Tag: exfix

Exploring Innovative Limb Salvage Techniques for CLTI – Tibial Cortex Transverse Transport (TTT) and Endovascular intervention

Introduction Chronic limb-threatening ischemia (CLTI) is a severe condition with high risks of amputation and mortality. A groundbreaking study by Ding et al. (2024) has revealed the potential of combining Tibial Cortex Transverse Transport (TTT) with Endovascular Therapy (EVT) to enhance outcomes for patients suffering from CLTI. Key Findings • At 6 months, 85.5% of... Continue Reading →

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Amputation versus circular external fixation in the treatment of diabetic foot with osteomyelitis: a cost and quality-of-life analysis #ActAgainstAmputation

A recent study published in Therapeutic Advances in Endocrinology and Metabolism compares two approaches for managing diabetic foot with osteomyelitis: amputation versus circular external fixation (CEF). The research highlights a pressing issue in diabetes care, as Charcot foot—a severe complication involving infected ulcers—often leads to amputation, with five-year mortality rates reaching as high as 70%.... Continue Reading →

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Exploring Tibial Cortex Transverse Transport (TTT) for Limb Preservation #ActAgainstAmputation

We are pleased to highlight more initial data with Tibial Cortex Transverse Transport (TTT). This novel approach offers a potential additional intervention for patients with chronic limb-threatening ischemia (CLTI) and severe diabetic foot ulcers (DFUs). The TTT technique, as detailed in a recent case series from our colleagues in Boston, demonstrates the potential for improved... Continue Reading →

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Potential Advance in Diabetic Wound Healing? Bone Transport and the Role of Small Extracellular Vesicles #TTT #TibialTransport #ActAgainstAmputation #Mechanism #WoundHealing #DiabeticFoot

More on what I'd like to call "therapeutic distress signals". Like NPWT, which works on skin matrices, could Ilizarov, properly used, stimulate angiogenesis at a distance? Screenshot Screenshot Even more data supporting a potential advance in diabetic wound healing, researchers have uncovered the mechanisms behind bone transport's (BT) effectiveness in treating severe diabetic foot ulcers... Continue Reading →

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Early Hemodynamic Improvement after Tibial Transport in the Diabetic Foot

The study by Liao et al. (2023) suggests significant differences in early hemodynamics after tibial transverse transport in patients with diabetic foot, focusing on those with nonarterial stenosis versus arterial stenosis. High-frequency color Doppler ultrasonography and laser Doppler flowmetry were used to assess changes. The study contributes to our understanding of diabetic foot treatment by... Continue Reading →

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Outcomes of integrated surgical wound treatment mode based on tibial transverse transport for diabetic foot wound #ActAgainstAmputation @ALPSLimb #DiabeticFoot

Congratulations to Chang and coworkers on this effort. This makes us want to reach back to work from our team a dozen or so years ago, where we failed to really explore this fascinating area of creating, in essence, a distress signal in the bone leading to upregulation of factors that can potentially help toward... Continue Reading →

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