Silent and sinister: High Prevalence of Silent, Severe Coronary Ischemia in Patients with Diabetic Foot Ulcers: New Research Insights @farkomd @jvascsurg @alpslimb

A new manuscript published in the Journal of Vascular Surgery sheds light on the alarming prevalence of silent, severe coronary ischemia in patients with diabetic foot ulcers (DFU). The study, “High Prevalence of Silent, Severe Coronary Ischemia in Patients with Diabetic Foot Ulcers,” demonstrates that a significant proportion of DFU patients—without overt history of coronary artery... Continue Reading →

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Machine Learning to Diagnose Complications of #Diabetes #AI/ML

A new manuscript in the Journal of Diabetes Science and Technology from our global team explores how machine learning is being used to detect, diagnose, and even predict complications of diabetes. The paper, authored by Agatha Scheideman, Mandy Shao, Henry Zelada, Jorge Cuadros, Joshua Foreman, Pinaki Sarder, Cindy Ho, Niels Ejskjaer, Jesper Fleischer, Simon Lebech... Continue Reading →

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When Noncommunicable Diseases Overtook the World: Where We Stand Today and a Peek into the Future #NCDs #Lancet

Probability of dying from a non communicable disease: Change between 2010 and 2020, worldwide For much of human history, infectious diseases, maternal and neonatal conditions, and nutritional deficiencies defined the leading edge of mortality. Plagues, diarrheal disease, and tuberculosis were the archetypal killers. By contrast, noncommunicable diseases (NCDs)—heart disease, cancer, diabetes, chronic lung disease—were rare,... Continue Reading →

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Message from Singapore: Team up to #ActAgainstAmputation at ASVS and DFCon Asia @ALPSlimb #DiabeticFoot

This note from Singapore and ALPS. Singapore, September 2025 The American Limb Preservation Society (ALPS) and Diabetic Foot Conference (DFCon) proudly announce their successful participation in the ASVS 2025 Annual Meeting, held this year in Singapore. Their involvement brought a unique and multidisciplinary perspective to the meeting, further reinforcing the importance of collaboration in advancing... Continue Reading →

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Balancing Costs, Access, and Innovation in Wound Healing: A Logical Approach? #CAMPs #ActAgainstAmputation

Recent reforms proposed by the Centers for Medicare & Medicaid Services (CMS) were designed to tackle waste and soaring costs in advanced wound care—specifically around skin substitutes, also known as cellular, acellular, and matrix-like products (CAMPs). While the intent is to curb fraud and level the playing field, the reality is much more complex. Our... Continue Reading →

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A Global Consensus on Diabetic Wound Management #ActAgainstAmputation

This open-access consensus (Advances in Wound Care, 2025) synthesizes practical, evidence-driven guidance for the bedside management of diabetic wounds—spanning pathophysiology, glycemic care, infection/biofilm control, vascular assessment and revascularization, offloading, surgery, pain, dressings, and emerging therapies. Contributors (acknowledged individually)• Henry C. Hsia• Elof Eriksson• Geoffrey C. Gurtner• Aristidis Veves• Osama Hamdy• David J. Margolis• David G.... Continue Reading →

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Compromised Skin Barrier at Wound Closure Predicts Recurrence of Diabetic Foot Ulcers: A New TEWL? #ActAgainstAmputation @NIDDKGov #DFC @DiabetesCareADA @ALPSLimb

I An important multicenter study from our colleagues Sen and coworkers and the NIH’s Diabetic Foot Consortium, conducted through the NIDDK Diabetic Foot Consortium, has provided strong evidence that functional closure—not just structural closure—matters when it comes to diabetic foot ulcers (DFUs). Published in Diabetes Care, this prospective noninterventional study followed 418 patients with recently... Continue Reading →

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Saving Limbs in Diabetes While Fighting Cancer: A New Approach at City of Hope @CityofHope @JAPMAFeetTweets @ALPSlimb

For patients battling both diabetes and cancer, even a small foot wound can carry devastating consequences. Chemotherapy, radiation, immunotherapy, and stem cell transplants all compromise immunity and circulation. Add diabetes to the mix, and the risk of diabetic foot ulcers (DFUs) and amputations rises dramatically. What’s more, even minor foot infections can force oncologists to... Continue Reading →

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Inflammation, Lipids, and Limb Risk: New Clues from Two Cohorts #ActAgainstAmputation #PAD #VascularDisease #CLTI

Peripheral artery disease (PAD) is one of the most devastating complications of diabetes—contributing to ischemic pain, functional decline, and, in severe cases, amputation. Despite its prevalence, early detection remains elusive, and clinicians continue to search for simple, reliable markers of risk. A new multicohort study led by Wang and colleagues now shines a spotlight on... Continue Reading →

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Boosting Healing: Could Vitamin D be a Significant, Inexpensive, Widely-available Adjunct in Treating Diabetic Foot Ulcers #ActAgainstAmputation #DFU #Nutrition

For millions living with diabetes, foot ulcers are more than a painful inconvenience—they’re a serious, often underestimated health threat. With sluggish healing and high infection risks, DFUs dramatically increase the likelihood of hospitalization and amputation. But a recent clinical trial points to a simple, well-known compound—vitamin D—as a powerful ally in the battle against DFUs.... Continue Reading →

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