For years, weโve operated under a simple clinical assumption: if a diabetic foot ulcer (DFU) is infected, we reach for the antibioticsโoften broad-spectrum heavy hitters like levofloxacin. But new molecular evidence suggests that while we are busy fighting bacteria, we may be unintentionally collateral-damaging the woundโs own healing machinery. A recent study published in Scientific... Continue Reading →
Mechanisms of diabetic foot ulceration
Mechanisms of diabetic foot ulceration: A review Here's the summary of this manuscript by Deng and coworkers: โข Diabetic foot ulcers (DFUs) are a serious complication of diabetes, with complex pathogenic factors. โข Previous studies focused on diabetic peripheral vascular disease, neuropathy, and wound infections. โข Researchers are now studying immune cells, endothelial cells, keratinocytes,... Continue Reading →
Bioinformatic Analysis Reveals Hub Immune-Related Genes of Diabetic Foot Ulcers #ActAgainstAmputation
This from Rong and coworkers Summary Points: Diabetic foot ulcer (DFU) is a complex and devastating complication of diabetes mellitus that are usually stagnant in the inflammatory phase.However, oral wound healing, which is characterized by a rapid and scarless healing process, is regarded an ideal model of wound healing.Thus, we performed a comprehensive bioinformatics analysis... Continue Reading →