@USC Names David G. Armstrong a Distinguished Professor

LOS ANGELES — The University of Southern California has named Dr. David G. Armstrong, a global leader in diabetic limb preservation and surgery, a Distinguished Professor in recognition of his pioneering contributions to research, clinical care, and interdisciplinary innovation. Dr. Armstrong, Professor of Surgery and Neurological Surgery at USC, has authored more than 710 peer-reviewed papers and leads the university’s NSF-funded Center... Continue Reading →

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Imagine: A Smart Reactive Hydrogel To Revolutionize Diabetic Wound Healing #MMP9 #Inflammation #CompanionDiagnostic #ActAgainstAmputation

Diabetic wounds present one of the most complex and persistent challenges in modern medicine, often leading to prolonged inflammation and impaired healing. A recent study by Meng et al. (2025) introduces a potentially groundbreaking solution: a smart, MMP-9-responsive hydrogel that releases M2 macrophage-derived exosomes (M2-Exos) in response to the inflammatory microenvironment of diabetic wounds. This innovation has the potential... Continue Reading →

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Not All in Vein: Oral Antibiotics for Diabetic Foot Osteomyelitis #ActAgainstAmputation @USC_Vascular @researchatusc @KeckSchool_USC @LimbsandLungs

A growing body of evidence suggests that oral antibiotics may be as effective as intravenous (IV) therapy for treating diabetic foot osteomyelitis (DFO)—a severe and limb-threatening infection commonly associated with diabetic foot ulcers. Traditionally, IV antibiotics have been the gold standard, but a newly published narrative review from our combined team in the Journal of... Continue Reading →

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Physicians Are Healing Themselves—A Reflection on @GinaKolata NYT Article and Our Colleague, Prof. John Buse

Screenshot In a recent New York Times article, Gina Kolata explores a striking trend in modern medicine: physicians, particularly in cardiology and endocrinology, are increasingly turning to GLP-1 receptor agonists like Ozempic, Wegovy, and Zepbound—not just for their patients, but for themselves. The piece highlights how these medications, initially designed to manage diabetes, are now being embraced by medical professionals... Continue Reading →

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Knock your sox off and #ActAgainstAmputation @ALPSlimb #DiabeticFoot

https://www.youtube.com/shorts/RQXWWCxApL8

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Time is Tissue! #ActAgainstAmputation #YouTube #DiabeticFoot

https://www.youtube.com/shorts/agTo8u9jS3U

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Bridging the Gap From Healing to Remission: Best Practices for Offloading in Diabetic Foot Care– Data from Lazzarini and Van Netten #ActAgainstAmputation @ALPSlimb #Remission

Diabetes-related foot disease (DFD) affects an estimated 200 million people globally, surpassing the disease burden of conditions like stroke and breast cancer. In their comprehensive article, Best Practice Offloading Treatments for Diabetic Foot Ulcer Healing, Remission, and Better Plans for the Healing-Remission Transition (Seminars in Vascular Surgery, 2025), Dr. Peter Lazzarini and Dr. Jaap J. van Netten examine the current state... Continue Reading →

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WIfI in under 60 seconds- Wound, Ischemia, Foot infection and limb threat #ActAgainstAmputation

https://www.youtube.com/watch?v=zeXVMxy6k30 Thanks to Magdalena Antoszewska for her wizardry in putting together this video. Here's to working to #ActAgainstAmputation For more on this blog (there's quite a lot) see below for a sample. 3 rings of risk WIFI plus Function Evolution of WIfI: Expansion of WIfI Notation After Intervention #ActAgainstAmputation @alpslimb @vascularsvs @USC_vascular @UCSFVascular @jmills1955 @VirginiePhD_POD... Continue Reading →

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The Power of Movement: The Role of Physical Activity in Enhancing Perfusion #ActAgainstAmputation #Movement #Activity

In an important systematic review and meta-analysis published in the Journal of Tissue Viability , our colleagues Palacios-Abril et al. (2025) explore the impact of physical activity on tissue perfusion in patients with diabetes mellitus (DM). Their findings provide compelling evidence that exercise can significantly enhance microvascular function in the lower limbs, a critical factor... Continue Reading →

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The Future of Mobility: Brain-Controlled Bionic Legs

Imagine a future where prosthetics are seamlessly controlled by the brain, restoring not only mobility but also a sense of wholeness to individuals who have lost limbs. A recent New Yorker article, “A Bionic Leg Controlled by the Brain” (read it here), introduces the revolutionary work of Hugh Herr, a visionary inventor and scientist, whose personal journey and cutting-edge... Continue Reading →

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