important work from Miller and coworkers in Diabetes Care. Objective: To examine variations in timing of lower-limb amputation (LLA) across race/ethnicity and sex among older adults with a diabetic foot ulcer (DFU). It was hypothesized Black/African Americans were more likely to have LLA post-DFU earlier compared with non-Hispanic/Whites, and more men would receive LLA earlier post-DFU... Continue Reading →

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Translational development of ABCB5 + dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers @alpslimb

Promising work from Heisler, Orgill and team. Background: While rapid healing of diabetic foot ulcers (DFUs) is highly desirable to avoid infections, amputations and life-threatening complications, DFUs often respond poorly to standard treatment. GMP-manufactured skin-derived ABCB5+ mesenchymal stem cells (MSCs) might provide a new adjunctive DFU treatment, based on their remarkable skin wound homing and engraftment potential,... Continue Reading →

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Evaluation of quality of diabetic foot examination on @YouTube #ActAgainstAmputation @ALPSlimb

Fascinating work by Almaqhawi and coworkers that may have immediate applicability in weeding out good quality from less good educational materials online. Introduction: Foot ulcers and amputations are common conditions in people with diabetes and can considerably impact quality of life, necessitate a lengthy hospital stay and increase mortality. Preventative foot care and examination can prevent... Continue Reading →

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Individualised risk prediction for improved chronic wound management @USC_Vascular @ResearchatUSC @ALPSlimb #AI #DeepLearning #WoundHealing

This manuscript from our combined team led by Vladica Velickovic exploring deep learning models to improve our diagnostic and therapeutic methods to measure what we manage. Significance Chronic wounds are associated with significant morbidity, marked loss of quality of life and considerable economic burden. Evidence-based risk prediction to guide improved wound prevention and treatment is... Continue Reading →

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