Do Anti-Biofilm Antibiotics Have A Place in the Treatment of Diabetic Foot Osteomyelitis? @ALPSlimb #ActAgainstAmputation

Here is a copy of a preprint from our long-time friend and colleague Eric Senneville and coworkers. The choice of antibiotic regimens to use in patients presenting with diabetic foot osteomyelitis and their duration differs according to the situation. Antibiotics play a more important role in the medical option where no infected bone has been... Continue Reading →

Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity Ulcers @ALPSLimb #ActAgainstAmputation

Important work from our Danish and Aussie colleagues Abstract Background and purpose: Clinicians and researchers utilize subjective, clinical classification systems to stratify lower extremity ulcer infections for treatment and research. The purpose of this study was to examine whether these clinical classifications are reflected in the ulcer's transcriptome. Methods: RNA-sequencing (RNA-seq) was performed on biopsies from clinically... Continue Reading →

Efficacy of topical vancomycin and gentamicin loaded calcium sulfate beads or systemic antibiotics in eradicating polymicrobial biofilms isolated from diabetic foot infections

Crowther and coworkers publish this work in Antimicrobial Agents and Chemotherapy lending further strength to the goal of maximizing antimicrobial therapy at the site of infection. Diabetic foot ulcers are notoriously difficult to heal, with ulcers often becoming chronic, in many cases leading to amputation despite weeks or months of antibiotic therapy in addition to... Continue Reading →

Up ↑

%d bloggers like this: