A cost-effectiveness analysis of the DIAFOS trial shows that in-shoe plantar pressure-guided custom footwear saves over โฌ8,000 per ulcer prevented โ and adherent patients push the probability of cost-effectiveness to 94%. The economic case for prevention just got stronger.
Control-Alt-Delete: Rebooting the Chronic Wound #ActAgainstAmputation #DFU #WoundHealing @ALPSLimb @KeckSchool_USC @USC_Vascular
Chronic wounds are biological computers stuck in a boot loop. Sharp debridement is Control-Alt-Delete โ the histological reboot that converts a chronic wound back into an acute one. Only then can you run the apps.
One in Three: What the First Year of DFU Remission Really Looks Like #ActAgainstAmputation @DiabetologyMdpi @ALPSLimb @KeckSchool_USC #DFU #Remission #Survivorship
A new systematic review finds that roughly one in three adults in remission after a healed diabetic foot ulcer develop a recurrent ulcer within 12 months โ a risk comparable to several common cancers. Healing is the beginning of the next chapter, not the end of the story.
Compromised Skin Barrier at Wound Closure Predicts Recurrence of Diabetic Foot Ulcers: A New TEWL? #ActAgainstAmputation @NIDDKGov #DFC @DiabetesCareADA @ALPSLimb
I An important multicenter study from our colleagues Sen and coworkers and the NIHโs Diabetic Foot Consortium, conducted through the NIDDK Diabetic Foot Consortium, has provided strong evidence that functional closureโnot just structural closureโmatters when it comes to diabetic foot ulcers (DFUs). Published in Diabetes Care, this prospective noninterventional study followed 418 patients with recently... Continue Reading →
New Nationwide Study Finds Recurrence of Diabetic Foot Ulcers and Severe Peripheral Arterial disease Comparable to Cancer
FOR IMMEDIATE RELEASE Los Angeles, CA, July 23, 2025 โ A new study published in the International Wound Journal highlights a striking parallel: the three-year recurrence rates for diabetic foot ulcers (DFU) and reintervention for chronic limb-threatening ischemia (CLTI) are comparable toโor exceedโthose of advanced-stage cancers, including colorectal, breast, prostate, and even lung cancer. Led... Continue Reading →
Quantifying and Communicating the Severe Outcomes of Diabetic Foot Disease in Type 2 Diabetes including Amputation, Cardiovascular Events, and Death #ActAgainstAmputation @ALPSlimb
Diabetic Foot Disease (DFD) is a significant complication of Type 2 Diabetes Mellitus (T2DM), often leading to severe outcomes, including increased mortality. A recent study published in Cardiovascular Diabetology provides crucial insights into the risks associated with DFD, emphasizing the need for early intervention and improved management strategies for individuals with T2DM. Study Overview The... Continue Reading →
Evolution of WIfI: Expansion of WIfI Notation After Intervention #ActAgainstAmputation @alpslimb @vascularsvs @USC_vascular @UCSFVascular @jmills1955 @VirginiePhD_POD @rowe_vincent @MME_Fernando๏ฟผ๏ฟผ๏ฟผ
This from our team led by Virginie Blanchette. A proposed method of re-assessment and notation of re-assessment for patients with active disease and in remission. Nearly a decade ago, the Society for Vascular Surgery (SVS)'s wound, ischemia, and foot Infection (WIfI) classification was first developed to help assess overall limb threat. However, managing conditions such... Continue Reading →
Effects of wear and tear of therapeutic footwear in patients remission. A 5-year follow-up study #ActAgainstAmputation
More wonderful work from our long-time SALSAmigos from the Complutense in Madrid. Aims to assesses the relationship between the wear and tear of therapeutic footwear (TF) and the risk of recurrence in diabetes remission patients. Methods Remission patients (N=115) participated in this 5-year prospective study in a specialized Diabetic Foot Unit between October 2016 and... Continue Reading →
Poor sleep and hypoxemia may be associated with longer wound healing and more frequent ulcer recurrence in remission
Fascinating work from Chen and coworkers. Perhaps something else we need to focus on that we often acknowledge but frequently neglect! STUDY OBJECTIVES: Sleep-disordered breathing (SDB) is prevalent and associated with increased risk of morbidity and mortality. However, whether SDB has an adverse impact on wound healing in patients with diabetic foot ulcers (DFUs) is... Continue Reading →
Patients in diabetic foot remission are at highest risk for future events #ActAgainstAmputation #Remission
Mader and coworkers present data that further highlight the importance of focusing on the patient in diabetic foot remission. Patients with previous diabetic foot ulcer are prone to re-ulceration and (re)amputation, to various comorbidities, have significantly impaired quality of life and increased mortality. We aimed to evaluate the risk of foot related complications and mortality... Continue Reading →