Tag: DFU

Scottish Nationwide Diabetic Foot Data: 5% Diabetes Prevalence, 1.1% DFU Incidence per year, Dramatically lower amputation-free Survival

Important work from our long-time SALSAmigos Graeme Leese and coworkers (Chamberlain et al) report five year data from a national Scottish database in the journal Diabetes Care. Abstract Objective: To describe incidence of foot ulceration and amputation-free survival associated with foot ulceration status in a national population-based cohort study of people with diabetes. Research design and... Continue Reading →

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First-ever “episode of care” data shows the true toll of Diabetic Foot Ulcers: Study @USC @KeckMedUSC

This from our collective team at USC / University of Michigan / University of Arizona and Podimetrics We validated a model to identify diabetic foot ulcer episodes in Medicare data.With this model, we compared morbidity and mortality rates during and after episodes.All-cause mortality was 1.5 times more likely during diabetic foot ulcer episodes.All-cause hospitalization was... Continue Reading →

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Skin autofluorescence for non-enzymatic glycation end products in Diabetic Foot Ulcers (DFUs)- A meta analysis

Continued efforts to create companion diagnostics and theragnostics to help us measure what we manage and predict DFU risk. Imagine diagnosing "friable" tissue and then doing something about it?! Objective: Skin autofluorescence (SAF) has been suggested as a novel and noninvasive technique for assessing tissue accumulation of advanced glycation end products in diabetes and related complications.... Continue Reading →

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A Meta-Analysis of the Outcomes of Resection Arthroplasty for Resistant Hallucal Diabetic Ulcers – PubMed

Great work from Yammine and Assi summarizing the state of play for this useful and still likely underutilized procedure for hallux ulcers. The standard medical care (SC) of non-infected diabetic foot ulcers (DFUs) has been reported to yield varying rates of wound healing with high recurrence rate in non-infected wounds. Conservative surgery has been advanced... Continue Reading →

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Pharmacotherapy for Diabetic Foot Ulcers- Topical and Systemic

A superb technical review from our SALSAmigos Dixon and Edmonds from King's. Historically, there has been a scarcity of evidence-based topical therapy to hasten the healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged from multicentre, randomised, controlled trials. This article highlights those trials, and describes the current pharmacological management of the... Continue Reading →

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Time’s up for diabetes-related complications. We can stop this, together.

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Study: People with Diabetic Foot Ulcers Don’t Vasodilate after Pressure Challenge. A New Marker for Risk (and Treatment Target)?

Important new work from our Lyonnaise and German colleagues published in the journal Diabetes. Neurovascular response to pressure in patients with diabetic foot ulcer Julien Vouillarmet MD1, Audrey Josset-Lamaugarny2,3, Paul Michon MD1, Jean Louis Saumet MD, PhD2,3, Audrey Koitka-Weber PhD4,5, Samir Henni MD4, Berengere Fromy PhD2,3, Dominique Sigaudo-Roussel PhD2,3 Diabetic foot ulcer (DFU) is a... Continue Reading →

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High-Resolution Spectral Analysis Accurately Identifies the Bacterial Signature in Infected Chronic Foot Ulcers in People With Diabetes

Will we soon see more visual diagnostics for wounds? Congratulations to our colleagues in Melbourne for these intriguing data. Diabetic foot infections are a major cause of hospitalization, and delayed treatment can lead to numerous complications. The aim of this research was to investigate high-resolution spectroscopy of the wound center and periwound area for real-time... Continue Reading →

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