On diabetic foot, wound healing, amputation prevention, and the merger of consumer tech with medical devices
A pilot study published in Diabetes Care on November 30, 2023, by Johan Schoug and colleagues, presents compelling evidence on the benefits of early offloading in Charcot foot (CF), a serious complication of diabetes. The study's objective was to determine if offloading in the earliest phase of active CF, known as stage 0, could influence... Continue Reading →
The establishment of a new neurodegenerative Charcot mouse model is a potentially significant step forward in this area which has long been neglected. This study, conducted by Zachary A. Koroneos and team, offers invaluable insights into Charcot neuropathic arthropathy, a condition often associated with diabetes and known for its severe impact on the lower limbs.... Continue Reading →
Introduction: Charcot foot (CF), a significant complication in diabetic patients with distal peripheral neuropathy, has had its incidence and prevalence widely debated. A groundbreaking Swedish study, published in Diabetes Care (December 2023), now provides a comprehensive nationwide perspective. Study Overview: Spanning from 2001 to 2016, the study utilized three key Swedish registries to identify CF... Continue Reading →
The manuscript "Charcot Neuroarthropathy in Persons with Diabetes: It's Time for a Paradigm Shift in Our Thinking" by our long-time friends and colleagues Dane Wukich, Bob Frykberg, and Venu Kavarthapu, advocates for a reimagined approach in treating Charcot Neuro-Osteoarthropathy (CNO) in diabetic patients. It emphasizes surgical intervention over traditional non-surgical methods to prevent deformity and... Continue Reading →
Preliminary evaluation of dual‐energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis Great work as usual from our Dutch compatriots Objectives The purpose of this study is to evaluate the value of dual-energy CT (DECT) with virtual non-calcium (VNCa) in quantitatively assessing the presence of bone marrow... Continue Reading →
Make the link between chronic kidney disease, pedal calcification...and even Charcot? This from our SALSAmigos at Washington University, St. Louis. Aims: Determine the prevalence and relative risk of having single and combinations of biomarkers of chronic kidney disease-mineral bone disorder (CKD-MBD) syndrome in the diabetic foot from an electronic medical record (EMR) review. Methods: Review of 152... Continue Reading →
An excellent contribution to the literature from Bobirca and coworkers from Bucharest. Abstract Background: Although Charcot diabetic foot (CDF) is a frequent complication of diabetic neuropathy, less is known about the possibility of its early prevention. Methods: A review of the original articles published in English, using the “biomarkers AND Charcot’s foot” criterion, resulted in 33... Continue Reading →
From Daniel Jupiter's team in Galveston, led by Korst. This study aims to examine the duration and rate of delayed diagnosis in Charcot foot. We systematically reviewed articles published in Medline, SCOPUS, and Cumulative Index of Nursing and Allied Health Literature to identify articles discussing delayed or misdiagnosis of Charcot foot. Random-effects models were generated... Continue Reading →
Important work from Jeffcoate and Game in Diabetes Care continues the slow, steady march toward measuring, managing, and understanding what I like to call an enigma wrapped in edema. The Charcot Foot Reflects a Response to Injury That Is Critically Distorted by Preexisting Nerve Damage: An Imperfect Storm William Jeffcoate and Fran Game It has... Continue Reading →
This great resource via Maria Alves Bandeira may be downloaded here.
