Our colleagues Larry Lavery and Andrew Crisologo, alongside lead author Orhan รz, have published a significant prospective study in Diabetologia. Their work tackles one of the most difficult challenges in limb preservation: accurately diagnosing diabetic foot osteomyelitis (DFO) and, crucially, knowing when the infection is actually gone. The Challenge of the "Gold Standard" While bone... Continue Reading →
A 3D Panoramic View Into the Body: Introducing RUS-PAT Imaging #ActAgainstAmputation @Caltech @USC_Vascular @NeurosurgeryUSC @KeckSchool_USC @USC @NatBME
Our colleagues at Caltech and USC Vascular Surgery and Neurosurgery, including Lihong Wang, Charles Liu, Tze Woei Tan, and Jonathan Russin, have unveiled a major leap in medical imaging. Published in Nature Biomedical Engineering, the team introduces Hybrid Rotational Ultrasound and Photoacoustic Tomography (RUS-PAT). Think of it as a high-speed, 3D panoramic camera for our... Continue Reading →
Predicting Success in Spinal Cord Stimulation for the Diabetic Foot: The Role of Infrared Thermography
Spinal cord stimulation (SCS) has been an emerging therapy for patients with intractable ischemic pain and non-healing diabetic foot complications. While traditionally used for pain relief, evidence is building that SCS may also enhance blood flow, support ulcer healing, and even prolong limb salvage. But the critical question remains: who benefits most from this expensive... Continue Reading →
Inflammation, Lipids, and Limb Risk: New Clues from Two Cohorts #ActAgainstAmputation #PAD #VascularDisease #CLTI
Peripheral artery disease (PAD) is one of the most devastating complications of diabetesโcontributing to ischemic pain, functional decline, and, in severe cases, amputation. Despite its prevalence, early detection remains elusive, and clinicians continue to search for simple, reliable markers of risk. A new multicohort study led by Wang and colleagues now shines a spotlight on... Continue Reading →
Bone Biopsy or Deep Tissue Culture? The Battle for Diagnosing Diabetic Foot Osteomyelitis #ActAgainstAmputation
Screenshot Bone Biopsy vs. Deep Tissue Culture: The Smackdown for Diagnosing Diabetic Foot Osteomyelitis When it comes to diabetic foot osteomyelitis (DFO), thereโs one big question: How do we diagnose it accurately? For years, bone biopsy has been considered the heavyweight champion of diagnosisโbut itโs invasive, requires surgical skill, and isnโt always feasible. Meanwhile, deep tissue cultures offer a quicker, less... Continue Reading →
New Study Highlights Prevalence and Treatment Challenges of Diabetic Sausage Toe #ActAgainstAmputation #Osteomyelitis #DiabeticFoot
New Study Highlights Prevalence and Treatment Challenges of Diabetic Sausage Toe A recent study led by Yammine et al. (2024) sheds light on the underrecognized condition known as the "diabetic sausage toe," a presentation of osteomyelitis (OM) in diabetic patients. This study, published in the International Wound Journal, emphasizes the prevalence, clinical characteristics, and treatment... Continue Reading →
Thermography Research in Diabetic Foot: A Bibliometric Analysis @ResearchAtUSC #ActAgainstAmputation @USC_Vascular @ALPSlimb
Diabetic foot complications are among the most severe and costly consequences of diabetes mellitus, significantly impacting patients' quality of life. Recent advancements in thermography technology have demonstrated promising results in the early detection and management of diabetic foot problems. By identifying temperature variations, thermography can detect early signs of infection, thus aiding in timely intervention... Continue Reading →
Unveiling the Future of Diabetic Foot Care: The Promise of Wearable Laser Doppler Flowmetry #ActAgainstAmputation #Wearables #DiabeticFoot
Screenshot As the prevalence of Type 2 diabetes mellitus (T2DM) continues to rise globally, the need for innovative solutions to manage its complications becomes increasingly urgent. Diabetic foot (DF) is one of the most severe complications, often leading to ulcers, infections, and even amputations. Traditional methods for assessing foot microcirculation in diabetic patients are limited... Continue Reading →
Location, Location, Location: Where You Take Your Wound Biopsy Matters- Study #ActAgainstAmputation #WoundHealing
Understanding the Molecular Landscape of Chronic Cutaneous Wounds Chronic cutaneous wounds are a significant burden on healthcare systems worldwide, affecting millions of individuals and posing a challenge for medical research and patient care. A recent study by Richards et al. (2024) has provided additional insights into the molecular mechanisms underlying various common chronic ulcer types... Continue Reading →
Thermometry in the Diabetic Foot: See The Results of A Bibliographic Analysis
A recent bibliographic review by Marina Faus Camarena and colleagues, published in the journal Sensors, provides an update on the use of infrared thermography for the early detection of diabetic foot complications[1]. This non-invasive diagnostic tool could revolutionize the way we approach diabetic foot care, offering a means to detect early-stage ulcers and potentially prevent... Continue Reading →