When Science Becomes Family: A Conversation on DFU, CLTI, and Recurrence Risk

Itโ€™s not every day that the professional and the personal intersect in such a deeply life-affirming way. Our latest publication in theย International Wound Journal, โ€œThree-Year Recurrence in People With Diabetic Foot Ulcers and Chronic Limb Threatening Ischemia Is Comparable to Cancer,โ€ brought together an extraordinary team of colleagues from UCSF, Baylor College of Medicine, USC,... Continue Reading →

New Nationwide Study Finds Recurrence of Diabetic Foot Ulcers and Severe Peripheral Arterial disease Comparable to Cancer

FOR IMMEDIATE RELEASE Los Angeles, CA, July 23, 2025 โ€” A new study published in the International Wound Journal highlights a striking parallel: the three-year recurrence rates for diabetic foot ulcers (DFU) and reintervention for chronic limb-threatening ischemia (CLTI) are comparable toโ€”or exceedโ€”those of advanced-stage cancers, including colorectal, breast, prostate, and even lung cancer. Led... Continue Reading →

A Call to Action โ€” By Congressional District: From the Amputation Heat Map @American_Heart #Diabetes @ALPSlimb #CLTI #ActAgainstAmputation

Making limb preservation a national priority- one congressional district at a time Does your congressman or congresswoman know where you are on the amputation heat map? Thatโ€™s not just a rhetorical question. Itโ€™s a matter of life and limb. The American Heart Associationโ€™s PAD Collaborative has unveiled a powerful tool: an interactive map showing non-traumatic lower extremity amputation... Continue Reading →

Further Exploring Tibial Periosteal Distraction as a Adjunct to Healing Diabetic Foot Ulcers

Diabetic foot ulcers (DFUs) represent one of the most significant challenges in managing diabetes-related complications. Affecting millions worldwide, DFUs lead to substantial morbidity, healthcare costs, and a heightened risk of amputation. While traditional therapies like debridement, offloading, and vascular interventions have their place, innovative solutions are crucial to improve outcomes. A recent study by Yuan... Continue Reading →

Exploring the Prognostic Role of Toe Pressures in Diabetic Foot Ulcers with Medial Arterial Calcification #PAD #CLTI #Diagnostics #DiabeticFoot #ActAgainstAmputation

In the landscape of diabetic foot care, the presence of medial arterial calcification (MAC) adds a significant layer of complexity to the management of diabetic foot ulcers (DFUs). A recent study published in the Annals of Vascular Surgery sheds light on the prognostic value of toe pressure (TP) measurements in predicting outcomes for this challenging patient population.... Continue Reading →

Exploring the Risks of SGLT2i vs. DPP-4i as Add-On Therapies in Diabetes Care #Amputation #PAD #CLTI #Stent #DiabetesCare

A new study published in Diabetes Care sheds light on the comparative risks of peripheral artery disease (PAD)-related surgical eventsโ€”such as amputations, stent placements, or vascular surgeriesโ€”between two classes of diabetes medications: sodium-glucose cotransporter 2 inhibitors (SGLT2i) and dipeptidyl peptidase 4 inhibitors (DPP-4i). Conducted among U.S. veterans, this retrospective cohort study analyzed over 150,000 episodes of medication... Continue Reading →

The Impact of Angiographic Pedal Circulation Status on Wound Healing in Chronic Limb-Threatening Ischemia After Bypass Surgery #ActAgainstAmputation #WoundHealing #WIFI

Miyake K, Kikuchi S, Uchida D, Doita T, Miyagawa S, Azuma N Understanding Pedal Circulationโ€™s Role in CLTI Wound Healing In chronic limb-threatening ischemia (CLTI), achieving complete wound healing is critical for reducing morbidity and improving patient outcomes. Although the Global Limb Anatomic Staging System (GLASS) provides a robust framework for assessing CLTI severity, its... Continue Reading →

Evaluating the Reliability of Portable Toe Pressure PPG Measurement Devices: Insights from Helsinki

The ability to accurately assess lower limb arterial circulation is critical in vascular medicine. A new study by Laamanen et al., from Maarit Venermo's unit published online inย Vascular, evaluates the reliability of a portable toe pressure (TP) photoplethysmography (PPG) device compared to a stationary laser Doppler flowmeter (LD). This investigation sheds light on whether an... Continue Reading →

Exploring Innovative Limb Salvage Techniques for CLTI – Tibial Cortex Transverse Transport (TTT) and Endovascular intervention

Introduction Chronic limb-threatening ischemia (CLTI) is a severe condition with high risks of amputation and mortality. A groundbreaking study by Ding et al. (2024) has revealed the potential of combining Tibial Cortex Transverse Transport (TTT) with Endovascular Therapy (EVT) to enhance outcomes for patients suffering from CLTI. Key Findings โ€ข At 6 months, 85.5% of... Continue Reading →

Unveiling the Future of Diabetic Foot Care: The Promise of Wearable Laser Doppler Flowmetry #ActAgainstAmputation #Wearables #DiabeticFoot

Screenshot As the prevalence of Type 2 diabetes mellitus (T2DM) continues to rise globally, the need for innovative solutions to manage its complications becomes increasingly urgent. Diabetic foot (DF) is one of the most severe complications, often leading to ulcers, infections, and even amputations. Traditional methods for assessing foot microcirculation in diabetic patients are limited... Continue Reading →

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