BEST-CLI: The results are in and they’re likely practice-altering ActAgainstAmputation @ALPSlimb @Best_CLI #AHA22

This from our colleagues Alik Farber, Matt Menard and Ken Rosenfeld. Likely to be a game-changer in how patients with CLTI are addressed. The first results from the BEST-CLI randomised controlled trial (RCT) of 1,830 patients show that surgical bypass with adequate single-segment great saphenous vein (GSV) is a more effective revascularisation strategy for patients with chronic limb-threatening ischaemia (CLTI) who are deemed to be suitable... Continue Reading →

New Initiative Aims to Advance Equitable Care and Address Hidden Threat of Amputation Related to Peripheral Artery Disease (PAD)

Through Save Legs. Change Lives.™, Janssen seeks to elevate PAD research, collaboration, education and screening for communities placed at increased risk of cardiovascular disease — Read on http://www.jnj.com/new-janssen-initiative-aims-to-advance-equitable-care-and-address-hidden-threat-of-amputation-related-to-peripheral-artery-disease-pad Through Save Legs. Change Lives.™, Janssen seeks to elevate PAD research, collaboration, education and screening for communities placed at increased risk of cardiovascular disease TITUSVILLE, N.J., March... Continue Reading →

Two-Stage Gene Therapy (VEGF, HGF and ANG1 Plasmids) as Adjunctive Therapy in the Treatment of Critical Lower Limb Ischemia in Diabetic Foot Syndrome #ActAgainstAmputation #DiabeticFoot @ALPSlimb

It's superb work from our Polish colleagues. One of the most serious problems in people with diabetes is diabetic foot syndrome. Due to the peripheral location of atherosclerotic lesions in the arterial system of the lower extremities, endovascular treatment plays a dominant role. However, carrying out these procedures is not always possible and does not... Continue Reading →

Evolution of WIfI: Expansion of WIfI Notation After Intervention #ActAgainstAmputation @alpslimb @vascularsvs @USC_vascular @UCSFVascular @jmills1955 @VirginiePhD_POD @rowe_vincent @MME_Fernando

This from our team led by Virginie Blanchette. A proposed method of re-assessment and notation of re-assessment for patients with active disease and in remission. Nearly a decade ago, the Society for Vascular Surgery (SVS)'s wound, ischemia, and foot Infection (WIfI) classification was first developed to help assess overall limb threat. However, managing conditions such... Continue Reading →

Current Management of Peripheral Artery Disease: Focus on Pharmacotherapy @ALPSlimb @USC_Vascular @JCU @ResearchatUSC #ActAgainstAmputation

This from our combined USC and James Cook University team. Bottom line: There are lots of opportunities to make an impact to optimize best medical therapy. Jonathan Golledge, Malindu E. Fernando & David G. Armstrong Peripheral artery disease (PAD) is the occlusion or narrowing of the arteries supplying the lower extremities. Peripheral artery disease has been estimated to... Continue Reading →

Below-the-ankle arterial disease: a new marker of coronary artery disease in patients with diabetes and foot ulcers

Important work from our long-time friends Luigi Uccioli and coworkers. Some, including our friend Elissa Altin of Yale, have suggested that this might lead to us getting radiographs to identify arterial calcification that could help identify PAD, CLTI and even CAD. What do you think? Aim: The aim of the current study is to evaluate the... Continue Reading →

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