Boosting Healing: Could Vitamin D be a Significant, Inexpensive, Widely-available Adjunct in Treating Diabetic Foot Ulcers #ActAgainstAmputation #DFU #Nutrition

For millions living with diabetes, foot ulcers are more than a painful inconvenience—they’re a serious, often underestimated health threat. With sluggish healing and high infection risks, DFUs dramatically increase the likelihood of hospitalization and amputation. But a recent clinical trial points to a simple, well-known compound—vitamin D—as a powerful ally in the battle against DFUs.... Continue Reading →

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🧠 The Phantom Persists: Brain Maps Stay Intact After Amputation

Contrary to long-standing assumptions about massive cortical reorganization following limb loss, this longitudinal study reveals that the brain’s somatosensory map is far more stable than previously believed. 🔍 Study Design: A Rare Longitudinal Window While past research on cortical reorganization often relied on cross-sectional comparisons between amputees and controls, this study by Schone et al. took a... Continue Reading →

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Frailty Progression and Outcomes in Patients with Diabetic Foot Ulcers: New Insights from @USC @keckschool_usc @USC_Vascular #ActAgainstAmputation

We are pleased to share our team’s latest publication led by super sudents Alex Hong, Ivan Luu and Brandan Deras-Guerra under the direction of Tze Woei Tan in the journal Surgery: Hong AT, Luu IY, Deras-Guerra B, Han S, Shin L, Shih C-D, Armstrong DG, Tan T-W. “Association between frailty progression and clinical outcomes in patients... Continue Reading →

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Mapping Two Decades of Progress: Global Trends in Diabetic Foot Research #ActAgainstAmputation #DiabeticFoot

A new bibliometric study published in the International Journal of Environmental Research and Public Health offers the most comprehensive look yet at the evolution of diabetic foot research over the past 20 years . By analyzing more than 7,100 publications indexed in Scopus between 2004 and 2023, the authors reveal how scientific production has expanded, who is leading the... Continue Reading →

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When Science Becomes Family: A Conversation on DFU, CLTI, and Recurrence Risk

It’s not every day that the professional and the personal intersect in such a deeply life-affirming way. Our latest publication in the International Wound Journal, “Three-Year Recurrence in People With Diabetic Foot Ulcers and Chronic Limb Threatening Ischemia Is Comparable to Cancer,” brought together an extraordinary team of colleagues from UCSF, Baylor College of Medicine, USC,... Continue Reading →

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Galectin-3 and Diabetic Wound Healing: Turning On the Growth Switch While Releasing the Brakes #ActAgainstAmputation #DiabeticFoot

A new study in Nature Communications uncovers how a sugar-binding protein, Galectin-3, can be harnessed to speed healing in diabetic foot ulcers — and how to bypass a major biochemical roadblock.** Diabetic foot ulcers (DFUs) remain one of the most stubborn complications of diabetes — affecting up to 30% of patients, with recurrence rates approaching 65% within 3–5 years and... Continue Reading →

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Championing Limb Preservation in Rural Appalachia #ActAgainstAmputation @DukeVascular @WVUvascular @ALPSlimb @JVascSurg #DiabeticFoot

A New Insight from Samantha D. Minc, MD, MPH, and Team Samantha D. Minc, MD, MPH—now at Duke University—and her coworkers have reported a compelling data in the Journal of Vascular Surgery, titled “Identifying the challenges of amputation prevention in a rural state with mixed methods research engaging patients and providers.” This study employs both quantitative and qualitative... Continue Reading →

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📈 Mapping the Footprint of Progress: A Decade of Diabetic Foot Ulcer Research #ActAgainstAmputation @alpslimb @keckschool_usc @usc_vascular

📈 Mapping the Footprint of Progress: A Decade of Diabetic Foot Ulcer Research Over the past ten years, diabetic foot ulcer (DFU) research has undergone a remarkable transformation, expanding in scale, sophistication, and global participation. A newly published bibliometric study offers a sweeping view of this evolution—highlighting emerging trends, global contributors, and the scholars shaping... Continue Reading →

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Reshaping the Sausage Toe: Revisiting Internal Pedal Amputation for Chronic Osteomyelitis in the diabetic foot #ActAgainstAmputation

A newly published case series by our colleagues Yammine and colleagues in the International Wound Journal sheds light on a deceptively humble yet visually distinctive presentation in the diabetic foot: the “sausage toe.” Once thought rare, this bulbous, swollen toe is increasingly recognized as a clinical marker of underlying osteomyelitis. The study offers a thoughtful reappraisal of... Continue Reading →

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🔬 A Smart Boot + Digital Monitoring = Game-Changer in Diabetic Foot Ulcer Care! #ActAgainstAmputation @phrmafoundation @uscshaeffer @USC @NIDDKgov #C2SHiP @KeckSchool_USC

I’m thrilled to see Emily Ortman’s PhRMA Foundation blog spotlight our team’s work at USC—funded by a $500K PhRMA Foundation grant—on a smart offloading boot paired with a smartwatch-based digital monitoring platform to improve wound healing for diabetic foot ulcers (DFUs). ➡️ Why this matters: The smart boot reduces pressure on foot wounds while embedded sensors capture real-time... Continue Reading →

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